Objective To evaluate the efficacy of transcatheter arterial chetnoembolization (TACE) in adjuvant with ther - motherapy in the treatment of primary hepatic carcinomas (PHCs) ,and to obsorre the changes of T - lymphocyte subsets and naturalkiller(NK) cells before and after therapy and the clinical significance. Methods Forty patients with advanced PHCs were randomly divided into two groups (the study group and the control group) ,with 20 cases in each. The patients in the study group were treated by TACE in adjuvant with thermotherapy, and the patients in the control group were treated by TACE alone. The changes of T - lymphocyte subsets and NK cells were examined by im - munofluorescence staining in 40 cases of PHC before and after TACE in adjuvant with ther - motherapy and were compared with those of 20 cases who received conventional interventional chemotherapy (control group). Results The short -term remission rate of the study group and control group were 65% and 40% , respectively (P