Meningocerebral haemorrhage due to the rupture of malformation of cerebral arterio venous fistula is neurosurgical emegency that requires the radical management to prevent from relapsed haemorrhage. Currently in Vietnam, the operation for malformation removal is an unique technique. The restrespective study on 16 cases suffered the rupture of malformation of cerebral arterio venous fistula in Vietduc during 1999-2000 showed the encourage results. 81.3% of malformations were radically removed, 18.7% of malformation were partial removed and experienced ligation of artery the outcomes: good (81%) and no death
abnormalities ; Arteries ; surgery

A retrospective study on 14 case of ruptured cerebral cranial carotid aneurysm operated in Viet Duc Hospital during 1998 - 2000 has shown that the clinical outcome and method of operation found well in 78.6% of patients. The time for operation was usually late (often 2-3 weeks of bleeding).
Aneurysm, Ruptured ; Cerebral Arterial Diseases

3 cases of intracranial aneurismal residue following clipping at Viet Duc Hospital were studied. The causes of this condition were anatomical and technical. It is necessary to identified prior surgery the cause of hemorrhage, to limit the disruption of aneurism, to expose entirely the neck of aneurism before the setting of clip and to explore throughly the place of clip- Anterigraphy or systematic Xray control should be made for checking the results
Intracranial Aneurysm ; etiology ; Aneurysm ; Intracranial Arterial Diseases

This association had been reported for long time with a frequency of 2.7-23% of cases of intracerebral arteriovenous connection. This association increases the risk of cerebral meningo hemorrhage. 3 cases of cerebral meningo hemorrhage associated with intracerebral arteriovenous connective malformation were studied retrospectively and treated at Viet Duc Hospital from January 1999 to January 2004. The presence of aneurysm in cerebral arteriovenous connection was an important predictive factor for the hemorrhage possibility, leading to cerebral hemorrhage
Aneurysm ; Arteriovenous Malformations ; Intracranial Arteriovenous Malformations ; abnormalities

Jaundice (abnormal elevation of bilirubin) is common in clinical practice.At present bilirubin is detected by measuring total bilirubin (TB) and direct bilirubin (DB) in hospital.Indirect bilirubin (IB) is the difference of TB and DB.Direct bilirubin reflects mainly the conjugated bilirubin but they are not all equivalent.Indirect bilirubin and unconjugated bilirubin are the same condition.In clinical practice,the proportion of DB (or IB) in TB is more significant than their level of elevation.The cause of jaundice could be roughly determined by analyzing the proportion of DB (or IB) in TB.The methodology and quality of bilirubin detection are quite different in hospitals in our country.The proportion of DB aud IB in TB in detection of bilirubin is also quite different in hospitals.It leads to a big puzzle to the diagnosis and differential diagnosis of jaundice for clinical doctors.It is suggested that the quality control of bilirubin detection should be strengthened in laboratory in hospital.On the bases of strict quality control of bilirubin detection,proper adjustment of the proportion of DB and IB as to make it consistiug with clinical practice and pathogenesis of diseases,and making the proportion stable for long time are also suggested.

Pancreatic cancer normally is lethal and difficult to treat.Recently,although chemotherapy drugs such as gemcitabine for the treatment achieved a certain effect, but the survival rate has not improved significantly. Over the past decade, a large number of studies that aimed to implicated in pancreatic tumor gemcitabine metabolism and resistance mechanisms. Recent data show that it is a great value for predicting efficacy in the treatment of pancreatic cancer with gemcitabine by detecting pancreatic cancer -related molecules and genes, especially in the field of individual therapy. This review describes advances in the studies of related molecules and genes affecting the efficacy of gemcitabine for pancreatic cancer.

Objective To investigate the clinical application value of laparoscopic minimally invasive surgery in the treatment of gynecologic disease.Methods The clinical data of 415 patients with laparoscopic surgery(laparoscopic group) and 187 patients with laparotomy at the same period (laparotomy group) because of gynecologic disease were analyzed,and the operative time,blood loss,postoperative passage of flatus,postoperative pain,postoperative complication rate,hospital days and average cost of hospitalization were compared.Results The operative time,blood loss,postoperative passage of flatus,postoperative pain,hospital days and average cost of hospitalization and postoperative complication rate of laparoscopic group was (35.1 ± 8.8) min,(56.8 ± 4.3) ml,(25.0 ± 6.0) h,(4.0 ± 3.0) d,(3 894.7 ± 1 028.5) yuan,1.9％,respectively,and shorter than those of laparotomy group [(50.2 ± 12.3) min,(83.5 ±23.7)ml,(58.0±30.0)h,(14.0±8.0)d,(6 628.1 ±1 834.9)yuan,8.2％] (t =2.366,2.154,6.903,10.501,7.674,3.095,all P ＜ 0.05);The postoperative passage of flatus had no significant difference between the two groups (t =0.843,P ＞ 0.05).Conclusion Laparoscopic minimally invasive surgery can be safely and effectively utilized in gynecologic diseases for its little injury,shorter operative time,less bleeding,less pain,less complications and quicker recovery and so on,and it should be worth of clinical promotion.

Automation of diagnostic labs are being developed at full speed in China,but some unreasonable large scale and comprehensive import are preferred.Consequently lots of valuable equipments have not been fully used and great recourses have been wasted.So the hospital and diagnostic lab policy makers should ask themselves about the equipment scale to match the requirement.

Recombinant human growth hormone (rhGH) has been widely used in clinical treatment of growth hormone deficiency(GHD),and has achieved satisfactory effect.Growth hormone (GH) can stimulate liver cells to produce insulin-like growth actor(IGF-1) which mediated GH growth promoting effect.The majority of IGF-1 combine with insulin like growth factor binding protein 3.IGF-I promotes cell mitotic and inhibit cell apoptosis,in recent years,some scholars have reported that there is a certain relationship between IGF-1 and tumor occurrence and development,and thus leading to the attention to the efficacy and safety of rhGH treatment.

Neuroblastoma is one of the solid tumors in children which easily metastasizes to bone.It causes radiographic appearance of osteoclastic reactions after bone metastases.In the process,neuroblastoma cells,osteoblasts and bone stromal cells secrete a series of related factors to promote bone metastases.In this paper,the progress of the mechanism in bone destruction caused by neuroblastoma is reviewed.