1.Comparison of vildagliptin and acarbose monotherapy in patients with type 2 diabetes: a 24-week, multi-center, double-blind, double-dummy, active-controlled, randomized trial
Changyu PAN ; Qiuhe JI ; Wenying YANG ; Ping FENG ; Chao LIU ; Shengli YAN ; Yan GAO ; Jianping WENG ; Xin GAO ; Guang NING ; Zhimin LIU ; Haoming TIAN ; Weiping JIA ; Li YAN ; Yaoming XUE ; Yinzhang WANG ; Xiaohui GUO
Chinese Journal of Endocrinology and Metabolism 2009;25(4):386-390
inal event.
2.Clinical application of nateglinide:a Chinese expert consensus
Guang NING ; Lulu CHEN ; Mingdao CHEN ; Ping FEN ; Yan GAO ; Xiaohui GUO ; Yanbing LI ; Juming LU ; Changyu PAN ; Haoming TIAN ; Weiqing WANG ; Yaoming XUE ; Li YAN ; Longyi ZENG ; Dalong ZHU ; Dajin ZOU
Chinese Journal of Endocrinology and Metabolism 2011;27(5):后插1-后插3
Impaired eady phase insulin secretion is an important reason for leading to postprandial hyperglycemia.Nateglinide is a rapid-acting insulin secretagogue,which reduces postprandial blood glucose of type 2diabetic patient by restoring early phase insulin secretion.The efficacy and safety have been fully verified by clinical administration and it is more widely used to treat type 2 diabetic patients.Both sulfonylureas and glinides were named insulin secretagogue agents and regarded as alternative first-line drugs in the 2010 Chinese Guideline for treatment of type 2 diabetes.AACE/ACE Consensus statement claimed that glinides would be one of the important choices after metformin.In order to further guide the clinical application of nateglinide,16 national specialists in the field of endocrinology and metabolism of China discussed,drafted,and edited this consensus.The current consensus combined clinical evidences at home and abroad.systematically reviewed and summarized tlle results of these studies about nateglinide.It will provide guiding recommendations and reference concerning how to reasonably and effectively use nateglinide in the clinical practice.
3.Intervention caused changes in high risk sex behaviors among female sex workers from Vietnam in Yunnan, 2009-2013.
Haoming XUE ; Zhi LUO ; Zhibin ZHU ; Xi YANG ; Lihua YANG ; Jia YANG ; Lin DUO ; Email: DUOLIN@HOTMAIL.COM. ; Wenjun LIU
Chinese Journal of Epidemiology 2015;36(9):941-944
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OBJECTIVETo understand the prevalence of high risk sex behaviors and HIV infection status among the female sex workers (FSWs) from Vietnam in Yunnan province during a 5 year intervention project and provide evidence for the improvement of the behavior intervention among this population.
METHODSThe survey was conducted annually among Vietnamese FSWs sampled in a county near China-Vietnam border to collect the information about their demographic characteristics, high risk sex behaviors and HIV test results through questionnaire and in-depth interview by bilingual outreach team. The behavior intervention included peer advise, training, lectures, interactive games, free condom distribution. The database was set up with Excel 2003 and the results were analyzed with SPSS 16.0.
RESULTSThe condom use rates among the Vietnamese FSWs at commercial sex in last month were 1.5%, 36.0%, 67.7%, 86.5% and 90.3% (P<0.05) respectively; and the condom use rates at the latest sex were 89.5%,44.8%, 86.6%,92.5% and 99.0% respectively (P<0.05) . The HIV antibody positive rates were 7.5%, 3.6%, 5.9%, 4.0% and 3.1% respectively (P>0.05).
CONCLUSIONThe condom use rate of Vietnamese FSWs at commercial sex increased by more than 90% after the 5 year intervention project. However, the HIV-infection rate was still high. It is necessary to promote condom use among FSWs from Vietnam and their regular sex partners and strengthen the health education among clients.