Objective: To explore the effects of acupuncture on nutritional status in patients in a persistent vegetative state. Methods: A prospective randomized controlled trial was designed. A total of 66 patients in a persistent vegetative state were randomized into a control group and an observation group, with 33 cases in each group. The control group was given conventional treatment plus enteral nutrition support. The observation group was treated with additional Tiao Shen Jian Pi acupuncture therapy (acupuncture for spirit-regulating and spleen-invigorating) based on the same interventions in the control group. Both groups were treated for 8 weeks. The levels of total protein (TP), prealbumin (PA), albumin (Alb), and hemoglobin (Hb) were measured before and after treatment. The upper arm circumference and skinfold thickness of triceps brachii were measured. And the intestinal flora and fecal short-chain fatty acids contents were determined.Results: After treatment, the levels of TP, PA, Alb, and Hb in the control group were decreased (P<0.05), while in the observation group, compared with those before treatment, the levels of TP, PA, Alb, and Hb had no statistical differences (P>0.05), and the levels were all higher than those in the control group (P<0.05). The upper arm circumference and skinfold thickness of triceps brachii in both groups decreased (P<0.05), and the values of these two items in the observation group were higher than those in the control group (P<0.05). In the control group, the contents of Bifidobacterium and Lactobacillus in feces decreased (P<0.05), and the content of Enterococcus increased (P<0.05). In the observation group, the contents of Bifidobacterium and Lactobacillus in feces increased (P<0.05), and the content of Enterococcus decreased (P<0.05). The differences between the two groups were statistically significant (P<0.05). In the control group, the total content of fecal short-chain fatty acids and the contents of acetic acid and butyric acid in feces decreased (P<0.05). In the observation group, the total content of fecal short-chain fatty acids and the contents of acetic acid and butyric acid in feces increased (P<0.05) and were all higher than those in the control group (P<0.05). Conclusion: Acupuncture can improve nutrition-related blood indicators in patients in a persistent vegetative state and delay the decrease of upper arm circumference and skinfold thickness of triceps brachii, which may be related to the regulation of intestinal flora and fecal short-chain fatty acids contents.

Objective To study the synergism effect of 131 I-Herceptin and high-energy X-ray on HER2 overexpressed breast cancer SK-BR-3 cells.Methods The protein expression and gene amplification of human epidermal growth factor receptor-2 ( HER2 ) in SK-BR-3 cells were identified by immunohistochemistry and fluorescence in situ hybridization ( FISH ) method, 131 I-Herceptin was prepared by iodogen method, and the IC15 concentration of 131 I-Herceptin on SK-BR-3 cell were selected by MTT method.The cells were divided into control group and drug group according to 131 I-Herceptin used or not, and were delivered five different doses of external irradiation (0,2,4 and 6Gy), and the synergism effect was detected by colonogenic assay.The cells were divided into blank group, drug group(131I-Herceptin), X-ray group(2 Gy external irradiation) and combination group (131I-Herceptin+2 Gy external irradiation), the apoptosis rate and death rate were detected by AO/EB method and cell cycle were detected by flow cytometry.Results The labling rate, radiochemical purity and specific radioactivity of 131 I-Herceptin were 86.8%, 93.9% and 868.3 μci/mg, respectively.The IC15 of 131 I-Herceptin was 15.625μci/mL.131 I-Herceptin and high-energy X-ray significantly reduced surviving fraction ( SF) ( F=628.888,F=964.97,P<0.05) and there were interactions between them (F=113.046,P<0.05).There were significant differences in apoptosis rate and death rate among blank group, drug group, X-ray group and combination group(F=103.324,F=13.33,all P<0.05),and there were significant differences of pairwise comparison (P<0.05).After irradiation and 131I-Herceptin administration, the cell cycle changed obviously from G1-phase to G2-and S-phase.Conclusion 131 I-Herceptin combined with high-energy X-ray has the synergism effect on HER2 overexpressed breast cancer SK-BR-3 cells.

Objective To explore the clinical effects of the packet therapy combined with Chinese prescrip-tion soaking in the treatment of patients with verruca plantaris,so as to provide clinical guidance and basis.Methods 101 patients with verruca plantaris were chosen as study objects,and they were divided into two groups,namely obser-vation group and control group.Observation group was treated by the packet therapy combined with Chinese prescrip-tion soaking,and control group was treated by Chinese prescription soaking.When they were cured for 4 weeks,the main symptoms and effective rate in the two groups were calculated and compared.For the recovery patients,when their drugs were withdrew for 8 weeks,the recurrence rate between the observation group and control group was compared.Results After being treated for 4 weeks,both of the skin lesion and pain degree between the observation group and control group had significant differences (Z=4.48,P<0.05;Z=4.18,P<0.05).The effective rates in the observation group and control group were 85.71% and 48.08%,respectively,and the difference between the two groups was statistically significant (χ2 =16.00,P<0.001).The recurrence rates in the observation group and control group were 13.33% and 27.27%,respectively,and the difference between the two groups was no statistically signifi-cant (P>0.05).Conclusion The packet therapy combined with Chinese prescription soaking is more effective than Chinese prescription soaking.

Objective To explore the differences of patient comfort and nursing workload between ultrasound guidance on upper arm placement of PICC and traditional placement of PICC, and to provide a reference for correct selection of catheter way. Methods Using a nonrandomized controlled study, a total of 1 116 patients were divided into the control group and the observation group, patients with traditional placement of PICC were set as the control group, and the patients with upper arm placement of PICC were named as the observation group. The patient comfort and workload of use and maintenance of PICC by nurses were compared between two groups. Results The incidence of catheter sliding out of PICC in the observation group was 1.9%(7/365), obviously higher than that of the control group, which was 0.3%(2/751), the difference was significant (χ2=8.37,P=0.007). The patient comfort had no statistical significance between two groups (t=2.13,P=0.082). The workload of use and maintenance of PICC in the observation group were (1.87±0.31) min and (9.16±1.07) min ,which were obviously higher than that of the control group [(0.85±0.16) min and(7.22±2.13) min] in winter (t=4.39, P=0.022;t=3.44, P=0.041), but there was no statistical significance between two groups in summer (P>0.05). Conclusions The workload of use and maintenance of PICC on upper arm placement was higher than traditional placement of PICC in winter, but the obvious differences of patient comfort and nursing workload in summer between the two PICC groups were not been found.

Objective To observe the effect of Bupiyichang pills combined with levocetirizine in the treatment of 56 patients with chronic urticaria,so as to provide clinical guidance and basis.Methods 118 patients with chronic urticaria were selected for our study,and after informed consent they were randomly divided into observation group and control group.The observation group were was treated by Bupiyichang pills combined with levocetirizine,and the control group were was treated by levocetirizine.When they were curingAfter treatment for 10,20,and 30 days,the effective rates in the two groups were calculated and compared with each other.And at the day before treating and the day after treating for 20 days,the serum IgE levels in each group was detected and compared.The falling ranges between the two groups were calculated and compared.Results When they were curing treated for 10,20,and 30 days,the effective rates in the observation group were 76.79％,94.64 ％,85.71％,respectively,which in those of the control group were 59.68％,74.19％,64.52％,respectively,the differences between the two groups were statistically significance significant (x2 =3.94,9.11,6.97,all P ＜ 0.05).At the day before treating and the day after treating for 20 days,the serum IgE levels in the observation group were (384.71 ± 65.62) U/mL and (214.59 ±40.71) U/mL respectively,the difference was statistically significance significant (t =10.93,P ＜ 0.05);and the serum IgE levels in the control group were (380.25 ± 67.81)U/mL and (256.99 ± 53.21)U/mL respectively,the difference was statistically significancesignificant (t =9.37,P ＜ 0.05).The falling ranges in the observation group and the control group were (170.12 ± 35.59) U/mL and (123.26 ± 53.31) U/mL respectively,the difference was statistically significance significant between the two groups (t =7.82,P ＜ 0.05).Conclusion Bupiyichang pills combined with levocetirizine is more effective than single medication of levocetirizine.

Objective To explore the effect of fiberoptic bronchoscopy lavage sputum suction on sputum aspiration in thoracic neoplasm patients with difficulty in postoperative expectoration .Methods Sixty thoracic neoplasm patients with postoperative expectoration difficulty who met the inclusion criteria were divided into the control group and the observation group according to the order number in ICU , each with 30 cases.The control group received the conventional sputum suction , and the observation group received the fiberoptic bronchoscopy lavage sputum suction on the basis of routine sputum suction .The effect of sputum aspiration was compared between the two groups .Results The cases of complications including mucosa damage , atelectasis, pulmonary infection were respectively 7, 2 and 5 cases in the observation group , and were lower than those in the control group , and the differences were statistically significant (χ2 =4.59 ,4.01 ,4.02 , respectively;P<0.05).The time of staying in the ICU was (6.25 ±2.58) d in the observation group, and was (8.29 ±3.52) d in the control group , and the difference was statistically significant ( t=2.56 ,P<0.05 ) .The average times of sputum aspiration every day were (5.0 ±2.0) in the observation group, and were lower than (7.5 ±2.8) in the control group , and the difference was statistically significant ( t =3.98 , P <0.01 ) .Conclusions The methods of fiberoptic bronchoscopy lavage sputum suction combined with routine clinical sputum suction can effectively maintain the normal lung ventilation function , and reduce the duration of hypoxemia and the occurrence of postoperative complications , and shorten the time of staying in the ICU .

Radiation therapy is the core treatment of tumor treatment, whose side effects are bothering clinical medical staff. This paper will explore the predictor of side effects benefiting clinical practice from macro and micro perspective, summarize research progress of predicting radiation side effects, and indicate the significance of nurses in the prediction of radiation side effects. On one hand, national nurses can develop local study according to research status quo, and on the other hand they can apply evidence-based predictor of side effects in clinical, perfect the assessment, intervention and health education process of radiation patient′s side effects, so as to promote the whole level of radiation nursing.

Objective To investigate the rapid recovery effectiveness of colorectal cancer patients with retaining stomach tube and existing problems. Methods Ninety-four patients with colorectal cancer in the hospital from March 2013 to April 2014 were randomly divided into fast track surgery group ( FTS group) without stomach tube and control group with retaining stomach tube, and two groups of postoperative exhaust time, length of hospital stay, and postoperative complications were compared. Results Compared with control group (5. 25 ± 1. 93) d, (14. 83 ± 4. 39)d, FTS group had shorter postoperative exhaust time (3. 49 ± 1. 78) d and
length of hospital stay (12. 06 ± 3. 22) d after surgery (t=2. 667 2, 3. 227 9;P<0. 05). The rate of digestive tract symptoms were significantly lower than the control group (χ2 =12. 536,P<0. 05). There were 12 cases suffered some digestive symptoms such as abdominal distension, diarrhea, nausea, vomiting in FTS group higher than 2 cases in the control group (χ2 =12. 536,P<0. 05). There were no significantly difference between the two groups in the postoperative complications (P >0. 05). Conclusions Colorectal cancer patients without gastric tube can obviously increase the incidence of gastrointestinal symptoms such as nausea and vomiting, but shorten the exhaust time and postoperative hospital stay, then the use of the gastric tube should follow the principle of individualization.

Objective To evaluate the value of CT guided percutaneous transthoracic needle biopsy (PTNB) for the diagnosis of lung ground‐glass opacity (GGO) with a Meta‐analysis .Methods Relevant English and Chinese language studies were searched on the PubMed ,EMBASE ,EBSCO ,OVID ,CNKI ,CBM ,VIP and WANFANG databases ,respectively .Data were calculated with software of Stata 12 .0 and Meta‐Disc 1 .4 .Results 6 of 82 retrieved studies were included (n=341) .The pooled sensitivity ,specifici‐ty ,LR+ ,LR- ,DOR ,AUC and 95% CI were 0 .92(0 .86-0 .95) ,0 .98(0 .85-1 .00) ,49 .03(5 .72-420 .18) ,0 .08(0 .05-0 .15) , 586 .24(65 .18-5 272 .83) and 0 .99(0 .98-1 .00) ,respectively .Conclusion CT guided PTNB can be used as one of the primary examination modalities for lung GGO with moderate sensitivity and specificity .

Objective To explore the scientific and effective communication education mode in the hospitalized tumor patients.Methods The patients were divided into two groups according to the time,and the control group received the traditional single dimension communication education,and the observation group received the multidimensional and systematic communication education.The patient satisfaction and the incidence of defects such as delayed CT examination,complaints operation cost and so on were compared between two groups.Results The satisfaction was 98.4％ (1 256/1 276) in the observation group,and was higher than 91.3％ (918/1 005) in the control group,and the difference was statistically significant (x2 =63.199,P ＜ 0.01).The nursing defects including delayed CT examination,complaints operation cost,failure to wear the wrist strap,use of electrical appliances and so on in the observation group were significantly decreased,and the total incidence rate of nursing defects in the observation group was 0.86％ (11/1 276),and was significantly lower than 17.8％ (179/1 005) in the control group,and the difference was statistically significant (x2 =34.78,P ＜ 0.01).Conclusions The multidimensional and systematic communication education can significantly improve the patient satisfaction,and can effectively reduce the nursing defects,and is worthy of wide clinical application.