3 cases of intracranial aneurismal residue following clipping at Viet Duc Hospital were studied. The causes of this condition were anatomical and technical. It is necessary to identified prior surgery the cause of hemorrhage, to limit the disruption of aneurism, to expose entirely the neck of aneurism before the setting of clip and to explore throughly the place of clip- Anterigraphy or systematic Xray control should be made for checking the results
Intracranial Aneurysm ; etiology ; Aneurysm ; Intracranial Arterial Diseases

This association had been reported for long time with a frequency of 2.7-23% of cases of intracerebral arteriovenous connection. This association increases the risk of cerebral meningo hemorrhage. 3 cases of cerebral meningo hemorrhage associated with intracerebral arteriovenous connective malformation were studied retrospectively and treated at Viet Duc Hospital from January 1999 to January 2004. The presence of aneurysm in cerebral arteriovenous connection was an important predictive factor for the hemorrhage possibility, leading to cerebral hemorrhage
Aneurysm ; Arteriovenous Malformations ; Intracranial Arteriovenous Malformations ; abnormalities

Meningocerebral haemorrhage due to the rupture of malformation of cerebral arterio venous fistula is neurosurgical emegency that requires the radical management to prevent from relapsed haemorrhage. Currently in Vietnam, the operation for malformation removal is an unique technique. The restrespective study on 16 cases suffered the rupture of malformation of cerebral arterio venous fistula in Vietduc during 1999-2000 showed the encourage results. 81.3% of malformations were radically removed, 18.7% of malformation were partial removed and experienced ligation of artery the outcomes: good (81%) and no death
abnormalities ; Arteries ; surgery

A retrospective study on 14 case of ruptured cerebral cranial carotid aneurysm operated in Viet Duc Hospital during 1998 - 2000 has shown that the clinical outcome and method of operation found well in 78.6% of patients. The time for operation was usually late (often 2-3 weeks of bleeding).
Aneurysm, Ruptured ; Cerebral Arterial Diseases

Based on the traditional fear extinction training paradigm, the retrieval-extinction para-digm rewrites fear memory within the reconsolidation window,and reduces their fear response by decreasing the valence of fear stimulus. From the perspective of psychology,the main reason of addicts relapse is that the intensive memory of the painful experience inspired when protracted withdrawal symptoms of drug depend-ence. The reduction of the sensitivity of drug related memory, which is the key of drug detoxification is to change the memory caused by drug related cues. The retrieval-extinction paradigm provides no drug treatment and a new non-invasive model for addicts,and a new perspective to reduce the relapse rate,and to improve the quality of life of addicts. We can do empirical research which using memory retrieval-estinction paradigm on drug addicts in the future.The memory retrieval paradigm can be applied to empirical research in drug ad-dicts in future.

Absent in melanoma 2(AIM2),as a cytoplasmic DNA sensor,can perceive the cytoplasmic dsDNA which released by the cells infected with DNA virus or bacteria.AIM2 will be raised by Apoptosis-associated speck-like protein containing a CARD to produce inflammation complex,activate of Caspase-1,promote the maturation,and secretion of IL-1β and IL-18,or lead to pyroptosis.AIM2 plays an importation role in initiating immunity.Recent research shows that AIM2 has an influence on the occurrence and progress in tumor,it acts as a tumor suppressor and inhibits tumor progression in liver and breast carcinoma;However,AIM2 shows the carcinogenic effect of promoting tumor development on cervical carcinoma and oral squamous cell carcinoma.These results contribute to the diagnosis and prognosis of malignant tumor.

The distribution of factor H of serum phenotypes were studied using the ultra-thinpolyacrylamide gel isoelectric focusing (PAGIEF) followed by Immunoblotting technique in 203Chinese Han population in Liaoning area. The gene frequencies were as follows: HFA0. 4828,HFB0.5172. The observed numbers of the phenotype were in agreement with the expected numbers underthe Hardy-Weinberg equilibrium. The gene frequencies among Chinese and other population werecompared.

The paper argues that if the policy of separating pharmacy from medicine is to be implemented in China in the current situation, medical institutions will appear to be the direct interest losers while the broad masses of drug consumers (or payers) will be the eventual interest losers. In other words, consumers (or payers) will have to cover the costs entailed in separating pharmacy from medicine whereas the channels for drug circulation(wholesalers and retailers) and the drug producers will benefit from the policy. The government will be faced not only with the pressure of either raising the level of charges for medical services or increasing compensations for medical institutions, but also the dilemma of whether to stunt the development of medical institutions or to allow the abnormal growth of medical expenses. Besides, it will be confronted with moral accusations of supporting the channels for drug circulation at the expense of the interests of medical institutions and consumers and increased government input. These problems have already emerged in an embryonic form in the cunent implementation of the policy of "progressive separation of pharmacy and medicine" by the drug administration agencies. The ideal state for adopting the policy of separating pharmacy from medicine would be the overall reduction of drug prices by 26% to 30%, the turnover of the drug gross profit valued at 46.9 to 54.7 billion yuan into the scope for readjusting the level of charges for medical services, and a yearly readjustment in future of the level of charges for medical services according to the price index.

Objective To investigate effect of Danhong injection combined with atorvastatin treatment of patients with unstable anginapectoris.Methods Ninety patients with unstable anginapectoris from Mar.2010to Dec.2013 in the First People's Hospital were selected and randomly grouped as control group(n=40) and atorvastatin-Danhong injection group(n =50).All patients in two groups were treated with routine therapy,and patients in the atorvastatin-Danhong injection group were also treated with atorvastatin at dose of 20 mg per day for 15 days and Danhong injection at dose of 30 ml in 250 ml physiological saline per day for 15 days.The level of high-sensitivity C-reactive protdn(hs-CRP) in serum and the haemodynamics of two groups during before and post-treatment were measured and analyzed.Results The effective rate of atorvastatin-Danhong injection group was 84.0％ (42/50),higher than that in control group (70.0％ (28/40),x2 =5.738,P =0.039).The level of hs-CRP in two groups at after treatment were (7.6±2.1) and (3.6±1.7) mg/L,lower than those at pretreatment((1 8.6±4.7) mg/L,(19.2±4.2) mg/L),and the differences were significant (t =8.644,7.848;P =0.004,0.007).Compared with control group after treatment,the level of hs-CRP in atorvastatin-Danhong injection group decreased rapidly (t =6.384,P =0.009).Compared with pre-treatment,the low cut blood viscosity(LCBV),high shearrate blood viscosity(HSBV),plasma viscosity and red cell assembling index in two groups were decreased remarkably(P＜0.05).Compared with control group at post-treatment,the LCBV,HSBV,plasma viscosity and red cell assembling index in atorvastatin-Danhong injection group were significantly declined (t=5.142,4.672,5.738,5.354;P＜0.05).Conclusion Danhong injection combine with atorvastatin improves the haemodynamics in patients with unstable anginapectoris and induce the inflammatory reaction,and it has the better the effects.

Objective To investigate the level of plasma malondialdehyde (MDA)and coenzyme Q10 (CoQ10)in patients with type 2 diabetes mellitus,diabetic leg ulcer(DLU).Methods The DLU group consisted of 15 patients with leg ulcers and type 2 diabetes mellitus (7 men and 8 women).The diabetes group consisted of 15 patients with type 2 diabetes mellitus (8 men and 7 women).Ten healthy individuals,age and sex matched with the patients,were used as a control group.Laboratory investigations in the form of glycosylated hemoglobin,plasma MDA and plasma CoQ10 were assessed for all patients and controls.Results The study revealed that in the diabetes group,especially in the DLU group,the MDA level [(7.07 ±3.15)μmol/L and (3.15 ±2.66)μmol/L]was signifi-cantly higher than control group [(4.28 ±0.41)μmol/L]and the index difference between them (F =104.675,P <0.01),while CoQ10 levels in the two groups data[(0.33 ±0.16)mg and (0.16 ±0.16)mg ]were significantly lower than the control group [(0.86 ±0.13)mg](F =46.709,P <0.05).Conclusion Type 2 diabetic patients, especially with DLU,are at increased risk of oxidative stress manifested by increased plasma MDA.