1.Cytomegalovirus infection in patients with HIV infection.
Ji Yong MOON ; Sung Hee HAN ; Hang Lak LEE ; Oh Young LEE ; Ho Soon CHOI
Korean Journal of Medicine 2005;68(1):121-122
No abstract available.
Cytomegalovirus Infections*
;
Cytomegalovirus*
;
HIV Infections*
;
HIV*
;
Humans
2.A case of fetal atrial flutter with hydrops fetalis.
Seong Hang CHOI ; Kee Hyoung LEE ; Chang Sung SOHN ; Ju Won LEE ; Young Chang TOCKGO
Journal of the Korean Pediatric Society 1993;36(8):1165-1170
Fetal hydrops is often serious and associated with a high perinatal motality rate. Cardiac causes of fetal hydrops include congenital heart diseases and rhythm disturbances. An irregular fetal heart rate may indicate atrial fibrillation and atrial flutter with variable AV conduction. Fetal atrial flutter is characterized by the pressence of flutter waves which are regular sawtooth undulations in the baseline that are larger than p waves. Authors experienced a case of fetal atrial flutter with hydrops fetalis at 30 week's gestation which was confirmed by fetal M-mode echocardiogram and electrocardiography. A new born infant had shown to have atrial flutter in utero and after delivery was successfully converted to normal sinus rhythm with digoxin and quinidene.
Atrial Fibrillation
;
Atrial Flutter*
;
Digoxin
;
Edema*
;
Electrocardiography
;
Female
;
Heart Diseases
;
Heart Rate, Fetal
;
Humans
;
Hydrops Fetalis*
;
Infant
;
Pregnancy
3.Bone infection associated with pressure sores: a clinical study.
Hang Seok CHOI ; Gyeol YOO ; Jong Won RHIE ; Sung Shin WEE ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(4):679-685
Pressure sores are common complications in patients with spinal injuries or cerebrovascular accidents. The management of pressure sores requires prolonged hospitalization and repeated surgical interventions with a high recurrence rate. Particularly osteomyelitis following initial pressure sores persistently complicates wound healing and recovery. Furthermore, it may also ultimately result in serious sepsis; thus an early diagnosis of osteomyelitis in pressure sore patients is crucial along with appropriate surgical and antibiotic therapy. Although many diagnostic methods were reported, there is no single 'gold' standard for early diagnosis of pressure sore-associated osteomyelitis. Authors reviewed pre-operative CBC, plain X-ray, Tc-99m bone scan, and post-operative biopsy results in 37 patients who had received surgical treatment for pressure sores in a 5-year period from September 1991 to August 1996. Based on these reviews, authors compared and analyzed the sensitivity and specificity in diagnosing osteomyelitis.The results were as follows: 1. Of 37 patients studied, 25 cases were confirmed histologically as osteomyelitis. Ischial region revealed the highest incidence of pressure sore-related osteomyelitis(78%, 14 out of 18 cases) while the regional incidence was as following in descending order : ischial, sacral, and greater trochanteric area. 2. Tc-99m bone scan had superior sensitivity(100%) and specificity(83%) to other pre-operative studies in diagnosing osteomyelitis.In conclusion, authors suggest that Tc-99m bone scan is the best diagnostic method because of its high sensitivity and specificity if osteomyelitis is clinically suspected in pressure sore patients. And in case the test result is positive, agressive surgical bone resection and appropriate antibiotic therapy based on bacterial culture from deep bone specimen should be combined to prevent complications or recurrences.
Biopsy
;
Early Diagnosis
;
Femur
;
Hospitalization
;
Humans
;
Incidence
;
Osteomyelitis
;
Pressure Ulcer*
;
Recurrence
;
Sensitivity and Specificity
;
Sepsis
;
Spinal Injuries
;
Stroke
;
Wound Healing
4.The study of serum lipids in grossly obese elementary school students in Seoul.
Seong Hang CHOI ; Kyoung Bum KIM ; Se Geun PARK ; Ji Tae CHUNG ; Chang Sung SON ; Young Chang TOCKGO
Journal of the Korean Pediatric Society 1993;36(1):73-80
Our study surveded 418 obese first grade elementary school children(279 male and 139 female), in seoul, and measured levels of serum total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride were measured in addition to the measurement of body weight and height. The following results were obtained. 1) Obesity index was catergorized into mild, moderate, and severe, and the percentage of mild was 6.8%, moderate 48%, severe 45.7% respectively in surveyed children. 2) The average level of total cholesterol was 1.66.60 27.63mg/dl, HDL cholesterol 50.22+/-0.68mg/dl, LDL cholesterol 82.23+/-1.26mg/dl. 3) Atherogenic index was calculated, and obtained value was 2.45+/-0.48. It showed higher statstical significance in boys than in girls(p<0.05). 4) There was no significant difference in average level of total cholesterol, LDL cholesterol, and triglyceride in accordance of the severity of obesity. 5) Statistical significance was found in different average ievels of HDL cholesterol and atherogenic index according to obesity index (p<0.05). 6) There was a statistical significance in the average values of Kaup index and Rohrer index in accordance with obesity index (p<0.000). 7) There was no correlation between abnormal levels of total cholesterol, HDL cholesterol, and LDL cholesterol and the severity of obesity. 8) Abnormal levels of triglyceride, atherogenic index, Rohrer index and Kaup index had a statistical significance since their levels. 9) There was a correlation between atherogenic index and body measurement. Total cholesterol level showed correlation with obesity index, and HDL cholesterol with Kaup index and arm circum ference.
Arm
;
Body Weight
;
Child
;
Cholesterol
;
Cholesterol, HDL
;
Cholesterol, LDL
;
Humans
;
Male
;
Obesity
;
Seoul*
;
Triglycerides
5.A Case of Pulmonary Blastoma.
Kang Soo PARK ; Hee Yong HAM ; Sung Bo HWANG ; Soo Cheon CHOI ; Shin Young LEE ; Il Hang KOH
Tuberculosis and Respiratory Diseases 1994;41(4):418-423
Pulmonary blastoma is a rare lung tumor resembling fetal lung tissue. Pathologically the tumor can be classified to 2 groups, well-differentiated fetal adenocarcinoma(WDFA) and biphasic blastoma. WDFA has more favorable prognosis with fewer metastasis at initial presentation and fewer recurrence after treatment. We experienced a case of pulmonary blastoma in 32-year-old female patient. The patient was referred to our hospital because of abnormal mass shadow in right middle lobe. The diagnosis of pulmonary blastoma(WDFA type, Stage I T2NOMO) was confirmed after right middle lobectomy. We followed up 22 months without an evidence of recurrence.
Adult
;
Diagnosis
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Female
;
Humans
;
Lung
;
Neoplasm Metastasis
;
Prognosis
;
Pulmonary Blastoma*
;
Recurrence
6.Patterns of Nerve Conduction Blockade by Different Combinations of Lidocaine-bupivacaine Mixture.
Sung Kang CHO ; Joon Woo LEEM ; Hang Soo LEEM ; Sung Min HAN ; Hyun Seok KONG ; Yoon CHOI
Korean Journal of Anesthesiology 2000;38(4):708-712
BACKGROUND: A mixture of local anesthetics such as lidocaine and bupivacaine has frequently been used in clinical practice. The rationale behind this is to take advantage of lidocaine's rapid onset and bupivacaine's perpetuation in anesthesia. The purpose of this study was to examine the changes in the onset and recovery of nerve blocking action exerted by the different combinations of these two in the mixture. METHODS: Isolated sciatic nerve preparations obtained from adult male Sprague-Dawley rats were used in this study. Recordings of A-fiber compound action potentials (A-CAPs) were made at the end of the isolated nerve while single pulse stimuli (0.5 msec, supramaximal intensity, 2 Hz) were applied to the opposite end of the nerve. Seven different composition of lidocaine-bupivacaine mixtures were prepared (0 : 6, 1 : 5, 2 : 4, 3 : 3, 4 : 2, 5 : 1, 6 : 0 vol./vol.), where basal concentrations of lidocaine and bupivacaine were 0.2% and 0.05%, respectively. Amplitudes of A-CAPs were measured before, during and after perfusion of mixture solution. The time needed for A-CAPs amplitude to decrease to 10% of the basal value after starting perfusion (onset time) and that needed to reach to 50% of the basal value after ceasing the perfusion (recovery time) were measured. RESULTS: With increasing concentration ratios of lidocaine to bupivacaine in the mixture as mentioned above, the following onset and recovery times were obtained (6.0 +/- 0.3, 5.6 +/- 0.3, 6.0 +/- 0.5, 8.3 +/- 0.5, 7.3 +/- 0.6, 7.8 +/- 0.3, and 10.8 +/- 0.8, minutes; 38 +/- 4, 63 +/- 12, 87 +/- 19, 100 +/- 13, 104 +/- 18, 137 +/- 27, and 157 +/- 18 minutes, respectively). CONCLUSION: Onset times were, in general, exponentially decreased with the increase in the lidocaine concentration. However, recovery times were lineary increased with the increase in the bupivacaine concentration. So, it should be kept in mind that rapid onset can only be obtained with the expense of substantial reduction in the duration of local anesthetic effect of the mixture, and vice versa.
Action Potentials
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Adult
;
Anesthesia
;
Anesthetics
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Anesthetics, Local
;
Bupivacaine
;
Humans
;
Lidocaine
;
Male
;
Nerve Block
;
Neural Conduction*
;
Perfusion
;
Rats, Sprague-Dawley
;
Sciatic Nerve
7.Stage Migration of Gastric Cancer According to the Extent of Lymph Node Dissection.
Sung Yong JANG ; Jong Myeong LEE ; Hang Cheol SHIN ; Sung Lim CHOI ; Woo Young KIM
Journal of the Korean Surgical Society 2002;63(5):390-396
PURPOSE: In this study, the authors attempted to evaluate the stage migration phenomenon according to D1 lymphadectomy and D2 lymphadectomy in the same patients. METHODS: A retrospective study was performed in 300 consecutive patients with gastric cancer who had undergone curative resection with nodal yields of D2 or more from 1994 to 1997. The lymph node status was evaluated in two different extents. Group B included patients with whole harvested regional lymph nodes (D2<) while group A include patients with perigastric lymph nodes (D1). Each group was staged by the number of involved lymph nodes according to the UICC-TNM stage (5th), and by the ratio of involved to resected lymph nodes. Stage migration and the difference of 5YSR were observed between the two groups. RESULTS: In staging by the number of involved lymph nodes, 25 cases (8.3%) of group B were staged up. According to the status by the ratio of involved lymph nodes, 14 cases (4.6%) of group B were staged up and 28 (9.3%) were staged down. CONCLUSION: In the staging of gastric cancer, adequate lymph node dissection was essential for accurate lymph node staging. In the cases of limited lymph node dissection, some extent of stage migration was considered assessing in the prognosis.
Humans
;
Lymph Node Excision*
;
Lymph Nodes*
;
Prognosis
;
Retrospective Studies
;
Stomach Neoplasms*
8.Prognostic utility of paraspinal muscle index in elderly patients with community-acquired pneumonia
Ga Ram LEE ; Seok Hoon KO ; Hang Sung CHOI ; Hoon Pyo HONG ; Jong Seok LEE ; Ki Young JEONG
Clinical and Experimental Emergency Medicine 2024;11(2):171-180
Objective:
This study investigated the associations between paraspinal muscle measurements on chest computed tomography and clinical outcomes of elderly patients with community-acquired pneumonia (CAP).
Methods:
This single-center, retrospective, observational study analyzed elderly patients (≥65 years) with CAP hospitalized through an emergency department between March 2020 and December 2022. We collected their baseline characteristics and laboratory data at the time of admission. The paraspinal muscle index and attenuation were calculated at the level of the 12th thoracic vertebra using chest computed tomography taken within 48 hours before or after admission. Univariable and multivariable logistic regression analyses were conducted to evaluate the association between paraspinal muscle measurements and 28-day mortality. Receiver operating characteristic (ROC) curve and area under the curve (AUC) analyses were used to evaluate the prognostic predictive power.
Results:
Of the 338 enrolled patients, 60 (17.8%) died within 28 days after admission. A high paraspinal muscle index was associated with low 28-day mortality in elderly patients with CAP (adjusted odds ratio, 0.994; 95% confidence interval, 0.992–0.997). The area under the ROC curve for the muscle index was 0.75, which outperformed the pneumonia severity index and the CURB-65 (confusion, urea, respiratory rate, blood pressure, age ≥65 years) metric, both of which showed an AUC of 0.64 in predicting mortality.
Conclusion
A high paraspinal muscle index was associated with low 28-day mortality in patients aged 65 years or older with CAP.
9.Prognostic utility of paraspinal muscle index in elderly patients with community-acquired pneumonia
Ga Ram LEE ; Seok Hoon KO ; Hang Sung CHOI ; Hoon Pyo HONG ; Jong Seok LEE ; Ki Young JEONG
Clinical and Experimental Emergency Medicine 2024;11(2):171-180
Objective:
This study investigated the associations between paraspinal muscle measurements on chest computed tomography and clinical outcomes of elderly patients with community-acquired pneumonia (CAP).
Methods:
This single-center, retrospective, observational study analyzed elderly patients (≥65 years) with CAP hospitalized through an emergency department between March 2020 and December 2022. We collected their baseline characteristics and laboratory data at the time of admission. The paraspinal muscle index and attenuation were calculated at the level of the 12th thoracic vertebra using chest computed tomography taken within 48 hours before or after admission. Univariable and multivariable logistic regression analyses were conducted to evaluate the association between paraspinal muscle measurements and 28-day mortality. Receiver operating characteristic (ROC) curve and area under the curve (AUC) analyses were used to evaluate the prognostic predictive power.
Results:
Of the 338 enrolled patients, 60 (17.8%) died within 28 days after admission. A high paraspinal muscle index was associated with low 28-day mortality in elderly patients with CAP (adjusted odds ratio, 0.994; 95% confidence interval, 0.992–0.997). The area under the ROC curve for the muscle index was 0.75, which outperformed the pneumonia severity index and the CURB-65 (confusion, urea, respiratory rate, blood pressure, age ≥65 years) metric, both of which showed an AUC of 0.64 in predicting mortality.
Conclusion
A high paraspinal muscle index was associated with low 28-day mortality in patients aged 65 years or older with CAP.
10.Prognostic utility of paraspinal muscle index in elderly patients with community-acquired pneumonia
Ga Ram LEE ; Seok Hoon KO ; Hang Sung CHOI ; Hoon Pyo HONG ; Jong Seok LEE ; Ki Young JEONG
Clinical and Experimental Emergency Medicine 2024;11(2):171-180
Objective:
This study investigated the associations between paraspinal muscle measurements on chest computed tomography and clinical outcomes of elderly patients with community-acquired pneumonia (CAP).
Methods:
This single-center, retrospective, observational study analyzed elderly patients (≥65 years) with CAP hospitalized through an emergency department between March 2020 and December 2022. We collected their baseline characteristics and laboratory data at the time of admission. The paraspinal muscle index and attenuation were calculated at the level of the 12th thoracic vertebra using chest computed tomography taken within 48 hours before or after admission. Univariable and multivariable logistic regression analyses were conducted to evaluate the association between paraspinal muscle measurements and 28-day mortality. Receiver operating characteristic (ROC) curve and area under the curve (AUC) analyses were used to evaluate the prognostic predictive power.
Results:
Of the 338 enrolled patients, 60 (17.8%) died within 28 days after admission. A high paraspinal muscle index was associated with low 28-day mortality in elderly patients with CAP (adjusted odds ratio, 0.994; 95% confidence interval, 0.992–0.997). The area under the ROC curve for the muscle index was 0.75, which outperformed the pneumonia severity index and the CURB-65 (confusion, urea, respiratory rate, blood pressure, age ≥65 years) metric, both of which showed an AUC of 0.64 in predicting mortality.
Conclusion
A high paraspinal muscle index was associated with low 28-day mortality in patients aged 65 years or older with CAP.