Objective To study the giant invasive pituitary tumor neuroendoscopic operation indications,operation excision,risk aversion,and the operation skills.Methods The clinical data of 7 patients with giant invasive pituitary tumor among of endoscopic transsphenoidal surgery 61 cases of neurological patients with pituitary tumors were analyzed retrospectively.Results There were 1 case of total resection,6 cases of subtotal resection invading cavernous sinus cases,diaphragma sellar was seen in 5 cases of resection of the tumor,and 2 cases showed no diaphragma sellar.The average operation time was 100 minutes.No intraoperative transfusion.Postoperative hemorrhage in 2 cases,and 1 death case in this group after 36 hours,and 1 case undergoing endoscopic hematoma resection and cured.Conclusions With the development of endoscopic techniques,indications for operation with the new changes,for the giant invasive pituitary tumor operation therapy,endoscopic technique provides a disposable operation resection,the method is safe and avoid catastrophic consequences.

It is imperative to establish a scientific and reasonable ranking and evaluation system for the comprehensive strength of medical departments in encouraging high-quality development of hospitals. The authors summarized the practice of Liaoning Cancer Hospital in establishing an evaluation index system of the comprehensive strength of medical departments according to relevant national standards, and in conducting quantitative evaluation from medical practice, education and research. The index system fell into the basic evaluation indexes and the on-site evaluation indexes. As required by individual functions and management requirements of the departments, medical departments were categorized into clinical departments, medical technology departments/supporting departments. As required by the latest regulations in China′s healthcare system reform and hospital strategic planning, the evaluation indexes were designed to be tuned dynamically, and the coefficient of progress was introduced for longitudinal evaluation. Thanks to the system in place in 2017, the hospitals have integrated multi-disciplinary resources, guided medical departments to improve quality and efficiency, hence launching overall progress in medical practice, education and research and sustainable development.

Traditional Chinese medicines have demonstrated clinical efficacy in preventing and treating chemotherapy-induced peripheral neuropathic pain(CIPNP).However,their specific clinical application and mechanism of action require further in-depth study and exploration.There is thus a need to develop more accurate and clinically relevant animal models that reflect the occurrence and development of human diseases as a tool for research.This review provides an in-depth analysis and discussion of the recent establishment and detection criteria of existing rat and mouse animal models of paclitaxel-induced peripheral neuropathic pain.We also evaluate and explain the application of these models for the prevention and treatment of CIPNP in traditional Chinese medicine,thus providing a theoretical basis and reference for future experimental and mechanistic research on the subject.This research will benefit clinical practice and promotion,offering valuable insights into preventing and treating CIPNP using traditional Chinese medicines.