1.Early Onset Generalized Pustular Psoriasis Accompanying IL36 Receptor Antagonist (IL36RN) Gene Mutation in a 14-year-old Korean Male Patient with No Family History.
Kyung Hea PARK ; Weon Ju LEE ; Seok Jong LEE ; Do Won KIM ; Yong Hyun JANG
Korean Journal of Dermatology 2014;52(2):151-153
No abstract available.
Adolescent*
;
Humans
;
Male*
;
Psoriasis*
2.Accompanied Histopathologic Findings and Association of Serum beta-HCG Levels with Myosalpingeal Invasion in Ectopic Tubal Pregnancy.
Hye Jin PARK ; Ho Jung KIM ; Hea Soo KOO ; Sun Hee SUNG ; Won Sup HAN
Korean Journal of Pathology 1999;33(7):497-502
Most ectopic pregnancies occur in the fallopian tubes. There have been numerous theories to explain the occurrence of ectopic pregnancy in fallopian tubes. The most commonly held view is that the passage of the fertilized ovum through the fallopian tube is delayed or hindered by chronic inflammation and its sequelae. We designed a study to evaluate the details of histopathologic changes and the location of implantation and how they relate to the clinical history. 182 fallopian tube specimens from patients who had undergone total or partial salpingectomy were examined. A high incidence of non-specific inflammation of plicae and wall of tube (31.9%) and salpingitis isthmica nodosa (12.6%) were observed. Other associated findings included acute salpingitis, complex plicae or complex hyperplasia of tubal epithelium, fibrous adhesion with ovary, endometriosis, and calcification. History of previous ectopic tubal pregnancy was found in 8 cases. The cases with serum beta-HCG value above 2,500 I.U./L (group I, n=97) were more frequently noted in those exhibiting myosalpingeal invasion of trophoblast (67 cases) than in those without invasion (30 cases). Of the 182 tubal pregnancies, 117 (64.3%) cases were found in the ampulla and 47 (25.8%) cases in isthmic location. In 117 ampullary pregnancies, the products of conception were found intraluminally in 71 cases (60.7%), and extraluminally in 34 (29.1%) cases, of which the products of conception were found entirely extraluminal. The products of conception, found both within and outside the tubal lumen, were found in 12 cases (10.2%). Of 47 tubes with isthmic pregnancies, 33 cases were intraluminal (70.2%), 12 cases were extraluminal (25.5%), and two cases were mixed (4.3%). In conclusion, significant histopathologic abnormalities accompany a majority of ectopic tubal pregnancy, and myosalpingeal invasion of trophoblast is correlated with high serum beta-HCG. Thus, it is necessary to confirm not only the ectopic placental tissue but also the accompanying details of the other histopathologic findings or the pathologic evaluation of ectopic tubal pregnancy.
Endometriosis
;
Epithelium
;
Fallopian Tubes
;
Female
;
Fertilization
;
Humans
;
Hyperplasia
;
Incidence
;
Inflammation
;
Ovary
;
Pregnancy
;
Pregnancy, Ectopic
;
Pregnancy, Tubal*
;
Salpingectomy
;
Salpingitis
;
Trophoblasts
;
Zygote
3.Dose Response of Intravenous Thiopental for Induction of General Anesthesia in Cesarean Section Patients and in Patients with End Stage Renal Disease.
Won Oak KIM ; Hea Keum KIL ; Jong Rae KIM ; Kwang Won PARK
Korean Journal of Anesthesiology 1988;21(6):942-946
The dose-response of intravenous thiopental (2.5%) for induction of general anesthesia in cesarean section (C/S) patients and in patients with end stage renal disease(ESRD) was studied at seven doses of 2.0, 3.0, 3.5, 4.0, 4.5, 5.0 and 6.0 mg/kg body weight. Thiopental was injected as an IV bolus into a preexisting IV catheter. Patients were divided into four groups(ESRD-CONTROL, C/S-CONTROL, C/S, and ESRD). Each patient was examined at 60 seconds after injection of thiopental. Presence or absence of verbal command response, lid reflex and trapexius reflex were observed. For each reflex, dose-response curves were analysed using the log probit model to determine ED 50, Ed95 and parallelism. The value of ED50 for verbal command response was lowest in the ESRD patient group (2.2mg/kg) and was similar in the remaining groups(2.5, 2.6mg/kg). The ED50 values for lid and trapezius reflex were lowest in the C/S group(2.9and 4.0mg/kg respectively) and the others had similar values (3.5~3.7mg/kg and 4.7~5.3mg/kg respectively). The ED95 values for trapezius reflex in all patients were distributed between a range of 6.5~9.1mg/kg and this suggests that the usual dose (3~6 mg/kg) is not sufficient to prevent the stress response of tracheal intubation. Also, the results indicate that the dose of thiopental for induction should be reduced because of the increasing sensitivity of the central nervous system with the cesarean section group and the free drug fraction of thiopental in patients with end stage renal disease. Therefore, if a patient with full term pregnancy or renal failure is to be induced with a single injection of thiopental, it is recommended to reduce the rate of injection.
Anesthesia, General*
;
Body Weight
;
Catheters
;
Central Nervous System
;
Cesarean Section*
;
Female
;
Humans
;
Intubation
;
Kidney Failure, Chronic*
;
Pregnancy
;
Reflex
;
Renal Insufficiency
;
Superficial Back Muscles
;
Thiopental*
4.A Survey of the Nutrients and a Price Comparison of Korean Style Full Course Meals: Based on Korean Restaurants in Changwon City and in Luxurious Hotels in Seoul.
Jeong Soon PYUN ; Tae Hee KIM ; Hae Won PARK ; Kyung Hea LEE
Korean Journal of Community Nutrition 2003;8(3):327-339
The objectives of this study were to conduct preliminary research to investigate full course meals in Korean style restaurants in order: i) to analyze the nutrient contents of full course meals per servings, and ii) by analyzing the above, to examine the amount and the quality of the foods served in the full course meals by two different types of Korean style restaurants. A total of 27 restaurants participated in this study, 7 restaurants from the luxurious hotels in Seoul and 20 restaurants from the City of Changwon. A key finding was that restaurant patrons tended to overconsume nutrients as compared to the Korean Recommended Daily Allowance (RDA), and restaurants generated large amounts of food wastes due to the excess food served. Other findings were as follows: 1) Compared with 1/3 or the Korean RDA, all the nutrients were oversupplied. The average nutrient ratios were about 3.7 times higher than 113 of the Korean RDA in calories, about 9 times higher in proteins, 10 times higher in phosphorus, 7 times higher in Vitamin Bl, and 12 times higher in Vitamin E. 2) Seventy-five percent (n = 20) of the restaurants served within the range of thirty to forty dishes, whereas most of the hotel restaurants (70%) served twenty dishes or fewer. 3) The average carbohydrate: protein: fat (CPF) ratio of caloric nutrients was 40:26:34. This study concluded that: i) Korean style full course meals provide too much food, nutrients, and calories, resulting in an over- or unbalanced nutrient intake, and ii) the Korean style full course meals consisted of a high-protein, high-fat and high-caloric intake, which is similar to a westernized caloric nutrient pattern. Such over -or unbalanced nutrient intake could cause chronic degenerative problems such as cancer and cardiovascular disease. These findings indicate that restaurants serving Korean style full course meals should carefully plan their menus in order to provide their customers with balanced meals. They should also be strongly encouraged to play an active role in improving their customers' nutritional status, as well as reducing the restaurants wastage of food. Lastly, further research should be conducted to improve the quality of the menus in Korean restaurants.
Cardiovascular Diseases
;
Gyeongsangnam-do*
;
Meals*
;
Nutritional Status
;
Phosphorus
;
Recommended Dietary Allowances
;
Restaurants*
;
Seoul*
;
Vitamin E
;
Vitamins
5.Two Cases of Total Colon Aganglionosis Involving Small Bowel in Triplet.
Won A PARK ; Hyun Joo KIM ; Kyung Dug MOON ; Hea Kyoung LEE ; Young Hee YU ; Hyun Suk LEE
Journal of the Korean Pediatric Society 1994;37(10):1463-1468
Total or mostly total intestinal aganglionosis is rare and invariably fatal. All patients with aganglionosis involving more than half of the small bowel have died with persistent intestinal obstruction and secondary malnutrition and infection. Recently, we experienced two cases of total colon aganglionosis extending to the middle of the jejunum in triplet. We report the cases with brief review of literatures.
Colon*
;
Humans
;
Intestinal Obstruction
;
Jejunum
;
Malnutrition
;
Triplets*
6.A Study on Health Status of Industrial Workers by Application of the Modified C.M.I..
Joon Yun KIM ; Won Gae CHO ; Chong Kyun LEE ; Yong Chun KIM ; Hea Koun PARK ; Don Kyoun KIM
Korean Journal of Preventive Medicine 1972;5(1):25-35
From May lst to November 30th, 1971, a study was conducted by authors on the health status of industrial workers through applying the modified Cornell Medical Index forwards a total of 4,565 labourers working in Busan City. The obtained results were as follows : 1. The largest number of industries and labourers was in Busanjin Gu, 9 and 2,386 (52.2%), respectively. 2. Total numbers of labourers subjected to the survey were 2,355 (51.6% in male, 2,210(48.4%) in female. 3. By age and sex distribution, the largest was seen with the age group of 25-34, 1,260 in male, otherwise with under the age group of 24, 1,994 in female labourers. 4. The highest average number of complaints by section among all age groups and industries was as follows ; In case of male labourers, textile was the highest with numbering 8.7 (35-39 age group) in the section of physical complaints, in the section of mental and total complaints, food industry was the highest with numbering 8.2 and 16.4, respectively, both under 19 age group, otherwise in case of female labourers, food industry was the highest with numbering 12.3 (physical), 10.3(mental) and 22.7 (total complaints) with all in 20-24 age group. 5. The lowest average number of complaints by section among all age groups and industries was as follows; In case of male labourers, other industry was the lowest with numbering 0.4 (55and over) in the physical, 0.3 (19and under) in the mental and 0.7 (55and over) in the section of total complaints, otherwise incase of female labourers, basic metal was the lowest in the all sections with all in 50-54 age groups.
Busan
;
Cornell Medical Index
;
Female
;
Food Industry
;
Humans
;
Male
;
Sex Distribution
;
Textiles
7.A Study on Health Status of Industrial Workers by Application of the Modified C.M.I..
Joon Yun KIM ; Won Gae CHO ; Chong Kyun LEE ; Yong Chun KIM ; Hea Koun PARK ; Don Kyoun KIM
Korean Journal of Preventive Medicine 1972;5(1):25-35
From May lst to November 30th, 1971, a study was conducted by authors on the health status of industrial workers through applying the modified Cornell Medical Index forwards a total of 4,565 labourers working in Busan City. The obtained results were as follows : 1. The largest number of industries and labourers was in Busanjin Gu, 9 and 2,386 (52.2%), respectively. 2. Total numbers of labourers subjected to the survey were 2,355 (51.6% in male, 2,210(48.4%) in female. 3. By age and sex distribution, the largest was seen with the age group of 25-34, 1,260 in male, otherwise with under the age group of 24, 1,994 in female labourers. 4. The highest average number of complaints by section among all age groups and industries was as follows ; In case of male labourers, textile was the highest with numbering 8.7 (35-39 age group) in the section of physical complaints, in the section of mental and total complaints, food industry was the highest with numbering 8.2 and 16.4, respectively, both under 19 age group, otherwise in case of female labourers, food industry was the highest with numbering 12.3 (physical), 10.3(mental) and 22.7 (total complaints) with all in 20-24 age group. 5. The lowest average number of complaints by section among all age groups and industries was as follows; In case of male labourers, other industry was the lowest with numbering 0.4 (55and over) in the physical, 0.3 (19and under) in the mental and 0.7 (55and over) in the section of total complaints, otherwise incase of female labourers, basic metal was the lowest in the all sections with all in 50-54 age groups.
Busan
;
Cornell Medical Index
;
Female
;
Food Industry
;
Humans
;
Male
;
Sex Distribution
;
Textiles
8.Influence of Clinical and Demographical Variables on Depression, Instrumental Activities of Daily Living, and Cognitive Function in Patients with Parkinson's Disease.
Kyeong Yae SOHNG ; Dong Won CHOI ; Hea Ja PARK
Journal of Korean Academy of Fundamental Nursing 2006;13(2):249-256
PURPOSE: To investigate the influence of clinical and demographical variables on depression, instrumental activities of daily living (IADL), and cognitive function in patients with Parkinson's disease. METHOD: Using a structured questionnaire data were collected from 100 participants registered in the neurology department of C university hospital. Duration and stage of disease, fall history, vision impairment, duration and quality of sleep, orthostatic hypotension, ambulation impairment, and use of walking aid were included in clinical variables. Depression, IADL, and cognitive function were assessed using Kee's GDSSF-K, Cho's scale, and K-MMSE. Collected data were analyzed using the SAS program. RESULTS: The depression score for the participants was 7.78, higher than cut-off score(5). Participants who were male, living with spouse, above high school education, high economic status, with no vision impairment, and no ambulation impairment revealed high cognitive scores. Average IADL score were significantly higher for participants who were male, who had high economic status, low stage of disease, and no ambulation impairment. Depression IADL & cognitive function scores were significantly different according to ambulation impairment. Scores for ADL and cognitive function were positively correlated. CONCLUSION: It is recommended that make programs for patients with Parkinson's disease, clinical and demographic variables should be considered according to their individual needs.
Activities of Daily Living*
;
Cognition
;
Depression*
;
Education
;
Humans
;
Hypotension, Orthostatic
;
Male
;
Neurology
;
Parkinson Disease*
;
Surveys and Questionnaires
;
Spouses
;
Walking
9.Clinical Characteristics of Methylphenidate Use in Korean Children and Adolescents with Autism Spectrum Disorder : A Retrospective Study.
Jin Park PARK ; Jong Il LEE ; Hea Kyung JHIN ; Hae Ji MIN ; Jun Won HWANG ; Yeni KIM
Journal of the Korean Academy of Child and Adolescent Psychiatry 2012;23(3):154-160
OBJECTIVES: The purpose of this study was to investigate clinical characteristics of children and adolescents with autism spectrum disorders (ASDs) using methylphenidate (MPH). METHODS: Retrospective review of the charts of 79 children and adolescents with ASDs, who visited the Department of Child and Adolescent Psychiatry of Seoul National Hospital, from July 2010 to July 2011, was conducted. Changes in illness severity and improvement were measured using the Clinical Global Impression-Severity of illness (CGI-S) and Clinical Global Impression-Improvement (CGI-I) Scales. RESULTS: We found that MPH was prescribed in 23 (29.1%) children and adolescents. Of the 23 patients on MPH, 4 patients (17.4%) were on MPH monotherapy and 18 patients (78.3%) were using risperidone concomitantly. MPH was prescribed primarily for symptoms of hyperactivity and impulsivity in ASDs patients. The mean dosage of MPH was 26.2+/-11.1mg/day and mean duration of treatment was 31.9+/-28.7 months. Mean CGI-S score improved significantly from baseline to endpoint (from 5.4+/-0.6 to 4.1+/-0.9 ; p<.01). MPH was reported to be effective in 17 patients (17/23, 73.9%), and 10 patients (10/23, 43.5%) reported side effects. Side effects included decreased appetite (4/23, 17.4%), tic (2/23, 8.6%), sleep disturbances (2/23, 8.6%), headache (1/23, 4.3%) and irritability (1/23, 4.3%). CONCLUSION: The results of this study demonstrate that MPH may be used effectively and safely in children and adolescents with ASDs with hyperactivity and impulsivity. Future controlled trials are needed to confirm these findings.
Adolescent
;
Adolescent Psychiatry
;
Appetite
;
Autistic Disorder
;
Child
;
Autism Spectrum Disorder
;
Headache
;
Humans
;
Methylphenidate
;
Phenazines
;
Retrospective Studies
;
Risperidone
;
Tics
10.Isolation of Trichophyton rubrum from Diabetic Foot Ulcers of 4 Patients.
Weon Ju LEE ; Kyung Hea PARK ; Yong Hyun JANG ; Seok Jong LEE ; Do Won KIM
Korean Journal of Medical Mycology 2014;19(1):9-12
Trichophyton rubrum is a common cause of superficial dermatophytosis in humans, such as tinea pedis, tinea unguium, tinea corporis and tinea cruris. T. rubrum usually attaches to keratin of the epidermis and uses it as a source of nutrients. Therefore, isolation of T. rubrum from non-keratinous skin, such as ulcer, is very rare. We describe 4 patients with T. rubrum-infected diabetic foot ulcer.
Diabetic Foot*
;
Epidermis
;
Humans
;
Onychomycosis
;
Skin
;
Tinea
;
Tinea Pedis
;
Trichophyton*
;
Ulcer*