1.Clinical research on application of adjustable sutures in glaucoma filtering operation
International Eye Science 2014;(10):1868-1870
AIM:To discuss the application effect of adjustable sutures in glaucoma filtering operation after trabecular resection.
METHODS: Seventy-eight cases ( 101 eyes ) suffered from glaucoma were randomly divided into two groups, observation group and control group. Thirty-nine cases ( 51 eyes ) in the observation group underwent trabeculectomy with adjustable sutures, the control group (39 cases, 50 eyes) only adopted trabeculectomy.RESULTS: Compared Preoperative IOP in two groups, the difference was not statistically significant (P>0. 05). After 6mo, IOP were decreased compared with preoperative in two groups, and that in observation group was lower than control group, the difference was statistically significant ( P < 0. 05 ). Six months after operation, there were 1 eye with shallow anterior chamber Ⅰ and 2 eyes with non- functional bleb in observation group, and the complication rate was 5. 9%. While there were of 6 eyes with shallow anterior chamber, in which 4 eyes at gradeⅠ, each one at gradeII and Ⅲ. Non-functional blebs in 5 eyes and a scleral flap adhesion complications rate in the control group was 24. 0%, significantly higher than that in the observation group, the difference was statistically significant ( P<0.01).
CONCLUSION: The adjustable sutures combined with trabeculectomy for glaucoma can significantly reduce the postoperative complications. The curative effect is exact and clinically applicable.
3.Expression of muscarinic cholinergic receptor 3 in small cell lung cancer and its clinical sig-nificance
Hua HE ; Ailing MA ; Shuxiang ZHANG
Chinese Journal of Clinical and Experimental Pathology 2014;(11):1237-1241
Purpose To investigate the expression of muscarinic cholinergic receptor 3 (M3R) in small cell lung cancer (SCLC) and the correlation between it and clinical characteristics of SCLC. Methods The M3R expression was examined in 60 SCLC patients ad-mitted using immunohistochemistry. The patients were evaluated by clinical history, physical examination and chest CT. Survival time was got through telephone follow-up. Results The M3R expression in primary SCLC tissues was higher than that in normal lung tis-sues. The M3R expression had no difference between limited-disease and extensive-disease of SCLC. There was no correlation between M3R expression and age, gender, lymph node metastasis. The M3R expression was significantly correlated with smoking history. The survival time of M3R negative patients was longer than that of M3R positive patients in Kaplan-Meier survival curve. Conclusion The M3R expression in primary SCLC tissues was higher than that in normal lung tissues. M3R expression had some correlation with prog-nosis of SCLC patients.
4.Design of new multi-channel EEG signal acquisition system
Dongjun XU ; Weixing HE ; Hua ZHANG
Chinese Medical Equipment Journal 1993;0(06):-
A new multi-channel EEG signal acquisition system,which adopts Cypress's EZ-USB FX2 series USB as its micro-controller,is presented in this paper.The system employs AD620 and OP07 at the pre-amplifying stage and the following two amplifying stages respectively.Universal Series Bus(USB) technology is used to realize the real-time recording,displaying and tele-monitoring of EEG signal,which can also be stored in CF card after compression.The USB software developing tool is WinDriver.
5.Zinc and IL-1beta concentration in serum and cerebrospinal fluid in children with febrile seizure.
Chao-Gui ZHANG ; Chang-Hua QU ; Hua YANG ; Wan-Hong LIU ; Xiao-Hua HE
Chinese Journal of Applied Physiology 2013;29(4):344-345
Child, Preschool
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Female
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Humans
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Infant
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Interleukin-1beta
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blood
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cerebrospinal fluid
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Male
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Seizures, Febrile
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blood
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cerebrospinal fluid
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Zinc
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blood
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cerebrospinal fluid
6.A preliminary study on the toxin of earthworm and the methods to take it off
Zuxun ZHANG ; Liming HE ; Peilan YU ; Dianer YANG ; Hua LIU
Chinese Journal of Biochemical Pharmaceutics 2001;22(3):112-113
Purpose The source of earthworm toxin, its ingredients and the methods to take it off were studied.Methods The irritable secretor was dialyzed, and then examined by UV-Vis spectrum instrument.The proteins was analyzed with electrophoresis. The toxicity was tested in vivo.Results The proteins of irritable secretor 0.242mg/kg iv cause a mouse to death.Many bands were separated from the proteins with SDS-PAGE, among which two kinds were the principal. Even with different stimulus the secretor of earthworm was identical in ingredients.Conclusion The results demonstrated that the earthworm proteins of irritable secretion had toxicity and the toxin could be removed from earthworm by adding NaCl or 40V electricity.
7.Effects of genistein on expressions of jak1 kinase and inteleukin-4 in lung of guinea pigs with bronchial asthma.
Xiu-feng ZHANG ; Zhen-hua HE ; Xiao-wu TAN
Chinese Journal of Applied Physiology 2009;25(3):328-348
Animals
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Asthma
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drug therapy
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metabolism
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Genistein
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pharmacology
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therapeutic use
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Guinea Pigs
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Interleukin-4
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genetics
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metabolism
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Janus Kinase 1
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genetics
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metabolism
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Lung
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metabolism
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Male
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Protein Kinase Inhibitors
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pharmacology
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therapeutic use
8.Comparative study of dual-source MDCT signs with pathology in renal cell carcinoma
Hua HE ; Bofei LIU ; Yulin GUO ; Ting LI ; Xiaobiao ZHANG
Journal of Practical Radiology 2014;(5):822-825
Objective To analyze relationship between dual-source MDCT and pathology in renal cell carcinoma.Methods 129 patients with pathology were proved renal cell in our hospital from 2009 to 2012.According to the latest 2004 WHO pathological classification,CT features of renal carcinoma were compared with surgical and pathological results.Results The enhancement de-gree of lesions on contrast CT was correlated to the modal of renal malignant cells’ranking.There was no certain correlation be-tween integrity on the edge of the tumor in CT and pathological tumor capsular.The short-hair sign surrounding the margin of tumor strongly indicated renal capsule invasion (P <0.01).Agreement between CT-Robson staging and surgical-pathologic staging was good(Kappa=0.75).Conclusion The CT finding of renal cell carcinoma is correlated with tumor cell characteristic and inter-nal structure.Dual-source MDCT has important clinical value in the diagnosis of renal cell carcinoma.
9.Affective of EGR2 expression in Schwann cells line exposed in high glucose
Hua ZHANG ; Yanli LIU ; Xueqin HE ; Xinghui LIU
International Journal of Laboratory Medicine 2014;(8):945-946
Objective To investigate the effects of different glucose concentration on EGR2 protein expression in Schwann cells . Methods Schwann cells were cultured in different glucose concentrations ,and they were divided into two groups ,normal glucose concentration (5 .5 mmol/L ,N group) and high glucose concentration(25 mmol/L ,H group) .Immunocytochemistry and Western blot were used to study EGR2 expression .Results The expression of EGR2 protein was higher in H group than that in N group the difference was statistically significont (P<0 .05) .Conclusion High glucose can lead to EGR2 protein upregulate in Schwann cells ,and EGR2 maybe one of the reasons of diabetic neuropathy .
10.MRI Manifestation of Temporomandibular Joint after Trauma
Hua WANG ; Xiaoying WANG ; Yi ZHANG ; Dongmei HE ; Xuexiang JIANG
Journal of Practical Radiology 1991;0(03):-
Objective To investigate MRI manifestations of temporomandibular joint trauma,emphasized on the displacement and deformation of the meniscus.Methods Thirteen patients with TMJ trauma were examined by MRI with 3-inch dual surface coils.T1WI and T2WI images in oblique sagittal and coronal plane were acquired in both closed-and open-mouth positions.Results Twenty(20/26,76.9%) joints had condylar fractures.Nineteen(19/20,95%) discs in 12 patients displaced anteromedially with the condylar fragments,six(6/20,30%) discs showed distortion and deformation.The other one patient had unilateral condylar fracture companied with avulsion and lateral dislocation of ipsilateral disc(1/20,5%),and the opposite disc also showed slight anterior displacement.Effusion was observed in 12(12/20,60%) joints with condylar fractures.The location of the discs didn't show obvious change between closed-and open-mouth positions.Conclusion MRI is an effective method for demonstrating TMJ injuries,and is useful for detecting the changes of morphology and position of the discs.