1.APPLIED-ANATOMIC STUDY ON MSCT OF GREATER OMENTUM IN CHINESE ADULTS
Acta Anatomica Sinica 2002;0(06):-
Objective To study radiological_anatomy of greater omentum and to address the related clinical implications,and to provide anatomic data for the radiological diagnosis and surgical application of greater omentum. Methods The anatomic distribution and morphology of the greater omentum as well as the anatomic relationship of the organs in the vicinity were analyzed by using axial,coronal,sagittal and 3D images from 16_detector row spiral CT scans of 60 individuals.We assessed the advantages of these images as well as the clinical significance.The data were recorded and analyzed by using SPSS11.5 software. Results 1.Advantages of three sections: axial section,the display of the fatty tissue and the anatomic distribution;coronal section,the vasculature; sagittal section,the anatomic relationship of neighbour organs.2.Three_dimensional reformatted images showed the return of the gastroepiploic vein.3.Gastrocolic trunk was revealed in 67.2% of cases.The free_hanging portion seemed to have the capability of 'migration': it located in the subphrenic spaces in 20.7% of cases and distributed in the right lower quadrant predominantly in 17.2% of cases.The CT value of fatty density within greater omentum was(-104.97?10.78)Hu and no statistical significance was found in the difference between greater omentum and the subcutaneous tissue.Conclusion Gastroepiploic vessel is the landmark for the location of greater omentum.Axial,coronal and sagittal sections together with 3D reconstruction images could produce a full display of greater omentum and provide valuable data for the radiological diagnosis as well as surgery of reconstruction, pancreas and portal hypertension.
2.Penetration Enhancers Screening for Compound Ketoconazole Gel
China Pharmacist 2016;19(4):685-688
Objective:To study the effect of caprylic/capric acid glycerides (Lab), propylene glycol (PG) and Azone on the transdermal behavior of ketoconazole and miconazole nitrate in compound ketoconazole gel, to screen appropriate penetration enhanc-ers. Methods:Using a RYJ-6A-type transdermal drug diffusion tester, the effects of Lab, PG and Azone at different concentrations on the transdermal behavior of ketoconazole and miconazole nitrate in compound ketoconazole gel were studied. Results:3% PG showed the most obvious penetration enhancement, which could increase the permeation of ketoconazole by 2. 004 times, and increase the pen-etration of miconazole nitrate by 1. 795 times, and the differences were statistically significant (P<0. 05). Conclusion:The penetra-tion effect of 3% PG is obvious, which can be applied in compound ketoconazole gel.
3.Clinical analysis of anomalies of female reproductive system associated with urinary system
Chinese Journal of Obstetrics and Gynecology 2001;0(08):-
Objective To determine the association of anomalies of female reproductive system with that of urinary system. Methods Two hundred and eighty-nine cases, including 59 with congenital vaginal inclined septum syndrome, 135 with septate uterus, 4 with unicornuate uterus, 13 with rudimentary horn of uterus, 58 with congenital absence of the uterus and vagina, 14 with imperforated hymen, and 6 with atresia of vagina, treated during the past 4 years, were analysed retrospectively. Results Anomalies of urinary system were more frequently found in patients with anisomerous anomalies of reproductive system(85. 53% , 65/76 cases). In 59 cases of congenital vaginal inclined septum syndrome, 43 had ipsilateral renal agenesis, 2 had one single pelvic kidney, 1 had bilateral horseshoe kidneys, 1 had left-side horseshoe kidney, 1 had one pair of renal pelvis and renal calices with ureters incorporated at middle and inferior segments on both sides. Ipsilateral renal agenesis was also seen in patients with rudimentary horn of uterus(14/14 cases) and unicornuate uterus(4/4 cases). However, there was no urinary system malformation seen in septate uterus patients (0/135 cases), imperforated hymen (0/16) and atresia of vagina (0/4 cases). Only 1 case of congenital absence of the uterus and vagina associated with ipsilateral renal agenesis. Conclusion Anomalies of reproductive ducts associated with renal malformations, especially anisomerous anomalies of reproductive system are not unusual. Early recognition and diagnosis is very important to prevention and treatment of such diseases.
5.Changes and significance of plasma neuropeptide Y in newborns with asphyxia
Dian HU ; Hang GU ; Zhijun JIN
Chinese Journal of Perinatal Medicine 1998;0(03):-
Objective To investigate the relationship between plasma neuropeptide Y(NPY) and asphyxia in newborns. Methods Thirty-seven patients with neonatal asphyxia (asphyxia group) and 33 healthy pregnant women(control group )in their third trimester were chosen. The concentrations of plasma NPY were measured by radioimmunoassay. Results The levels of NPY in umbilical artery plasma was (187.47? 46.63) ng/L in asphyxia group,and (115.33?29.42) ng/L in control group. There were significant difference between them ( P 0.05). Conclusions The neonatal asphyxia was associated with NPY. NPY might play an important role in the pathophysiological changes in neonatal asphyxia.
6.Primary malignant melanoma of the maxillary sinus misdiagnosed as bleeding polyp.
Wei HANG ; Gang LIU ; Jin-ling ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(8):688-689
Diagnostic Errors
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Female
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Humans
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Maxillary Sinus
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pathology
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Melanoma
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diagnosis
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Middle Aged
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Paranasal Sinus Neoplasms
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diagnosis
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Polyps
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diagnosis
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pathology
9.Concentration-responses relationships of intravenous propofol
Xiangrui WANG ; Dajin SUN ; Yannan HANG ; Chanran XU ; Zhengjun JIN ;
Chinese Journal of Anesthesiology 1996;0(07):-
To assess the concentration-responses relationships of propofol, 16 adult patient,ASA grade Ⅰ-Ⅱ,scheduled for upper abdominal operation, were randomly allocated to undergoing epidural block (group Ⅰ, n = 8)or combined anesthesia (group Ⅱ, n = 8) respectively. After a bolus injection of propofol 2.5mg ?kg, blood pressure (BP), heart rate (HR) and tidal volume (TV) were recorded, and drowsiness,amnesia,cooperation and orientation were evaluated by scorring scales in both groups. The venous samples were taken before and after the administration to measure the propofol plasma concentration by spectrofluorophotometric detector. The results revealed that there were no significant differences in pharmacokinetic parameters between two groups;the plasma concentration of propofol at 2. 5rag. L~(-1) was required for adequate anesthesia,and 1.5 to 1.9rag. L~(-1) for hypnosis,the patients were fully awake at 0.94?0.3mg. L~(-1); BP,HR and TV were significantly depressed at more than 2.0rag. L~(-1), and recovered to baseline at less than 1.5mg. L~(-1). It is suggested that there are good relationships between propofol plasma concentrations and its pharmacodynamic responses.
10.Modulating effect of calcium activated potassium and chloride channels on detrusor instability
Hang YANG ; Bo SONG ; Xiyu JIN ; Xin YANG ;
Journal of Third Military Medical University 2003;0(22):-
Objective To study the modulation alterations of calcium activated potassium channel (Kca) and calcium activated chloride channels (Clca) on detrusor instability(DI) and their roles in DI. Methods The detrusor instability (DI) animal model was established using female Wistar rats. Detrusor strips were obtained from normal and DI rats. The contraction frequency and amplitude of the strips were measured by an in vitro tension test. The actions of channel openers and blockers were studied. Results Spontaneous contraction frequency and amplitude of DI increased significantly. The block of big conductance calcium activated potassium channel(Bkca) by Iberiotoxin resulted in decrease of frequency but increase of amplitude in the control, but only increase of frequency in DI. The opener, NS1619, resulted in decreases of frequency and amplitude in the control, but only decreases of frequency in DI. The block of small conductance Kca (Skca) by apamin resulted in increases of frequency and amplitude in both control and DI groups, but the opener, Chlorzoxazone, resulted in decreases of frequency and amplitude in the control, but only decrease of frequency in DI. The contraction alterations of DI were significantly lower than those of the control no matter Kca was blocked or opened. NFA, a selective Clca blocker, resulted in no significant frequency and amplitude alteration in the control, but significant decrease in DI. Conclusion These results suggested that Kca and Clca play a critical role in the modulation of detrusor contraction, and the down regulation of Kca and up regulation of Clca suggests that disorder of calcium related regulation may play an important role in DI.