2.Determination of total Bromine in urine by inductively coupled plasma mass spectrometry (ICP-MS).
Changmei ZHOU ; Hangju ZHU ; Deye LIU ; Rongming MIAO ; Lihong YING ; Baoli ZHU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2015;33(5):396-397
OBJECTIVETo establish a method to determine total bromine in urine.
METHODDiluted urine samples were directly introduced into ICP-MS then quantized by standard curve.
RESULTTotal bromine in urine was linear within 1.0~50 mg/L with r > 0.999, When spiked at a concentration of 0.020 mg/L, 0.050 mg/L, 0.150 mg/L, the recovery was 95%~98%, intra-assay precision was 1.4% 3.2%, inter-assay precision was 3.4% to 5.0%. Urine could store in -20 °C refrigerator 3 months without any bromine loss.
CONCLUSIONUsing ICP-MS to determine the urinary total bromine, the method is fast, accurate, wide linear range of features, could meet with the requirement of Part 5 of occupational health standards guide: Method determination of chemical substances in biological materials (GBZ/T 210.5-2008), a strong competitive advantage in a wide range of survey, suitable for promotion.
Bromine ; urine ; Humans ; Mass Spectrometry
Result Analysis
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