1.Reviews of TCM prevention and treatment on the toxicity and complications of tumor radiotherapy and chemotherapy
International Journal of Traditional Chinese Medicine 2010;32(1):79-80
The author reviewed the toxicity and complications of tumor radiotherapy and chemotherapy from the aspects of etiology,pathogenesis and differential treatment of TCM
2.Separation and Analysis of Bacteria by Capillary Electrophoresis
Microbiology 1992;0(03):-
Recent developments on separation and analysis of bacterial cells by capillary electrophoresis are reviewed. Based on bacterial surface characterization, capillary electrophoresis technique can be utilized for rapidly identify and quantify intact bacteria and microbes at a certain phase. The microbe-molecule interactions can also be described. The separation of microbes that can not be cultured in lab appears to be possible by this method. It makes profound effects on separation science and microbiology to establish capillary electrophoresis procedure for the separation and analysis of bacterial cells.
3.Effect of Brain HQ visual training on memory function in lymphoma patients with chemotherapy-related cognitive impairment
Chinese Journal of Practical Nursing 2021;37(6):406-410
Objective:To explore the effect of Brain HQ visual training on memory function in lymphoma patients with chemotherapy-related cognitive impairment.Methods:From January to December 2019, 39 hospitalized patients in lymphoma department were selected as the research object, and divided into intervention group (19 cases) and control group (20 cases) by the order of admission. The control group was given routine nursing, and the intervention group was given Brain HQ visual training. The two groups of patients used the auditory learning test to evaluate the memory function effect at the time of enrollment, after 2 cycles and 4 cycles.Results:After 2 cycles intervention, there were no statistically significant indicators for immediate recall, short-term delayed recall, long-term delayed recall, re-recognition, and correct recall ( t values were 0.575-1.248, P> 0.05); After 4 cycles of chemotherapy, the three indicators of long-term delayed recall, recognition and correct recall of the intervention group were (6.00±1.59), (9.05±1.81), (36.00±4.27) points, while (4.75±1.55), (8.05±1.73), (32.85±3.59) points of the control group, there was a statistically significant difference in ( t values were 3.384, 2.373, 3.010, P < 0.05); repeated measures analysis of variance showed The total indicators of immediate recall, short-term delayed recall, long-term delayed recall, recognition and correct recall were not statistically significant in both groups ( F values were 0.329-1.462, P>0.05). Conclusion:The effect of Brain HQ visual training on memory function are not clear, but with the change of intervention time, memory indicators are constantly improving, Brain HQ visual training has certain practicability.
4.THE PROTECTIVE ACTION OF PIPERITONE IN ANAPHYLACTIC SHOCK OF THE GOINEA--PIG
Journal of Chongqing Medical University 1986;0(02):-
Forty-four guinea-pigs were sensitized by intramuscular inoculation with the same amount (0.8ml) of 5% egg albumin in water. 3 weeks after sensitization, the animals were rondomly divided into 1 groups (group J as control; group II given small dose of piperitone 0.08ml/ 100g body weight; group J given large dose of piperitone 0.12ml/100g body weight; group IX given promethazine 2.5mg 100g body weight) and subjected to anaphylactic insult by intra-cardiac injection of 1ml of 5% egg albumin in water under the protection of different dosege of piperitone, a terpene from cymbopogon distans. given intramuscularly. Results of the experiment indicates that piperitone had significant dose-effect relation protective effect against the anaphylactic insult on the guinea-pigs and suggests that piperitone might be used clinically for the treatment of asthma
5.Determination of Residual Petroleum Ether (60~90?C) in Kanglaite Capsules by CGC
Chinese Traditional Patent Medicine 1992;0(02):-
Objective: To establish a HS CGC method for the analysis of residual petroleum ether (60~90?C) in Kanglaite Capsules.Methods: Headspace sampling, a fused silica analytical column with cross linked 95% dimethyl and 5% diphenyl siloxanes station phase (30m?320?m?0.25?m), column temperature at 40?C, a linear velocity of about 19 cm per second, FID detector.Results: The average recovery is 97.2% (RSD=2.87%, n=5). The minimal detection limit is 2.65?10 -8 g?mL -1 (signal/noise=1.3).Conclusion: The method is simple and accurate, and can be used as a control method for the residual organic solvent in the capsules.
6.Progress on individual therapy of colorectal cancer
Basic & Clinical Medicine 2010;30(1):97-99
Chemotherapy plays an important role in advanced colorectal cancer. Patients may show various clinical response to selection different drugs. The importance of individual therapy based on pharmacogenomics has been emphasized in cancer therapy. To explore the individual therapy of colorectal cancer, the progress of molecular markers which influence the efficacy of anti-tumor drugs containing fluorouracil, oxaliplatin, CPT-11, monoclonal antibody drugs is reviewed in this article.
7.Standardized management of thalassemia
Chinese Journal of Applied Clinical Pediatrics 2017;32(3):168-172
Thalassemia is inherited hemolytic anemia caused by globin production disorder,clinically known as beta thalassemia and alpha thalassemia resulted from beta and alpha chain synthesis disorder.Significant anemic clinical manifestations are observed in intermediate -level and severe -level patients with the 2 types of anemia, affecting greatly the growth and life quality of children patients who need blood transfusion to stay alive.The incidence rate of thalassemia is as high as 7% -20% in South China,so the prevention and standaridized treatment of thalasse-mia and the management over target population draw more attention.This paper is a review on the latest development of blood transfusion,chelation therapy,health education,birth intervention for thalassemia.
8.Effect of Kangfuxin Liquidon on gingiva groove liquid IL-1β, PGE2, sICAM-1in fixed orthodontic patients with gingivitis
Chinese Journal of Biochemical Pharmaceutics 2017;37(1):78-80
Objective To analyze the effect of Kangfuxin Liquidon on gingiva groove liquid interleukin 1β(IL-1β), prostaglandin E2 (PGE2), soluble adhesion molecule-1 (sICAM)in fixed orthodontic patients with gingivitis. Methods 96 cases of patients with fixed orthodontic gingivitis consult the draw method were divided into control group and experimental group, 48 cases in each group. The control group were treatedby gums clean, experimental group based on the control group were treattedby Kangfuxin Liquidon. The IL-1β, PGE2, sICAM-1 levels, periodontal status, the grade of swelling and pain, the clinical curative effect were compared between two groups. Results After treatment, the IL-1β, PGE2, sICAM levels of experimental group were lower than the control group (10.54±1.41) ng/L vs.(11.85±1.71)ng/L, (284.62±35.21) ng/L vs.(314.65±39.48)ng/L, (150.49±18.11) μg/L vs.(162.83±20.26) μg/L,the differences were statistically significant (P<0.05).The periodontal status, swelling and pain grading ofexperimental group were better than control group (P<0.05). Theeffective rate of experimental group was higher than the control group (95.83%vs.79.17%) (P<0.05). Conclusion Kangfuxin Liquidon can reduce fixed orthodontic patients with gingivitis gingiva groove IL-1β, PGE2, sICAM-1 levels, improve the periodontal status, relieve swelling and pain, improve the clinical curative effect.
9.Comparison of the clinical effect of different treatment methods for the patients with great saphenous vein varicosity
Chinese Journal of Primary Medicine and Pharmacy 2016;23(2):208-211
Objective To compare the clinical effect of different treatment methods for the patients with great saphenous vein varicosity.Methods 140 patients with great saphenous varicose veins were selected,and according to random number table method they were divided into observation group and control group,70 cases in each group.The control group was given conventional stripped surgery,the observation group adopted high ligation joint int-racavitary laser treatment.The clinical effects of the two groups were compared.Results The operating time,intraop-erative blood loss,postoperative length of hospital stay,postoperative recurrence rate of the observation group were (51.32 ±4.97)min,(40.03 ±9.67)mL,(6.77 ±1.14)days,4.29%,respectively,which of the control group were (72.45 ±8.79)min,(108.68 ±17.75)mL,(11.69 ±2.68)days,20.00%,there were statistically significant differ-ences between the two groups(t =17.507,28.415,14.134,χ2 =8.101,all P <0.05).The incidence rate of postop-erative complications of the observation group was 4.29%,which of the control group was 14.29%,there was statisti-cally significant difference between the two groups(χ2 =4.155,P <0.05).The intervention pain score,the quality of life score of the observation group were (1.46 ±0.54)points,(90.04 ±9.77)points,which of the control group were (2.67 ±1.15)points,(78.61 ±6.82)points,there were statistically significant differences between the two groups (t =7.968,8.026,all P <0.05).Conclusion High ligation joint intracavitary laser in the treatment of great saphe-nous varicose veins is superior to the traditional operation method in operation time,intraoperative hemorrhage,length of hospital stay,and complications,and it can effectively relieve patients'pain and improve the quality of life.
10.Effect of concanavalin A on mouse islet transplantation
Chinese Journal of Pathophysiology 1986;0(01):-
To test whether Con A has antirejection effect on mouse islet allograft, 600-700 handpicked islets of C57BL/6 mice was transplanted beneath the kidney capsule of the streptozotocin induced diabetic BALB/C recipients. In control group the mean survival time (MST) of the grafts was 14.1?2.4 days. Treatment with Con A significantly prolong the MST of the islet allografts. In group with Con A treatment of the donor islets prior to the transplantation the MST was 25?5.4 days. The MST increased sigificantly after ip injection of Con A to recipient mice. The combined treatment of islet and recipient with Con A resulted in a prolongation of MST to 25.2?4.4 days. The experiments concerning the mechanisms of the antirejection effect of Con A showed that Con A was able to combine with the islet cell membrane well masking perhaps the histocmpatibility antigen. Furthermore the lymphocytes of mice after i. p Con A injection suppressed the lymphocyte proliferation reaction of the svnergic mice to mitogen.