The author reviewed the toxicity and complications of tumor radiotherapy and chemotherapy from the aspects of etiology,pathogenesis and differential treatment of TCM

Objective To compare the clinical effect of different treatment methods for the patients with great saphenous vein varicosity.Methods 140 patients with great saphenous varicose veins were selected,and according to random number table method they were divided into observation group and control group,70 cases in each group.The control group was given conventional stripped surgery,the observation group adopted high ligation joint int-racavitary laser treatment.The clinical effects of the two groups were compared.Results The operating time,intraop-erative blood loss,postoperative length of hospital stay,postoperative recurrence rate of the observation group were (51.32 ±4.97)min,(40.03 ±9.67)mL,(6.77 ±1.14)days,4.29%,respectively,which of the control group were (72.45 ±8.79)min,(108.68 ±17.75)mL,(11.69 ±2.68)days,20.00%,there were statistically significant differ-ences between the two groups(t =17.507,28.415,14.134,χ2 =8.101,all P <0.05).The incidence rate of postop-erative complications of the observation group was 4.29%,which of the control group was 14.29%,there was statisti-cally significant difference between the two groups(χ2 =4.155,P <0.05).The intervention pain score,the quality of life score of the observation group were (1.46 ±0.54)points,(90.04 ±9.77)points,which of the control group were (2.67 ±1.15)points,(78.61 ±6.82)points,there were statistically significant differences between the two groups (t =7.968,8.026,all P <0.05).Conclusion High ligation joint intracavitary laser in the treatment of great saphe-nous varicose veins is superior to the traditional operation method in operation time,intraoperative hemorrhage,length of hospital stay,and complications,and it can effectively relieve patients'pain and improve the quality of life.

Recent developments on separation and analysis of bacterial cells by capillary electrophoresis are reviewed. Based on bacterial surface characterization, capillary electrophoresis technique can be utilized for rapidly identify and quantify intact bacteria and microbes at a certain phase. The microbe-molecule interactions can also be described. The separation of microbes that can not be cultured in lab appears to be possible by this method. It makes profound effects on separation science and microbiology to establish capillary electrophoresis procedure for the separation and analysis of bacterial cells.

Forty-four guinea-pigs were sensitized by intramuscular inoculation with the same amount (0.8ml) of 5% egg albumin in water. 3 weeks after sensitization, the animals were rondomly divided into 1 groups (group J as control; group II given small dose of piperitone 0.08ml/ 100g body weight; group J given large dose of piperitone 0.12ml/100g body weight; group IX given promethazine 2.5mg 100g body weight) and subjected to anaphylactic insult by intra-cardiac injection of 1ml of 5% egg albumin in water under the protection of different dosege of piperitone, a terpene from cymbopogon distans. given intramuscularly. Results of the experiment indicates that piperitone had significant dose-effect relation protective effect against the anaphylactic insult on the guinea-pigs and suggests that piperitone might be used clinically for the treatment of asthma

Objective: To establish a HS CGC method for the analysis of residual petroleum ether (60～90?C) in Kanglaite Capsules.Methods: Headspace sampling, a fused silica analytical column with cross linked 95% dimethyl and 5% diphenyl siloxanes station phase (30m?320?m?0.25?m), column temperature at 40?C, a linear velocity of about 19 cm per second, FID detector.Results: The average recovery is 97.2% (RSD=2.87%, n=5). The minimal detection limit is 2.65?10 -8 g?mL -1 (signal/noise=1.3).Conclusion: The method is simple and accurate, and can be used as a control method for the residual organic solvent in the capsules.

Objective:To detect the changes on the ratio of T lymphocyte subgroup and immunoglobulin(Ig) in peripheral blood of patients with Primary extranodal lymphoma(PENL).Methods:The peripheral blood T lymphocyte subgroup ratio and immunoglobulin(Ig) complement C3,C4 content were detected by Flow Cytometry(FCM) and Immunoturbidimetry.Results:The numbers of CD3,CD4 or CD8 was lower(P

Objective To explore the clinical efficacy of combination therapy with promethrin and gliclazide sustained-release tablets in the treatment of obese patients with type 2 diabetes mellitus with poor blood glucose control. Methods Selected from December 2015 to March 2017 in our hospital treated 96 cases of insulin treatment of poor blood glucose control in obese patients with type 2 diabetes, were randomly divided into study group and control group, 48 cases in each group.The study group were treated with Novolin 70/30(Novolin 30R)combined with Gliclazide Sustained-release Tablets,while the patients in control group were treated with Novolin 30R combined with repaglinide. Results The decrease of FBG, 2h PG, HbAlc, HOMA-IR and the increase of HOMA-IS in the study group were better than those in the control group (P<0.05).There was no significant difference in BMI between the two groups after treatment and BMI in the control group was significantly higher than that before treatment (P<0.05),CRP was not statistically significant before treatment.Conclusion The application of Novolin 30R and Gliclazide Sustained-release Tablets after treatment can make the use of insulin alone poor glycemic control in obese patients with type 2 diabetes have more desirable clinical efficacy,is conducive to ensuring the safety and effectiveness of drugs.

Autophagy is an important pathway in the body to remove damaged cell organelles and dysfunctional proteins to maintain protein equilibrium and intracellular homeostasis by the lysosomal system .As a degenerative disease of central nervous system , the main feature of Alzheimer ’ s disease is abnormal protein aggregation .However , the role of autophagy in the pathogenesis of Alzheimer ’ s disease is not fully clear yet .The aim of this paper is to take β-amyloid peptide as a starting point to explore the relationship between autophagy and β-amyloid peptide in the pathogenesis of Alzheimer’s disease.

Objective To compare the efficacy of Shaaban and low molecular weight heparin in the prevention and treatment of deep venous thrombosis of lower extremity after knee replacement. Methods January 2011 to 2013 year in January in our hospital 120 cases of knee joint replacement patients as the research object, divided into observation group and control group, the observation group were treated by oral anticoagulant treatment of Lee Shaaban, the control group by subcutaneous injection of low molecular weight heparin treatment than patients were compared between the two groups after deep vein thrombosis the incidence of 14d after treatment, adverse reactions and blood coagulation indexes in patients with drug. Results The observation group of patients with deep vein thrombosis rate was 1.67%, significantly lower than the control group 13.34%, the difference was statistically significant (P<0.05); no statistical significance in two groups of patients after the treatment of 14d PLT, APTT and PT level difference; the observation group of patients with drug adverse reaction incidence rate was 5%. The 13.34% was significantly lower than the control group, the difference was statistically significant (P<0.05). Conclusion Compared with low molecular weight heparin, the incidence of deep vein thrombosis is lower, the adverse reactions are less, and the curative effect is more obvious after applying Shaaban's knee replacement.

Thalassemia is inherited hemolytic anemia caused by globin production disorder,clinically known as beta thalassemia and alpha thalassemia resulted from beta and alpha chain synthesis disorder.Significant anemic clinical manifestations are observed in intermediate -level and severe -level patients with the 2 types of anemia, affecting greatly the growth and life quality of children patients who need blood transfusion to stay alive.The incidence rate of thalassemia is as high as 7% -20% in South China,so the prevention and standaridized treatment of thalasse-mia and the management over target population draw more attention.This paper is a review on the latest development of blood transfusion,chelation therapy,health education,birth intervention for thalassemia.