1.Introduction of measurement methods of health utility for cancer patients
Bo LIU ; Juan XU ; Kemmler GEORG ; Haofei LI ; Enxue CHANG ; Wanji ZHENG ; Wen GU ; Lan ZHOU ; Rui LIU ; Weidong HUANG ; Nan LUO
China Pharmacy 2023;34(4):450-456
Cancer is one of the major fatal diseases that seriously threaten human health, and its burden needs to be solved urgently. Health technology assessment (HTA) can provide scientific evidence-based basis for cancer diagnosis, treatment, prevention and related policy formulation. Cost-utility analysis is the gold standard for economic evaluation in HTA, and the accurate measurement of its health utility is one of the key elements to determine the accuracy of its results. This article focuses on systematic introduction of direct measures, multi-attribute health utility scales, and mapping methods in the field of cancer measurement and reviews their applications in cancer patients. Among them, direct measures are complex, costly, and require a high level of subject knowledge; multi-attribute health utility measures are currently the preferred method for measuring health utility in cancer patients; with the continuous development and refinement of disease-specific utility measures in multi-attribute health utility instruments, the mapping method may gradually decrease in future applications. This paper can provide a reference for the selection of health utility measurement tools for HTA in the field of cancer, and provide evidence-based basis for optimizing resource allocation and policy formulation in the field of cancer.
2.Is oral microbiome of children able to maintain resistance and functional stability in response to short-term interference of ingesta?
Fangqiao WEI ; Xiangyu SUN ; Yufeng GAO ; Haoyu DOU ; Yang LIU ; Lili SU ; Haofei LUO ; Ce ZHU ; Qian ZHANG ; Peiyuan TONG ; Wen REN ; Zhe XUN ; Ruochun GUO ; Yuanlin GUAN ; Shenghui LI ; Yijun QI ; Junjie QIN ; Feng CHEN ; Shuguo ZHENG
Protein & Cell 2021;12(6):502-510