1. Polymodal Functionality of C. elegans OLL Neurons in Mechanosensation and Thermosensation
Yuedan FAN ; Wenjuan ZOU ; Jia LIU ; Umar AL-SHEIKH ; Hankui CHENG ; Duo DUAN ; Duo DU CHEN ; Siyan LIU ; Lijun KANG ; Yuedan FAN ; Wenjuan ZOU ; Jia LIU ; Umar AL-SHEIKH ; Hankui CHENG ; Duo DUAN ; Duo DU CHEN ; Siyan LIU ; Lijun KANG ; Luyi CHEN ; Jilei XU ; Firdosh RUHOMUTALLY
Neuroscience Bulletin 2021;37(5):611-622
Sensory modalities are important for survival but the molecular mechanisms remain challenging due to the polymodal functionality of sensory neurons. Here, we report the C. elegans outer labial lateral (OLL) sensilla sensory neurons respond to touch and cold. Mechanosensation of OLL neurons resulted in cell-autonomous mechanically-evoked Ca