Objective To investigated the efficacy of minimally invasive technique combined with anterolateral thigh flap in repairing skin and soft tissue defects of leg and foot.Methods Anterior thigh flap was used to repair 20 cases of skin and soft tissue defects of leg and foot,the lesions defect area was 3.9 cm × 7.4cm-11.4 cm × 20.6 cm.Given the appropriate minimally invasive techniquesurgical treatment,the effect of follow-up was observed after operation.Results The supply valve area healed.The postoperative flaps of 20cases of patients all survived,no vascular crisis occurred.The color of skin flap was normal,close to normal skin color,and the elasticity of the skin was good,no crack,no fat,no pigmentation and other complications occurred,and no effect on shoes and ankle joint activities.Excellent and good rate of overall assessment flap was 90％(excellent in 12 cases,good in 6 cases);excellent and good rate of Mazur ankle function evaluation was 95％(excellent in 12 cases,good in 7 cases).Conclusion The minimally invasive technique combined with anterolateral thigh flap is a more ideal method to repair the leg and foot soft tissue defects.

Objective To discuss the clinical manifestation and diagnosis of lymphomatous infiltration of the lung.Methods Clinical informations of 17 cases of lymphomatous infiltration of the lung were assessed.Results of 78 patients with malignant lymphoma,17 patients were infiltrated in lung.3 cases were Hodgkin's disease,14 cases were non -Hodgkin's lymphoma.All cases were advanced patients.Survival time of 1 patient was more than 5 years.Survival time of 1 patient which was the shortest was 2 months.Conclusion Patients with lymphomatous infiltration of the lung are not rare.The clinical symptoms and signs are not typical,image diagnosis is the main part in diagnosis of lymphomatous infil- tration of the lung.

Objective:To observe the influence of ischemia/reperfusion(simulated by anoxia) on the characteristics of K~(+) channels in renal tubular epithelial cells.Methods: Healthy renal tubule epithelial cells were divided into normal control group(cultured in serum-free RPMI 1640 medium),anoxic group(treated with antimycin A + serum-free RPMI 1640 medium),and oxidative stress group(H_(2)O_(2)+ serum-free RPMI 1640 medium)(n=15).The whole-cell patch clamp technique was used to examine the characteristics of K~(+) channels in renal tubular epithelial cells.Results: The transmembrane K~(+) current in tubular epithelial cells was voltage-dependent and could be blocked by K~(+) channel blocker Ba~(2+).The transmembrane potential levels in anoxic group and oxidative stress group were remarkably higher than that in normal control group(P

As the most popular simplified model of the optical imaging system, the acquisition of the Gaussian point spread function (PSF) parameter is one of the hotspots and key points on which people do research in the field of image restoration. Based on the idea by which there exists deterministic mathematical relationship between Gaussian OTF feature points as well as its parameter and the frequency representation of the image in an existed literature, we proposed an automatic, accurate, stable, and improved approach. This method is able to give prominence to the related calculation feature by a Gaussian convolution and degeneration operation and finally realize the automatic esti mation of PSF parameter of a microscopic image. Experiments have proved that a good restoration result can be achieved utilizing the estimated PSF by the present method, which is of considerable application and reference value in restoration of other sorts with Gaussian approximate PSF model or 3D microscopic image restoration.
Algorithms ; Humans ; Image Interpretation, Computer-Assisted ; Imaging, Three-Dimensional ; Microscopy ; Models, Theoretical ; Normal Distribution

Stromal cell-derived factor-1(SDF-1)is an early cell growth factor which belongs to a subfamily of chemokines.The CXCR4 is SDF-1 receptor.The SDF-1 interacting with CXCR4 plays important roles in physiological and pathological processes such as hematopiesis, stem cell homing,angiogenesis and leukemic cells infiltrating.To study the expression of CXCR4 in leukemia and the relationship between CXCR4 and leukemic cells infiltration can add indicators for leukemic MIC diagnosis of immunology indexes and have great significance to take molecule targeted therapy for preventing leukemia from infiltration or relapse as well.

0.05)and the treatment costs were 1 104.60 yuan,2 049.24 yuan and 3 247.99 yuan,respectively(P

Image interpolation is often required during medical image processing and analysis. Although interpolation method based on Gaussian radial basis function (GRBF) has high precision, the long calculation time still limits its application in field of image interpolation. To overcome this problem, a method of two-dimensional and three-dimensional medical image GRBF interpolation based on computing unified device architecture (CUDA) is proposed in this paper. According to single instruction multiple threads (SIMT) executive model of CUDA, various optimizing measures such as coalesced access and shared memory are adopted in this study. To eliminate the edge distortion of image interpolation, natural suture algorithm is utilized in overlapping regions while adopting data space strategy of separating 2D images into blocks or dividing 3D images into sub-volumes. Keeping a high interpolation precision, the 2D and 3D medical image GRBF interpolation achieved great acceleration in each basic computing step. The experiments showed that the operative efficiency of image GRBF interpolation based on CUDA platform was obviously improved compared with CPU calculation. The present method is of a considerable reference value in the application field of image interpolation.
Algorithms ; Image Processing, Computer-Assisted ; Imaging, Three-Dimensional ; Normal Distribution ; Software

BACKGROUND:Studies have shown that the physical development potential is often associates with certain combinations of hand print features.
OBJECTIVE:To analyze the body shape and structure characteristics of national women’s handbal team athletes.
METHODS:Fifty national women’s handbal team athletes were col ected from Shanghai, Beijing, Tianjin and Anhui provinces and PLA. The body shapes of the athletes were measured by the Research Institute of National Sports Council, and the hand prints were col ected. The common factors of body shape and structure characteristics were analyzed with factor analysis method, including height, weight, forearm length, wrist circumference, hand length, hand width and index finger length and large-handedness index.
RESULTS AND CONCLUSION:The body shape and structure characteristics of national women’s handbal team athletes could be divided into four types:long trunk lean type indicator, hand skeleton and muscle fiber development level index, flexible quality indicators as wel as the alertness and mental level indicators. The long trunk lean type indicator was the main factor to affect body shape and structure characteristics of national women’s handbal team athletes.

Since functional visual acuity(FVA) was put foward,it is regraded as a kind of functional vision examination which can well reflect an individual' s performance in relation to certain daily activities involving visual tasks,the concept and the measurement is updating with the progress of technology.This examination was first applied in the patients with dry eye,and now it's applicable to detect and evaluate the refractive error,cataract,retinal pathological changes,or the eyedrops' use,and it can provide evidences for the early dignosis or the effects of thraphy of some ocular disease.In this paper,an introduction of the concept,methods and system of FVA,the clinical application of FVA in dry eye,refractive error,cataract,and in patients with fundus diseases and the research progress were reviewed.

Objective:To discuss the effect of bone marrow on chemotaxis of aggregation of macrophages in venous thrombosis.Methods:SD adult rats were divided randomly into normal group,sham operation group,thrombus group and rhG-CSF group.Peripheral blood was harvested at 30min before operation and on the 7th and 14th day after operation.Level of MCP-3 in peripheral blood was detected with ELISA.Inferior vena cava specimens of thromus group and rhG-CSF group were collected at postoperative 7th and 14th day.With the application of RT-PCR,expression of MCP-3mRNA in thrombus was detected.Results:The level of MCP-3 in peripheral blood of rhG-CSF group was significantly higher than that before operation and also higher than the levels of MCP-3 in peripheral blood of sham operation group and thrombus group on the 14th day after operation,(P