Objective To retrieve and integrate relevant evidence on best sleep position nursing in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) so as to provide scientific and effective references for clinical departments.Methods Firstly, we put forward questions aiming at sleep position of OSAHS patients with the Johns Hopkins nursing evidence-based practice model. And then, we retrieved related studies by computers in the round and carried out assessment of literature quality and level of evidence for various researches. Finally, we integrated the evidence and made recommendations.Results Combining the judgment of specialized persons, a total of 7 evidences on sleep position nursing of OSAHS patients were integrated, such as adapt-to-the-crowd and effects of position nursing, the best sleep position and method to maintain position.Conclusions The sleep position nursing is very important for OSAHS patients. In further clinical transformation and application, clinical departments should well judge on selection of patients, conditions of evidence application to make sensible decisions so as to improve the quality of nursing by improving patients' sleep hypopnea with the scientific nursing methods through applying the best evidence.