2.Multimorbidity patterns and associated hospitalization costs among different age groups of patients in a single medical center.
Tao LI ; Xiaolin XU ; Yangyang CHENG ; Kai LIN
Journal of Zhejiang University. Medical sciences 2025;54(4):423-433
OBJECTIVES:
To analyze the multimorbidity patterns and core diseases among hospitalized patients in different age groups and to explore the impacts of multimorbidity patterns on hospitalization costs.
METHODS:
Electronic medical records of adult inpatients (aged ≥18 years) from Ningbo Medical Center Lihuili Hospital between January 1, 2018, and June 30, 2023 were collected. The multimorbidity status involving 53 specific diseases was analyzed across different age groups. Association rule mining was used to identify common multimorbidity patterns. Complex network analysis was used to identify core diseases within the multimorbidity networks. Generalized estimating equations (GEE) were used to analyze the impact of different multimorbidity patterns on hospitalization costs.
RESULTS:
The prevalence of multimorbidity among the 359 402 adult inpatients was 38.51%, with higher rates observed in males (43.60%) and elderly patients (58.29%). Association rule mining identified 15 common multimorbidity patterns, which exhibited differences across age groups. The most prevalent multimorbidity pattern overall was "diabetes→hypertension" (support=7.04%, confidence=62.17%, lift=2.17). In the young adult group, the most prevalent pattern was "dyslipidemia→chronic liver disease" (support=1.19%, confidence=53.17%, lift=6.04). In the middle-aged group, it was "diabetes→hypertension" (support=4.84%, confidence=50.28%, lift=2.15). In the elderly group, it was "coronary heart disease, diabetes→hypertension" (support=2.38%, confidence=77.43%, lift=1.63). Complex network analysis revealed that the core diseases within multimorbidity networks differed across age groups. The core disease identified in the young adult group was chronic liver disease (degree centrality=50, betweenness centrality=0.055, closeness centrality=0.963). Core diseases in the middle-aged group included hypertension, chronic liver disease, and diabetes (all with degree centrality=52, betweenness centrality=0.022, closeness centrality=1.000). Core diseases in the elderly group comprised hypertension, diabetes, malignant tumors, chronic liver disease, thyroid disease, anemia, and arrhythmia (all with degree centrality=52, betweenness centrality=0.009, closeness centrality=1.000). Generalized estimating equations analysis indicated that, most multimorbidity patterns were significantly associated with increased hospitalization costs. However, the magnitude of cost increase varied across different multimorbidity patterns. Specifically, hospitalization costs for patients with patterns such as "heart failure→hypertension", "stroke→hypertension", "malignant tumor, diabetes→hypertension", "stroke, diabetes→hypertension", and "diabetes, heart failure→hypertension" were more than double those of patients without any target diseases.
CONCLUSIONS
Multimorbidity patterns and core diseases among hospitalized patients differ significantly across age groups, and different patterns exert varying impacts on hospitalization costs. These findings underscore the necessity for age-stratified and multimorbidity pattern specific management strategies.
Humans
;
Multimorbidity
;
Male
;
Hospitalization/economics*
;
Female
;
Aged
;
Middle Aged
;
Adult
;
Age Factors
;
Young Adult
;
Adolescent
;
Diabetes Mellitus/epidemiology*
;
Electronic Health Records
;
Aged, 80 and over
;
Hospital Costs
;
China/epidemiology*
;
Hypertension/economics*
;
Liver Diseases/epidemiology*
3.The cost of primary care: An experience analysis in an urban setting
Mia P. Rey ; Regine Ynez H. De Mesa ; Jose Rafael A. Marfori ; Noleen Marie C. Fabian ; Romelei Camiling-Alfonso ; Ramon Pedro P. Paterno ; Nannette B. Sundiang ; AB Yusoph ; Leonila F. Dans ; Cara Lois T. Galingana ; Ma. Rhodora N. Aquino ; Josephine T. Sanchez ; Jesusa T. Catabui ; Antonio Miguel L. Dans
Acta Medica Philippina 2024;58(Early Access 2024):1-12
Objectives:
PhilHealth’s present health benefit scheme is largely centered on in-patient services. This inadvertently incentivizes hospital admissions for increased access to benefit coverage. To address this problem, this study proposes a costing method to comprehensively finance outpatient care. The objective of this paper is to estimate an annual primary care benefit package (PCBP) cost based on experience analysis (actual benefit usage) on the first year of implementation at an urban pilot site.
Methods:
A cost analysis was conducted to assess a disease-agnostic primary care benefit package for an urban
outpatient government facility over the first year of implementation. Costing information was gathered through staff interviews, accounting documents, and usage data from the electronic health records system available on-site.
Results:
The annual primary care cost was defined as the estimated financial coverage for eligible employees and their eligible dependents (n=15,051). The annual utilization rate for consultations was reported at 51%. Of patients who consulted, approximately 38% accessed free available diagnostic procedures and 48% availed of free available medicines. Based on these usage rates, the annual primary care cost for the first year was computed at PhP 403.22 per capita.
Conclusion
Our study shows that on the first year of coverage in a government run urban outpatient facility, an
allocation of PhP 403.22 per capita can allow coverage for a disease-agnostic package (comprehensive); this amount excludes out-of-pocket expenses incurred by the target population of this study. This amount is feasible only when coopted with opportunistic registration, reduction of untargeted check-ups, prior contextual community engagement, and streamlining of patient-transactions through an electronic health record (EHR).
Healthcare Financing
;
Costs and Cost Analysis
;
Primary Health Care
4.The cost of primary care: An experience analysis in an urban setting
Mia P. Rey ; Regine Ynez H. De Mesa ; Jose Rafael A. Marfori ; Noleen Marie C. Fabian ; Romelei Camiling-Alfonso ; Ramon Pedro P. Paterno ; Nannette B. Sundiang ; Ab Yusoph ; Leonila F. Dans ; Cara Lois T. Galingana ; Ma. Rhodora N. Aquino ; Josephine T. Sanchez ; Jesusa T. CATABUI ; Antonio Miguel L. Dans
Acta Medica Philippina 2024;58(23):7-18
OBJECTIVES
PhilHealth’s present health benefit scheme is largely centered on in-patient services. This inadvertently incentivizes hospital admissions for increased access to benefit coverage. To address this problem, this study proposes a costing method to comprehensively finance outpatient care. The objective of this paper is to estimate an annual primary care benefit package (PCBP) cost based on experience analysis (actual benefit usage) on the first year of implementation at an urban pilot site.
METHODSA cost analysis was conducted to assess a disease-agnostic primary care benefit package for an urban outpatient government facility over the first year of implementation. Costing information was gathered through staff interviews, accounting documents, and usage data from the electronic health records system available on-site.
RESULTSThe annual primary care cost was defined as the estimated financial coverage for eligible employees and their eligible dependents (n=15,051). The annual utilization rate for consultations was reported at 51%. Of patients who consulted, approximately 38% accessed free available diagnostic procedures and 48% availed of free available medicines. Based on these usage rates, the annual primary care cost for the first year was computed at PhP 403.22 per capita.
CONCLUSIONOur study shows that on the first year of coverage in a government run urban outpatient facility, an allocation of PhP 403.22 per capita can allow coverage for a disease-agnostic package (comprehensive); this amount excludes out-of-pocket expenses incurred by the target population of this study. This amount is feasible only when coopted with opportunistic registration, reduction of untargeted check-ups, prior contextual community engagement, and streamlining of patient-transactions through an electronic health record (EHR).
Primary Health Care ; Health Policy ; Healthcare Financing ; Costs And Cost Analysis
5.Perioperative emergency laparotomy pathway for patients undergoing emergency laparotomy: A propensity score matched study.
Joel Wen Liang LAU ; Janardhan BALIGA ; Faheem KHAN ; Ying Xin TEO ; Jonathan Ming Jie YEO ; Vincent Zhiwei YEOW ; Christine Xia WU ; Stephanie TEO ; Tracy Jia Hui GOH ; Philip IAU
Annals of the Academy of Medicine, Singapore 2024;53(12):713-723
INTRODUCTION:
Emergency laparotomy (EL) is associated with high morbidity and mortality, often exceeding 10%. This study evaluated the impact of the EMergency Laparotomy Audit (EMLA) interdisciplinary perioperative pathway on patient outcomes, hospital costs and length of stay (LOS) within a single centre.
METHOD:
A prospective cohort study was conducted from August 2020 to July 2023. The intervention team included specialist clinicians, hospital administrators and an in-hospital quality improvement team. Patients who underwent EL were divided into a pre-intervention control group (n=136) and a post-intervention group (n=293), and an 8-item bundle was implemented. Propensity scoring with a 1:1 matching method was utilised to reduce confounding and selection bias. The primary outcomes examined were LOS, hospitalis-ation costs and surgical morbidity, while secondary outcomes included 30-day mortality and adherence to the intervention protocol.
RESULTS:
The utilisation of the EMLA perioperative care bundle led to a significant reduction in surgical complications (34.8% to 20.6%, P<0.01), a decrease in LOS by 3.3 days (15.4 to 12.1 days, P=0.03) and lower hospitalisation costs (SGD 40,160 to 30,948, P=0.04). Compliance with key interventions also showed improvement. However, there was no difference in 30-day mortality.
CONCLUSION
This study offers insights on how surgical units can implement systemic perioperative changes to improve outcomes for patients undergoing emergency laparotomy.
Humans
;
Laparotomy/methods*
;
Propensity Score
;
Female
;
Male
;
Prospective Studies
;
Length of Stay/statistics & numerical data*
;
Middle Aged
;
Hospital Costs/statistics & numerical data*
;
Postoperative Complications/epidemiology*
;
Aged
;
Emergencies
;
Perioperative Care/methods*
;
Critical Pathways
;
Singapore
;
Adult
6.Analysis of the direct economic burden of measles cases and its influencing factors in Shanghai from 2017 to 2019.
Xiang GUO ; Jian Fang DUAN ; Zhi LI ; Jing QIU ; Xiao Ying MA ; Zhuo Ying HUANG ; Jia Yu HU ; Xiu Fang LIANG ; Xiao Dong SUN
Chinese Journal of Preventive Medicine 2023;57(6):857-862
Objective: To analyze the direct economic burden caused by measles cases in Shanghai from 2017 to 2019 and its influencing factors. Methods: A total of 161 laboratory-confirmed measles cases reported from January 1, 2017, to December 31, 2019, in Shanghai were included in the study through the "Measles Surveillance Information Reporting and Management System" of the "China Disease Surveillance Information Reporting and Management System". Through telephone follow-up and consulting hospital data, the basic information of population, medical treatment situation, medical treatment costs and other information were collected, and the direct economic burden of cases was calculated, including registration fees, examination fees, hospitalization fees, medical fees and other disease treatment expenses, as well as transportation and other expenses of cases. The multiple linear regression model was used to analyze the main influencing factors of the direct economic burden. Results: The age of 161 measles cases M (Q1, Q3) was 28.21 (13.33, 37.00) years. Male cases (56.52%) were more than female cases (43.48%). The largest number of cases was≥18 years old (70.81%). The total direct economic burden of 161 measles cases was 540 851.14 yuan, and the per capita direct economic burden was 3 359.32 yuan. The direct economic burden M (Q1, Q3) was 873.00 (245.01, 4 014.79) yuan per person. The results of multiple linear regression model analysis showed that compared with other and unknown occupations, central areas and non-hospitalized cases, the direct economic burden of measles cases was higher in scattered children, childcare children, students, and cadre staff in the occupational distribution, suburban areas and hospitalized, with the coefficient of β (95%CI) values of 0.388 (0.150-0.627), 0.297 (0.025-0.569), 0.327 (0.148-0.506) and 1.031 (0.853-1.209), respectively (all P values<0.05). Conclusion: The direct economic burden of some measles cases in Shanghai is relatively high. Occupation, area of residence and hospitalization are the main factors influencing the direct economic burden of measles cases.
Child
;
Humans
;
Male
;
Female
;
Adolescent
;
Financial Stress
;
Cost of Illness
;
China/epidemiology*
;
Health Care Costs
;
Measles/epidemiology*
7.Comparison of hospital delivery costs between cesarean section and natural delivery and analysis of influencing factors.
Sisi OUYANG ; Zhenzhen YAO ; Wen DAI ; Yixu LIU ; Puying LIU ; Jiayou LUO
Journal of Central South University(Medical Sciences) 2023;48(5):733-742
OBJECTIVES:
The increasing costs of hospital delivery have increased the economic burden of pregnant women, and the mode of delivery is the main factor affecting the costs of hospital delivery. This study aims to explore the difference in costs between cesarean section and natural delivery, and to provide reference for controlling the increase of hospital delivery costs.
METHODS:
The data of inpatient delivery in the Hunan Maternal and Child Health Care Hospital from January 2016 to December 2020 were selected to compare the total inpatient costs and average daily costs of cesarean section and natural delivery. The linear trend model was used to analyze the trend change of inpatient delivery costs and the generalized linear model was used to analyze the influential factors for inpatient delivery costs.
RESULTS:
The average hospitalization costs of cesarean section (10 447.25 yuan) were higher than that of natural delivery (5 567.95 yuan), and the average daily costs of cesarean section (1 902.57 yuan) were higher than those of natural delivery (1 666.40 yuan). There was no significant increase or decrease in trend for cesarean section, while the average annual growth rate of the costs of natural delivery was 11.79%. The main factors affecting the hospitalization costs of cesarean section and natural delivery included age, occupation, medical insurance, route of admission, length of stay, premature delivery and complications (all P<0.05).
CONCLUSIONS
The total hospitalization costs and average daily costs of cesarean section are higher than those of natural delivery, but the costs of natural delivery show a faster growth trend, and the hospitalization costs of cesarean section and natural delivery should be controlled by targeted measures.
Child
;
Female
;
Pregnancy
;
Humans
;
Cesarean Section
;
Hospitalization
;
Hospitals
;
Hospital Costs
;
Inpatients
;
Retrospective Studies
8.Cost analysis of a Patient-Centred Medical Home for community-dwelling older adults with complex needs in Singapore.
Grace SUM ; Mumtaz Mohamed KADIR ; Soon Hoe HO ; Joanne YOONG ; Junxing CHAY ; Chek Hooi WONG
Annals of the Academy of Medicine, Singapore 2022;51(9):553-566
INTRODUCTION:
The Patient-Centred Medical Home (PCMH) demonstration in Singapore, launched in November 2016, aimed to deliver integrated and patient-centred care for patients with biopsychosocial needs. Implementation was based on principles of comprehensiveness, coordinated care and shared decision-making.
METHOD:
We conducted a prospective single-arm pre-post study design, which aimed to perform cost analysis of PCMH from the perspectives of patients, healthcare providers and society. We assessed short-to-intermediate-term health-related costs by analysing data on resource use and unit costs of resources.
RESULTS:
We analysed 165 participants enrolled in PCMH from November 2017 to April 2020, with mean age of 77 years. Compared to the 3-month period before enrolment, mean total direct and indirect participant costs and total health system costs increased, but these were not statistically significant. There was a significant decrease in mean cost for primary care (government primary care and private general practice) in the first 3-month and second 3-month periods after enrolment, accompanied by a significant decrease in service utilisation and mean costs for PCMH services in the second 3-month period post-enrolment. This suggested a shift in resource costs from primary care to community-based care provided by PCMH, which had added benefits of both clinic-based primary care and home-based care management. Findings were consistent with a lower longer-term cost trajectory for PCMH after the initial onboarding period. Indirect caregiving costs remained stable.
CONCLUSION
The PCMH care model was associated with reduced costs to the health system and patients for usual primary care, and did not significantly change societal costs.
Aged
;
Health Care Costs
;
Humans
;
Independent Living
;
Patient-Centered Care
;
Prospective Studies
;
Singapore
9.Healthcare cost of patients with multiple chronic diseases in Singapore public primary care setting.
Shu Yun TAN ; Kaiwei Jeremy LEW ; Ying XIE ; Poay Sian Sabrina LEE ; Hui Li KOH ; Yew Yoong DING ; Eng Sing LEE
Annals of the Academy of Medicine, Singapore 2021;50(11):809-817
INTRODUCTION:
The rising prevalence of multiple chronic diseases is an important public health issue as it is associated with increased healthcare utilisation. This paper aimed to explore the annual per capita healthcare cost in primary care for patients with multiple chronic diseases (multimorbidity).
METHODS:
This was a retrospective cohort study conducted in a cluster of public primary care clinics in Singapore. De-identified data from electronic medical records were extracted from July 2015 to June 2017. Only patients with at least 1 chronic disease were included in the study. Basic demographic data and healthcare cost were extracted. A list of 20 chronic diseases was considered for multimorbidity.
RESULTS:
There were 254,377 patients in our study population, of whom 52.8% were female. The prevalence of multimorbidity was 62.4%. The median annual healthcare cost per capita for patients with multimorbidity was about twice the amount compared to those without multimorbidity (SGD683 versus SGD344). The greatest percentage increment in cost was when the number of chronic diseases increased from 2 to 3 (43.0%).
CONCLUSION
Multimorbidity is associated with higher healthcare cost in primary care. Since evidence for the optimal management of multimorbidity is still elusive, prevention or delay in the onset of multimorbidity in the general population is paramount.
Chronic Disease
;
Comorbidity
;
Cross-Sectional Studies
;
Female
;
Health Care Costs
;
Humans
;
Prevalence
;
Primary Health Care
;
Retrospective Studies
;
Singapore/epidemiology*
10.Economic burden and factors associated with Crohn's disease.
Wu Ping ZHOU ; Nan MU ; Wei Yan JIAN ; Hua Hong WANG
Journal of Peking University(Health Sciences) 2021;53(3):555-559
OBJECTIVE:
To study the economic burden of Crohn's disease and its related factors, and to provide opinions for reducing personal burden and improving reimbursement policy.
METHODS:
Using a cross-sectional method, a self-created questionnaire based on the basic principles of health services research was used to survey Crohn's disease patients served by the Shanghai volunteer service foundation platform. Information collected included basic characteristics, therapy, and medical costs related to Crohn's disease in the past 12 months. Descriptive statistics were used to analyse the composition of inpatient and outpatient costs of Crohn's disease for treatment of the disease in the past year. Further, a logarithm-linear model was constructed to analyse the factors associated with the financial burden of Crohn's disease.
RESULTS:
In the study, 820 questionnaires were distributed and 799 questionnaires were returned, of which 797 were valid. There were 528 (66.25%) males and 269 (33.75%) females. The mean age of the patients was (34.02±11.49) years, with a concentration between 18-39 years (510 cases, 63.99%) and a mean disease duration of (5.58±5.13) years. 10.7% of the patients did not receive continuous treatment, and the average annual treatment cost for the patients with continuous treatment was 54 246 Yuan, of which 30 279 Yuan (55.8%) was paid by the individuals and 23 966 Yuan (44.2%) was paid by the insurance. The personal financial burden was close to the national per capita disposable income in 2020, which was 32 189 Yuan (94.1%), exceeding the annual cost for type 2 diabetes in China in 2016, 8 245 Yuan. In terms of the distribution of outpatient and inpatient services, the average annual cost of inpatient services was 31 092 Yuan, of which 14 673 Yuan (48.5%) was paid out of pocket by the individuals and 16 418 Yuan (51.5%) was paid by the insurance; the average annual cost of outpatient services was 23 154 Yuan, of which 15 606 Yuan (65.1%) was paid out of po-cket by the individuals and 7 548 Yuan (34.9%) was paid by the insurance. The personal burden of outpatient care was higher than of inpatient care. The regression results of the logarithm-linear model showed that the total annual treatment cost was related to the duration of illness (β=0.03, P < 0.01), having complications (β=-0.68, P < 0.01), receiving surgical treatment (β=0.52, P < 0.01), using immunosuppressive drugs (β=0.51, P < 0.01), annual outpatient visits (β=0.02, P < 0.05), and number of hospitalizations per year (β=0.08, P < 0.01).
CONCLUSION
The annual financial burden for patients with Crohn's disease is heavy and rises significantly with the duration of illness, exceeding that of chronic diseases such as diabetes. The personal financial burden is close to the national per capita disposable income, and the medical security department should develop policies to reduce the financial burden. The inclusion of Crohn's disease as a special outpatient disease is a possible measure that could be considered in response to the fact that the outpatient personal financial burden is heavier than the inpatient's.
Adult
;
China/epidemiology*
;
Cost of Illness
;
Crohn Disease/therapy*
;
Cross-Sectional Studies
;
Diabetes Mellitus, Type 2
;
Female
;
Health Care Costs
;
Humans
;
Male
;
Middle Aged
;
Young Adult


Result Analysis
Print
Save
E-mail