Objective To investigate the radiotherapy curative effects on pains of bone metastases of breast cancer. Methods To analysis 32 patients retrospectively, in which 22 patients received radiotherapy(17 moderate pain, 5 severe pain, 6 dysfunction). Result 16 patients obtained complete remission with 6 cases partial response to radiation. Karnorfsky's score was improved and malfunction disappeared. Conclusion Radiotherapy is a simple and effective treatment on bone metastases of breast cancer with quick and persistent pain relieves.

Aortic stenosis is a common heart valve disease.Among adults,the most crucial cause of aortic stenosis is aortic valve calcification. Recent studies have shown that several factors may efficiently lead to aortic valve calcification such as age,valve structure,metabolism and genes.Although the main treatment for aortic valve calcification is still via surgery, with the further and deeper investigation in pathomechanism of aortic stenosis,we have made progress in pharmaceutical therapy for aortic valve stenosis patients.This article mainly focuses on the pathogenesis and treatment of calcified aortic valve stenosis.