China ; Cone-Beam Computed Tomography ; Dental Stress Analysis ; Humans ; Imaging, Three-Dimensional ; Malocclusion ; diagnosis ; etiology ; therapy ; Orthodontics ; manpower ; trends ; Orthodontics, Corrective ; methods

Objective To discuss the utility of MRI in evaluating arrhythmogenic right ventricular cardiomyopathy(ARVC).Methods Nine patients of ARVC who received treatment in our hospital from January 2005 to May 2008,were retrospectively analyzed.They all underwent MRI by using GE signa 1.5 Tesla CV/I MR system.White blood technique(Fast cine sequence) were performed in short axis view,four-chamber view,and long axis view of two ventricles.Black blood techniques(Double IRFSE and Triple IRFSE) were performed in short axis view and long axis view of the right ventricle.Results MRI displayed thinning of the right ventricular(RV) wall(9 cases),dilatation of the RV(8 cases),fat signal intensity of the RV wall in DIRFS and irregular insula or continuity breaking in TIRFSE(3 cases),dilatation of the left ventricle(LV)(2 cases),a bit thickening of ventricular septum(1 case),enlargement of the outflow of the RV(2 cases),and ventricular wall aneurysm formation(2 cases).Their positions involved apex of the right ventricle(6 cases),facies diaphragmatica(4 cases),anterior ventricle(4 cases),infundibulum(4 cases) and the papillary muscle of the RV(1 case).Conclusion Cardiac MRI is the most specific and sensitive examination technique in diagnosing of ARVC,which can present structural and functional changes and the quality,degree,range of the disease.We recommend cardiac MRI if ARVC is suspected.

Objective To study the feasibility of transplanting autologous venous endothelial cells, as the liner, to the allogenic vein and to investigate the patency rate after such transplantation. Methods Autologous endothelial cells were gained after the administration of 0.2% collagenase and the centrifugalization of the enzyme liquid. The cells were not cultivated in a 60 ml plastic culture until the presence of the second generation. The cultivated cells were confirmed as endothelial cells by factor Ⅷ related antigen. The multiplied cells were lined in vitro onto the luminal surface of allogenic vein that was disposed by freeze-drying and radiation. The orthotopic transplantation of autologous venous endothelial cells was performed after the 9-day incubation. Results (9.47?0.35)?10~6 endothelial cells were obtained after the cultivation. Three hours after cell seeding, the luminal surface of allogenic vein was covered with vast endothelial cells but still had not formed an intact endomembrane. On day 9, the luminal surface was covered with a continuous endothelial monolayer and the arrangement and the shape of the cells all showed the perfect condition of endothelial cells. Eight weeks later, all the transplanted veins kept unobstructed. Conclusion The approach of lining allogenic vein with autologous endothelial cells in vitro may keep the vein unobstructed in the long term.

Objective To summarize analysis in elderly patients with type 2 diabetes mellitus with cerebral microvascular lesion with diabetes pill in combination with metformin on patients after treatment the blood viscosity, the effects of cognitive dysfunction.Methods Our hospital during the period of July 2014 to September 2016 received 100 cases of elderly patients with type 2 diabetes mellitus with cerebral microvascular lesions, according to the random allocation method divided into observation group(50 cases) and control group(50 cases) and control group using metformin treatment, the observation group USES the diabetes pill metformin treatment, treatment effect of two groups of patients and related indicators for comparative analysis.Results After treatment the cognitive function score and blood viscosity related indicators, statistically significant differences between observation group and control group.Conclusion Elderly patients with type 2 diabetes mellitus with cerebral microvascular lesions in clinical application in diabetes, pill metformin, help to improve the patient's cognitive dysfunction, improve the patient's blood viscosity, promote the prognosis of patients, is worthy of popularization and application.

BACKGROUND:Biomaterial combined with stem cels is revealing a bright future in bone tissue regeneration in orthopedic surgery. Induced pluripotent stem cels have better cel sources and characteristic, which have become a hotspot of stem cel field. OBJECTIVE:To review the research history, preparation method, cel characteristics of induced pluripotent stem cels and the research developments in orthopeadic surgery so far. METHODS:A computer-based search of CNKI and PubMed was performed for articles about induced pluripotent stem cels and their applications in the field of orthopeadic surgery published from 1999 to 2014. Typical and creative research achievements were enroled in result analysis. RESULTS AND CONCLUSION: Studies have shown that induced pluripotent stem cels have a potential application prospect in bone tissue regeneration, and they also show a satisfying biocompatibility with various scaffold materials, in which, the induced pluripotent stem cels can maintain a good osteogenetic potential. Detection methods and smal-molecule compounds have been discovered gradualy for cartilage regeneration. But how to effectively induce the chondrogenic differentiation of induced pluripotent stem cels and to realize the clinical applications need further research.

This review firstly introduces sixty h type indices which are categorized in order to overcome the drawbacks of the Hirsch index,especially the advantages and limits of the h type indices when comparing with h index.Moreover,the review gives a list to show the main characteristics of h type indices.Lastly,some illustrative researches are shown to present the applicability of some h type indices.

Objective To study effects of the intrathymic injection of allohepatic cells on intestinal allograft.Methods Adult male DA and PVG rats,7-9 week old,were used as donors and recipients,respectively.The ectopic small howel transplantations were performed one week after intrathymic injection of hepatic cells without use of any immunosuppressants.The surgical procedures were carried out in a such manner that portal vein was anastomosed with 1eft renal vein by the cuff,aorta was anastomosed with superior mesenteric artery with its aortic patch.Results The donor liver ceils could survive in the recipient thymus for 3 weeks.The small intestinal allograft showed severe rejection and donor died one week after intrathymic injection of hepatic cells,but the hepatic cells could survive within the thymus at this time.Conclusion The intrathymic injection of allohepatic cells could not induce immune tolerance of the recipient to the same donor small intestinal graft.

Objective To study the incidence,risk factors and clinical features of patients with acute hepatic dysfunction induced by sepsis. Methods One hundred and sixty patients with sepsis were assigned to two groups according to liver function: sepsis group and acute hepatic dysfunction group. Logistic regression analysis was used to study the risk factors.The comparison of plasma endothelin-1 ( ET-1 ) and sepsis-related organ failure assessment (SOFA) score between two groups was carried out.Results Of 160sepsis patients,25 (15.6％) patients were subjected to acute hepatic dysfunction induced by sepsis.Logistic regression analysis showed that long-term indulgence in wine drunk (OR =4.102,95％ CI 1.288 -13.063 ),history of cardiac insufficiency ( OR =4.109,95％ CI 1.352 - 12.493) and hypotension ( OR =5.833,95％ CI:1.712 - 19.868 ) were the significant risk factors.Though oxygenation index ( PaO2/FiO2),platelet (PLA) and Glasgow coma scale (GCS) were not different between two groups,the total bilirubin (Tbil),direct bilirubin (Dbil),creatitine (Cre),range of blood glucose variation (Rglu),lactic acid (Lac),plasma ET-1and SOFA score in acute hepatic dysfunction group were higher than those in sepsis group. Mortality rate in acute hepatic dysfunction group was higher than that in sepsis group.Conclusions Long-term drunk,history of cardiac insufficiency and hypotension are the risk factors in acute hepatic dysfunction induced by sepsis.Elevated arterial Lac and plasma ET-1 levels,and higher SOFA score in acute hepatic dysfunction group suggest poor prognosis.

Objective To investigate the incidence, risk factors and drug-resistance of Pseudomonas aeruginosa infection in intensive care unit (ICU). Methods Totally 171 patients with sepsis admitted in ICU were enrolled. Pathogenic bacteria culture and antimicrobial susceptibility tests were performed. SPSS10. 0 software was used for Logistic regression analysis of the risk factors. Results Pseudomonas aeruginosa infection was confirmed in 37 patients, and 45 strains of Pseudomonas aeruginosa were isolated. Logistic regression revealed that recent antibiotics use ( OR = 4. 291 , 95% CI: 1. 727-10. 662) , length of ICU stay (OR = 1.117, 95% CI: 1.058-1. 181) , mechanical ventilation (OR = 3.400, 95% CI: 1.348-8.579) and central venous catheterization (OR =3. 339, 95% CI: 1.322-8.434) were independent risk factors of Pseudomonas aeruginosa infection. The resistance rate of cefotaxime was the highest (68.9%) and 18 strains (40%) were multidrug-resistant. Conclusions Pseudomonas aeruginosa infection is common in ICU and it is usually multidrug resistant. The rational use of antibiotics and aseptic technique of invasive catheterization are important for the prevention of Pseudomonas aeruginosa infection.

Objective To explore effective coping style of targeted psychodrama on teenager offenders.Methods Targeted psychodrama intervention procedures were designed.60 teenagers selected from juvenile detention jail were randomly divided into experimental group and control group.Psychodrama intervention was applied to the experimental group to test the changes of the two groups before and after the intervention using simplified coping style questionnaire.Results Before the intervention,the positive coping style level of the experimental group was 1.40 ± 0.42,the negative coping style level was 2.19 ± 0.32; after the intervention,the positive coping style level of the experimental group was 2.13 ± 0.36,the negative coping style level was 1.77 ±0.30.The difference of the experimental group's positive response and the negative response were significant before and after the intervention(t =-6.223,P＜ 0.01; t =9.749,P＜0.01).The difference of the control group's positive response and the negative response were not significant (P ＞ 0.05).Conclusion Psychodrama intervention has a positive effect on the criminal teenagers coping styles,and it can improve their social adaptability.