No abstract available.
Epidermolysis Bullosa* ; Hand Deformities* ; Hand*

No abstract available.
Arthritis, Rheumatoid* ; Hand Deformities* ; Hand*

No abstract available.
Hand Deformities ; Humans ; Parkinsonian Disorders*

The variation of cleft hand deformity is so wide that there are many synonyms and classifications for it. Among them the classification of Manske based on the condition of first web space is mostly important in functional perspectives. In type IIb or III of the Manske's classification, in which the thumb web space is narrowed or syndactylized, release and re-creation of the thumb web space is extremely important for functional and aesthetic reconstruction. A representative procedure for correction of the type IIb or III cleft hand is Snow-Littler procedure in which the cleft is released as a palmar-based flap and then transferred to the released first web space for creation of the commissure. During the last 10 years, the authors experienced 38 cases of cleft hand deformity in 30 patients. Among them type IIb or III cleft hand was 5 cases in 4 patients. In all patients, 3rd digit was missing except 1 case and the first web spaces were completely syndactylized. We applied the Snow-Littler procedure for correction of these 5 cases. The functional outcomes and patients' satisfaction were followed up postoperatively. Thumb abduction was possible in range of 59.6 +/- 12.3 degrees. Intermetacarpal stabilities were well maintained and average pinch power was 2.3 +/- 0.8 Kg. In one case partial necrosis of the palmar-based flap tip was occurred. Careful design and preservation of the intrinsic blood supply of the palmar-based flap is extremely important for viability of the flap and successful results.
Classification ; Hand Deformities ; Hand* ; Humans ; Necrosis ; Thumb

For hand surgeons, the treatment of children with congenital differences of the upper extremity is challenging because of the diverse spectrum of conditions encountered, but the task is also rewarding because it provides surgeons with the opportunity to impact a child's growth and development. An ideal classification of congenital differences of the upper extremity would reflect the full spectrum of morphologic abnormalities and encompass etiology, a guide to treatment, and provide prognoses. In this report, I review current classification systems and discuss their contradictions and limitations. In addition, I present a modified classification system and provide treatment principles. As our understanding of the etiology of congenital differences of the upper extremity increases and as experience of treating difficult cases accumulates, even an ideal classification system and optimal treatment strategies will undoubtedly continue to evolve.
Hand Deformities, Congenital/*classification/pathology/*surgery ; Humans

Child ; Foot Deformities, Congenital ; genetics ; Hand Deformities, Congenital ; genetics ; Humans ; Male ; Pedigree

OBJECTIVE: To analyze the molecular genetics of a Chinese pedigree with congenital hand foot cleft. METHODS: Single nucleotide polymorphism microarray (SNP array) was used to analyze the whole genome copy number variation. RESULTS: SNP array analysis showed that there was a 433 kb repeat in 10q24.31-10q24.32 region, which contained LBX1, BTRC, POLL, OPCD and FBXW4 genes. CONCLUSION Microduplication of chromosome 10q24.31-10q24.32 may be the cause of congenital hand foot cleft in this pedigree.
China ; DNA Copy Number Variations/genetics* ; Foot Deformities, Congenital/genetics* ; Hand Deformities, Congenital/genetics* ; Humans ; Pedigree

Clinodactyly, as rare congenital malformation, refers to a curvature of a digit in a radial or ulnar direction in the coronal plane. The abnormality is inherited as an autosomal dominant trait. And its frequency was low, however, it was higher by accompanying other congenital anomaly. In present study, the frequency and genetic characteristics of clinodactyly were investigated. In 100 family (382 peoples), clinodactyly was found in 4.7% (n=18). All clinodactyly were bilateral and it was more frequent in female (6.8%) than male (2.6%), without statistical difference (p=0.056). Its inheritance was autosomal dominant trait in 80% (4/5) families, however, one family did not have any inheritance pattern. We described the frequency and clinical implication of clinodactyly, and this description will be lead to an improved understanding of its spectrum and inheritance.
Female ; Hand Deformities ; Humans ; Inheritance Patterns ; Male ; Prevalence* ; Wills

The treatment of a brachymetacarpia using a distraction osteogenesis was mostly single, unilateral pattern. In case of multiple brachymetacarpia, single-stage lengthening or rapid distraction lengthening with a bone graft were usually used. Multiple brachymetacarpia treated by distraction osteogenesis is rarely reported. We report a case of a 15-year-old female presented with bilateral multiple brachymetacarpia treated by distraction osteogenesis simultaneously without complications. Also, we have evaluated the clinical results and factors which influence the clinical results.
Adolescent ; Brachydactyly ; Female ; Hand Deformities ; Humans ; Osteogenesis, Distraction* ; Transplants

Hand Deformities ; pathology ; Humans ; Klippel-Feil Syndrome ; pathology ; Thumb