1.Clinico-statistical analysis of the laryngeal polyp and nodule.
Han Woong JUNG ; Yang Sun LEE ; Jae Yul PARK ; Sin Il KWAK ; Jung Jae SEO
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(3):395-402
No abstract available.
Polyps*
2.Primary Primitive Neuroectodermal Tumor of the Kidney.
Woong Kyu HAN ; Won Jae YANG ; Sung Yong CHO ; Seung Chul YANG ; Woo Hee JUNG
Korean Journal of Urology 2000;41(3):456-458
No abstract available.
Kidney*
;
Neuroectodermal Tumors, Primitive*
3.Changes of Plasma Inactive Renin in Newborn Infant and Children.
Pyoung Han HWANG ; Woong Kyou PARK ; Heon Sook LEE ; Jung Soo KIM ; Kyung Woo CHO
Journal of the Korean Pediatric Society 1984;27(9):872-876
No abstract available.
Child*
;
Humans
;
Infant, Newborn*
;
Plasma*
;
Renin*
4.A case of polyethemia associated CAPD on a chronic renal failure patient.
Chan Su JEONG ; Jung Woong LEE ; Kyung Kun HAN ; Jong Hyun KIM ; Young Sung JAE
Korean Journal of Nephrology 1992;11(4):482-486
No abstract available.
Humans
;
Kidney Failure, Chronic*
;
Peritoneal Dialysis, Continuous Ambulatory*
5.Coronary Stent Implantation for Restenosis after PTCA.
Won Heum SHIM ; Jung Han YOON ; Tack Jong HONG ; Woong Ku LEE
Korean Circulation Journal 1991;21(3):598-605
We report the implantation of a balloon-expandable intravascular stent at proximal left anterior decending artery in a patients suffered from Canakian functional class III angina for 8 years. The patient received 3 times percutaneous transluminal coronary angioplasty at proximal left anterior descending and circumflex artery without benefits. Repeated angiography revealed restenosis at proximal left anterior descending artery. Atherectomy was tried with transluminal extraction catheter(TEC) with luminal dissection and coronary bypass graft followed. occluded vein grafts were defined by follow-up angiography and chest pain recurred. No residual stenosis or thrombosis was documented in 24 hour follow-up angiography and the patient was discharged without symptom at 10 days after stenting.
Angiography
;
Angioplasty, Balloon, Coronary
;
Arteries
;
Atherectomy
;
Chest Pain
;
Constriction, Pathologic
;
Follow-Up Studies
;
Humans
;
Phenobarbital
;
Stents*
;
Thrombosis
;
Transplants
;
Veins
6.Diagnostic Challenge of Hemorrhagic Fever with Renal Syndrome on Admission before its Serological Confirmation.
Korean Journal of Nephrology 2004;23(1):82-91
PURPOSE: The purpose of this study was to look for possible changes from typical clinical features of 5 sequential clinical phases described in 1950s. METHODS: The clinical features and laboratory data of hemorrhagic fever with renal syndrome (HFRS) with acute renal failure (ARF) and its subdivided 2 groups of correct and incorrect impression of HFRS on admission before the serological confirmation were reevaluated in 35 patients admitted at a single tertiary center from 1995 to 2000. RESULTS: We experienced the high failure rate (74%, 26/35) to recognize HFRS as the cause of ARF on admission. On admission, fever was present in all patients (100 %), and thirty three (94%) had either single or combined gastrointestinal symptoms. However, no one had clinical shock and only 4 patients (11%) had hypotension. Also, oliguria was noted only in 5 patients (14%) during the first 24 hrs on admission. When compared between 2 groups of correct (n=9) and incorrect impression of HFRS (n=26), febrile (100% vs 100%) and gastrointestinal symptoms (89% vs 96%) were present high both but hematologic (67% vs 23%) and hemodynamic signs (67% vs 4%) were much less present in the latter. The patients of incorrect impression on admission were admitted more than half (14/26, 54%) under non-renal care, and were exposed to antibiotics (46%) and even steroids (15%), respectively. In addition, these patients with incorrect impression on admission showed the unwanted outcomes of longer hospitalization than those with correct impression of HFRS (mean+/-SD, 21+/-3 vs. 12+/-4 days, p<0.01). CONCLUSION: Its well awareness of the changing clinical features in endemic area of HFRS would avoid overlooking Hantaviruses as a causal agent of ARF on the initial admission stage of HFRS leading to unnecessary treatments and longer hospitalization.
Acute Kidney Injury
;
Anti-Bacterial Agents
;
Diagnosis
;
Fever
;
Hantavirus
;
Hemodynamics
;
Hemorrhagic Fever with Renal Syndrome*
;
Hospitalization
;
Humans
;
Hypotension
;
Oliguria
;
Shock
;
Steroids
7.Significance of the giftec as a screening test for cervical cancer.
Heung Ki KIM ; Sang Kyun HAN ; Woong Shick AHN ; Sung Eun NAMKOONG ; Jae Keun JUNG ; Seung Jo KIM
Korean Journal of Obstetrics and Gynecology 1991;34(4):515-522
No abstract available.
Mass Screening*
;
Uterine Cervical Neoplasms*
8.Comparison of Outcome between Double and Inoue Balloon Techniques for Percutaneous Mitral Valvuloplasty in Mitral Stenosis: A Randomized Prospective Study.
Won Heum SHIM ; Jung Han YOON ; Yang Soo JANG ; Seung Yun CHO ; Seong Soon KIM ; Woong Ku LEE
Korean Circulation Journal 1992;22(5):747-753
BACKGROUND: Since the nonsurgical treatment of mitral stenosis using a single balloon has been introduced by Inoue et al. in 1984. percutaneous mitral valvuloplasty has became an accepted therapeutic modality for selected patients with mitral stenosis. Zeibag et al. demonstrated the double balloon technique showed a better outcome than the single balloon in obtainning the optimal mitral valve area. On the other hand, there are several reports that single balloon technique was comparable with the double balloon technique. Therefore, there are still controversies in efficacy, benefit and complications between balloon techniques. METHOD: To compare the efficacy and complications of percutaneous mitral valvuloplasty with the double balloon or the Inoue balloon technique, 40 patients were studied consecutively by random method in selecting the balloon technique. RESULTS: In all cases, percutaneous mitral valvulopasty was performed successfully. Optimal outcome defined as mitral valve area larger than 1.5cm2 was obtained in 12 cases out of 16(75%) in double balloon group and 15 out of 24(63%) in Inoue balloon group(p=NS). Mitral valve area was significantly increased after valvulopasty in both technique but there was no different between both groups(Mean+/-SD ; 0.9+/-0.3 to 1.7+/-0.2 vs 0.9+/-0.2 to 1.9+/-0.2cm2). There were also hemodynamic improvement significantly in mean mitral gradient(MG). pulmonary artery pressure (PAP) and left atrial pressure(LAP) after PMV but there were no difference between groups (18+/-8 to 7+/-2 vs 21+/-13 to 9+/-4 mmHg for MG. 29+/-12 to 22+/-9 vs 28+/-9 to 18+/-5mmHg for PAP and 22+/-8 to 11+/-5 vs 21+/-6 to 11+/-4 for LAP respectively). Mitral requrgitation greater than grade 2 occurred in 2 cases of the double balloon group and one case of the Inoue balloon group(p=NS). New development of atrial shunt was found in 3 cases in both groups. CONCLUSIONS: The double and Inoue balloon techniques were quite comparable in immediate outcome and complications.
Hand
;
Hemodynamics
;
Humans
;
Mitral Valve
;
Mitral Valve Stenosis*
;
Prospective Studies*
;
Pulmonary Artery
9.The Effect of Bacterial Lipopolysaccharide on the Lymphokine Production of the T Lymphocytes.
Hyung Bae MOON ; Ki Jung YUN ; Won Chul HAN ; Chae Woong LIM ; Hyuk Nyun KWON ; Young Soon PARK
Korean Journal of Pathology 1997;31(3):244-251
It is well known that the murine T helper cell clones are divided by their lymphokine secretory activities. One is the Th-1 cell, producing IL-2 and IFN after stimulation and the other is the Th-2 cell, producing the IL-4 and IL-5. This study was undertaken to evaluate the immunomodulatory properties of the bacterial lipopolysaccharide(LPS) on the lymphokine production in vivo and in vitro. The results were as follows: There were no effects on the lymphokine secretion by the in vitro treatment of the LPS. The in vivo treatment of the LPS decreases the capability of the production of IL-2 and IFN , whereas it increases the capability of IL-4 production. The altered capacity of the lymphokine production was recovered about 2 weeks after the treatment of the LPS. There were no differences on the lymphokine production between E-coli LPS and salmonella LPS. The capacity of the lymphokine production was the same in the treatment of a non-heated LPS or heated-LPS. The lymphokine production of the mice which were desensitized by the long term treatment of the LPS was not different from the control mice. The in vitro treatment of RU486 can block the alterations of the lymphokine production after the treatment of the LPS. In summary, one can tell that the LPS increases the secretion of the IL-4 through the endogenous secretion of the glucocorticoids.
Animals
;
Clone Cells
;
Glucocorticoids
;
Interleukin-2
;
Interleukin-4
;
Interleukin-5
;
Mice
;
Mifepristone
;
Salmonella
;
T-Lymphocytes*
;
T-Lymphocytes, Helper-Inducer
10.The Effect of Doxorubicin and Allopurinol in Chemomyectomy.
Won Kyun JUNG ; Han Woong KO ; Dong Hee KANG ; Sang Hwan KOO ; Seung Ha PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2004;31(3):351-357
This study was designed to identify doxorubicin as a permanent chemomyectomy agent that overcomes reversible effect of botulinum toxin A. Doxorubicin was assessed for its ability to bring about a permanent chemomyectomy and the effects of pretreatment were observed to assess its ability to prevent any complications brought about by doxorubicin. A total of thirteen rabbits were assigned to the control group(n=3) and two experimental groups(n=5 for each group). To investigate the myopathic changes following the injections of the agent, both orbicularis oculi muscles of the lower eyelids of each rabbit in the control group were directly injected with single dose of 0.2ml normal saline. Group I were injected with 0.5mg/0.2ml of doxorubicin into the right eyelid and 1.0 mg/0.2 ml of doxorubicin into the left. Group II were given an intravenous injection of 35mg/kg of allopurinol as the pretreatment, then 30minutes later injected with 0.5mg/0.2ml of doxorubicin into the right and 1.0mg/ 0.2ml of doxorubicin into the left. The rabbits were examined daily to monitor the onset, duration and size of skin necrosis and histologically examined two and four months after initial injections. The myopathic change after doxorubicin injection was persistent and irreversible. The dose related effects of doxorubicin chemomyectomy were confirmed by the histologic finding. Skin necrosis occurred in all cases of doxorubicin injection(both 0.5mg and 1.0mg), however the allopurinol pretreatment decreased the size of the skin necrosis in case of the high dose(1.0mg) of doxorubicin. The combined use of allopurinol and doxorubicin reduced the myopathic change more effectively than doxorubicin use alone. Further study is needed to determine optimal dose and administration method, which we feel will contribute to safer and permanent chemomyectomy.
Allopurinol*
;
Botulinum Toxins
;
Doxorubicin*
;
Eyelids
;
Injections, Intravenous
;
Muscles
;
Necrosis
;
Rabbits
;
Skin