Hearing Loss, Sensorineural ; diagnosis ; prevention & control ; Humans

Hearing Loss, Sensorineural ; diagnosis ; therapy ; Humans

Humans ; Hearing Loss, Sensorineural/diagnosis* ; Deafness ; Mutation

OBJECTIVE: To investigate the current situation of early diagnosis and intervention in 0-9 months old infants with hearing loss and analysis factors that will affect early diagnosis and intervention. METHOD: One hundred and eighty-six infants referred to the West China hospital from February 2014 to September 2014 were included. All 186 children were referred due to the fact that either they failed infant hearing screening or outer ear malformation. Early diagnosis and/or intervention were performed on those 186 children and their records of early diagnosis and intervention were analyzed. RESULT: Among the 186 infants, 167 (89.8%) were diagnosed with an average age at (4.0 ± 1.4) months. Among the 167 infants with final diagnosis, there were 31 (18.6%) infants diagnosed as conductive hearing loss (CHL), and 99 cases (59.3%) diagnosed as sensorineural hearing loss (SNHL), among whom, there were 75 (44.9%) bilateral SNHL and 24 (14.4%) unilateral SNHL. There were 2 cases (1.20%) with SNHL on one side and atresia on the other side. 5 (2.99%) of all conductive hearing loss cases with unilateral atresia and 2 cases with auditory neuropathy (AN) were found. 33 infants (19.8%) were found to have normal hearing. 30.7% (23/75) infants diagnosed as bilateral SNHL and 8.3% (2/24) infants diagnosed as unilateral SNHL were fitted with hearing aids. The fitting rate in infants with bilateral SNHL with mild, moderate, severe to profound degrees were 0 (0/23), 24.0% (6/25), 66.7% (6/9), 61.1% (11/18) respectively. The average intervention age was (5.0 ± 2.1) months. CONCLUSION Although the early diagnosis and intervention situation in this study are very close to international standard, there are still infants without final diagnosis and infants with hearing loss without hearing aid fitting. Further studies and efforts to promote early diagnosis and intervention in infants with hearing loss are needed.
China ; Deafness ; Early Diagnosis ; Hearing Aids ; Hearing Loss, Bilateral ; Hearing Loss, Central ; Hearing Loss, Conductive ; diagnosis ; Hearing Loss, Sensorineural ; diagnosis ; Hearing Tests ; Humans ; Infant ; Infant, Newborn

BACKGROUND AND OBJECTIVES: Sudden deafness in children is rare and comprises less than 10% of all sudden deafness. Viral infection is more common and early treatment is less common in children than in adults. Prognosis of sudden deafness is poorer in children than in adults. This study was attempted to evaluate clinical characteristics and prognosis of sudden deafness in children and to compare with sudden deafness in adults. Materials and Methods: We reviewed the records of 40 patients (41 ears) who had been admitted to the department of otolaryngology, Pusan National University Hospital from January 1990 to December 2000. RESULTS: 1) Hearing recovery was significantly worse in the age group below 10 than in that over 10 (p<0.05). 2) Hearing recovery was less favorable in patients with profound degree of hearing loss than in those with the other degrees of hearing loss (p<0.05). 3) The patients who had been treated within 7 days after the on-set of symptoms were smaller in children than in adults (p<0.05). 4) Mumps was more common in childhood, the hearing recovery was significantly worse in cases with mumps than those without mumps (p<0.05). 5) Of the 41 ears, 8 ears (19.5%) had complete recovery, 5 ears (12.2%) had partial recovery, 9 ears (22.0%) had slight improvement, 19 ears (46.3%) had no improvement. CONCLUSION: Congenital hereditary deafness and viral infections are more common in children. Thus the cause of sudden sensorineural hearing loss can be identified more frequently in children than in adults. Poor hearing recovery in children are considered to be associated with late time of initial treatment and asymptomatic mumps. Early diagnosis and early treatment are more important in children.
Adult ; Busan ; Child* ; Deafness ; Ear ; Early Diagnosis ; Hearing ; Hearing Loss ; Hearing Loss, Sensorineural ; Hearing Loss, Sudden* ; Humans ; Mumps ; Otolaryngology ; Prognosis

Bilateral sensorineural hearing loss (SNHL) is a relatively well-recognized complication of bacterial meningitis, but is a rare initial manifestation in acute cryptococcal meningitis. We report a case of cryptococcal meningitis initially presenting with bilateral SNHL. Cryptococcal meningitis should be included in the differential diagnosis of abrupt-onset bilateral SNHL.
Diagnosis, Differential ; Hearing Loss, Sensorineural* ; Meningitis, Bacterial ; Meningitis, Cryptococcal*

The cochlear dead regions are common exist in the case of moderate to profound sensorineural hearing loss. Patients with dead regions have demonstrated poor understanding of speech in noise and report less satisfaction with hearing aids than patients with no dead regions. Dead regions are assumed to occur if a hearing-impaired listener can be shown to be using off-place listening. A correctly diagnosed dead regions facilitates accurate and informed aural rehabilitation.
Cochlea ; physiopathology ; Hearing Loss, Sensorineural ; diagnosis ; rehabilitation ; Humans

Next-generation sequencing (NGS) technologies have improved as well as the costs have gradually decreased in the detections of genetic diseases. This article describes the principle, platform, and data analysis of NGS and the application of NGS technologies to the molecular diagnosis of hereditary hearing loss (HL). The use of NGS technologies makes the discovery of HL genes more feasible than ever. And the data obtained by NGS used in genetic counseling for clinical practice may assist in defining genetic profiles of HL individuals and expedite the pace of personalized medical care.
Hearing Loss, Sensorineural ; diagnosis ; genetics ; High-Throughput Nucleotide Sequencing ; Humans

Deafness ; Hearing Loss/etiology* ; Hearing Loss, Sensorineural ; Humans ; Meningitis, Cryptococcal/diagnosis*

Low frequency sensorineural deafness is a common subtype of idiopathic sudden deafness. Certain patients suffered recurrent attacks without vertigo, much alike Meniere's disease. Few of them developed into definite Meniere's disease during long-term follow-up in many clinical studies. Although the pathophysiology of recurrent low frequency deafness is yet unknown, the desease is considered associated with early state of endolymphatic hydrops or migraine. Otologists shall be aware of its clinical course and careful explanation is necessary at time of initial informed consent.
Endolymphatic Hydrops ; complications ; Hearing Loss, Sensorineural ; complications ; diagnosis ; Hearing Loss, Sudden ; Humans ; Meniere Disease ; complications ; Vertigo