The statistics of purified protein derivative (PPD) test and chest radiograph of freshmen at a university from 2007 to 2010 were collected and examined.The result showed 25 tuberculosis cases (a prevalence rate of 0.18％) and 1 790 cases (13.40％) with strong positive PPD.After giving informed consents,the students with strong positive result and no abnormality on chest radiograph were divided into two groups.The treatment group (n =814) received precautionary anti-tuberculosis treatment while the nontreatment group (n =976) had no treatment.And 34 tuberculosis cases were found during four years in school (0.25％).Except for freshmen in 2008,the prevalence rate of the strong positive PPD groups much higher than that of the positive and negative groups and the difference had statistic significance between the groups (x2 =23.20,10.58,18.80,P ＜ 0.05).Therefore PPD test and chest radiograph are two main methods for an early diagnosis of tuberculosis among freshmen.Adopting precautionary anti-tuberculosis treatment for students with strong positive PPD and regular physical examinations are effective measures for tuberculosis control at universities.

Objective To evaluate the feasibility of optic nerve subarachnoid space in non?invasive qualitatively diagnosis of intracranial hypertension. Methods In this retrospective study, patients who received lumbar puncture from October 2009 to June 2015 were enrolled and divided into normal intracranial pressure group (41 cases) and intracranial hypertension group (39 cases). Optic nerve subarachnoid space width (SASW) behind ocular 3 mm (SASW?3),9 mm (SASW?9),and 15 mm (SASW?15) were measured on MRI and compared between groups. Chi?square test, t test and ROC analyses were used. Results SASW?3,SASW?9,and SASW?15 were (1.16±0.21), (0.98±0.21) and (0.92±0.17) mm in normal group and (1.46 ± 0.20), (1.29 ± 0.19) and (1.17 ± 0.20) mm in intracranial hypertension group, respectively. According to independent samples t test,SASW?3,SASW?9,and SASW?15 of intracranial hypertension group was significant larger than those at the same measured site of normal group (P<0.01). According to MedCalc analysis,Receive operating characteristic (ROC) area was 0.849 in SASW?3 and when the cut?off value was fixes as 1.19 mm,the sensibility and specificity were 94.9% and 63.4%,respectively. ROC area was 0.849 in SASW?9 and when the cut?off value was fixes as 1.10 mm, the sensibility and specificity were 84.6% and 78.0%,respectively. ROC area was 0.824 in SASW?15 and when the cut?off value was fixes as 1.06 mm,the sensibility and specificity were 69.2% and 80.5%,respectively. Conclusion SASW?9 can be used to screen and monitor the intracranial hypertension as a non?invasive tool.