1.Mitral valve reconstruction.
Jay Won LEE ; Han Ku DO ; Taek Hee CHANG ; Sang Rok CHO ; Myung Hoon NA
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(3):191-195
No abstract available.
Mitral Valve*
2.Mean Corpuscular volume in alcoholics.
Seog Woon KWON ; Seong Ho PARK ; Duk Lyul NA ; Sang Woon CHOI ; Han Ik CHO
Korean Journal of Clinical Pathology 1992;12(3):299-303
No abstract available.
Alcoholics*
;
Erythrocyte Indices*
;
Humans
3.Effect of metronome rates on the quality of bag-mask ventilationduringmetronome-guided30:2cardiopulmonary resuscitation: A randomized simulation study
Na Ung JI ; Han Kuk SANG ; Choi Cho PIL ; Shin Hyuk DONG
World Journal of Emergency Medicine 2017;8(2):136-140
BACKGROUND:Metronome guidance is a feasible and effective feedback technique to improve the quality of cardiopulmonary resuscitation (CPR). The rate of the metronome should be set between 100 to 120 ticks/minute and the speed of ventilation may have crucial effect on the quality of ventilation. We compared three different metronome rates (100, 110, 120 ticks/minute) to investigate its effect on the quality of ventilation during metronome-guided 30:2 CPR. METHODS:This is a prospective, randomized, crossover observational study using a RespiTrainer?r. To simulate 30 chest compressions, one investigator counted from 1 to 30 in cadence with the metronome rate (1 count for every 1 tick), and the participant performed 2 consecutive ventilations immediately following the counting of 30. Thirty physicians performed 5 sets of 2 consecutive (total 10) bag-mask ventilations for each metronome rate. Participants were instructed to squeeze the bag over 2 ticks (1.0 to 1.2 seconds depending on the rate of metronome) and deflate the bag over 2 ticks. The sequence of three different metronome rates was randomized. RESULTS:Mean tidal volume significantly decreased as the metronome rate was increased from 110 ticks/minute to 120 ticks/minute (343±84 mL vs. 294±90 mL, P=0.004). Peak airway pressure significantly increased as metronome rate increased from 100 ticks/minute to 110 ticks/minute (18.7 vs. 21.6 mmHg, P=0.006). CONCLUSION:In metronome-guided 30:2 CPR, a higher metronome rate may adversely affect the quality of bag-mask ventilations. In cases of cardiac arrest where adequate ventilation support is necessary, 100 ticks/minute may be better than 110 or 120 ticks/minute to deliver adequate tidal volume during audio tone guided 30:2 CPR.
4.Intravenous Immunoglobulin Therapy in Guillain-Barre Syndrome.
Kyung Won CHO ; Won Young JUNG ; Jeong Gyun NA ; Gun Han LIM
Journal of the Korean Neurological Association 1994;12(4):709-714
High dose intravenous immunoglobulin (IVIg) therapy can improve the clinical course of several immune mediciated diseases. We evaluated clinical effects and side effects of IVIg in Guillain-Barre syndrome (GBS). 19 Patients with GBS were studied prospectively in a placebo-controlled trial. 11 Patients were received high dose IVIg (400mg/kg for 5 days) and controls received only conservative treatment. The disability scores using modified Rankin scores before and after treatment of each group were compared. Four weaks later, mean Rankin Score of IVIg group was 2.5 + 0.7 and control group was 3.3+ 0.5which showed significant difference(p<0.05). There were no serious advers effer of promote early improvement with safety in acute phase of Guillan-Barre syndrome.
Guillain-Barre Syndrome*
;
Humans
;
Immunization, Passive*
;
Immunoglobulins*
;
Immunoglobulins, Intravenous
;
Prospective Studies
5.Statin and Ezetimibe Combination Therapy Decreases Mean Platelet Volume Compared to Statin Monotherapy.
Jun beom LEE ; Gyeong Seon KIM ; Han na CHO
Journal of Stroke 2017;19(1):109-110
No abstract available.
Ezetimibe*
;
Hydroxymethylglutaryl-CoA Reductase Inhibitors*
;
Mean Platelet Volume*
6.The Correlation between the Radiological Changes and the Level of Transforming Growth Factor-beta1 in Patients with Pulmonary Tuberculosis.
Yongseon CHO ; Yang Deok LEE ; Wook CHO ; Dong Jib NA ; Min Soo HAN
Tuberculosis and Respiratory Diseases 2006;60(3):297-303
BACKGROUND: Pulmonary tuberculosis is frequently accompanied with complications such as bronchiectasis, cavities, fibrosis and a deterioration of the lung function. However, there is little information available on the pathogenesis of these complications in pulmonary tuberculosis. Among the many factors involving in tissue remodeling, transforming growth factor-beta1 (TGF-beta1) is a potent stimulus of the extracellular matrix fomation and a mediator of potential relevance for airway wall remodeling. Therefore, this study examined the relationship between the radiological changes and the TGF-beta1 level in patients with pulmonary tuberculosis. METHODS: Serum and bronchoalveolar lavage fluid (BALF) were collected from total of 35 patients before treating them for active pulmonary tuberculosis, and the TGF-beta1 levels were measured using an enzyme-linked immunosorbent assay (ELISA). The BALF levels were recalculated as the epithelial lining fluid (ELF) levels using the albumin method. pulmonary function test (PFT) and high resolution computed tomography (HRCT) were performed before and after treatment. RESULTS: There was a strong correlation between the serum TGF-beta1 level and the presence of cavities (r=0.404, p=0.006), even though the BAL TGF-beta1 level showed a weak correlation with complications. In addition, there was no correlation between the TGF-beta1 levels before treatment and the changes in the PFT and HRCT during treatment. CONCLUSION: There is a correlation between the serum TGF-beta1 level and cavity formation in pulmonary tuberculosis before treatment. However, further study will be needed to confirm this.
Bronchiectasis
;
Bronchoalveolar Lavage Fluid
;
Enzyme-Linked Immunosorbent Assay
;
Extracellular Matrix
;
Fibrosis
;
Humans
;
Lung
;
Respiratory Function Tests
;
Transforming Growth Factor beta1
;
Tuberculosis, Pulmonary*
7.Comparison of diagnostic performances of slow-pull suction and standard suction in endoscopic ultrasound-guided fine needle biopsy for gastrointestinal subepithelial tumors
Joon Seop LEE ; Chang Min CHO ; Yong Hwan KWON ; An Na SEO ; Han Ik BAE ; Man-Hoon HAN
Clinical Endoscopy 2022;55(5):637-644
Background/Aims:
Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is integral to the diagnosis of gastrointestinal (GI) subepithelial tumors (SETs). The impact of different EUS-FNB tissue sampling techniques on specimen adequacy and diagnostic accuracy in SETs has not been fully evaluated. This study aimed to compare the diagnostic outcomes of slow-pull (SP) and standard suction (SS) in patients with GI SETs.
Methods:
In this retrospective comparative study, 54 patients were enrolled. Medical records were reviewed for location and size of the target lesion, FNB needle type/size, technical order, specimen adequacy, diagnostic yield, and adverse events. The acquisition rate of adequate specimens and diagnostic accuracy were compared according to EUS-FNB techniques.
Results:
The mean lesion size was 42.6±36.4 mm, and most patients were diagnosed with GI stromal tumor (75.9%). The overall diagnostic accuracies of the SP and SS techniques were 83.3% and 81.5%, respectively (p=0.800). The rates of obtaining adequate core tissue were 79.6% and 75.9%, respectively (p=0.799). No significant clinical factors affected the rate of obtaining adequate core tissue, including lesion location and size, FNB needle size, and final diagnosis.
Conclusions
SP and SS had comparable diagnostic accuracies and adequate core tissue acquisition for GI SETs via EUS-FNB.
8.Geometric Calibration of Cone-beam CT System for Image Guided Proton Therapy.
Jin Sung KIM ; Min Kook CHO ; Young Bin CHO ; Han Bean YOUN ; Ho Kyung KIM ; Myounggeun YOON ; Dongho SHIN ; Sebyeung LEE ; Re Na LEE ; Sung Yong PARK ; Kwan Ho CHO
Korean Journal of Medical Physics 2008;19(4):209-218
According to improved radiation therapy technology such as IMRT and proton therapy, the accuracy of patient alignment system is more emphasized and IGRT is dominated research field in radiation oncology. We proposed to study the feasibility of cone-beam CT system using simple x-ray imaging systems for image guided proton therapy at National Cancer Center. 180 projection views (2,304x3,200, 14 bit with 127 micrometer pixel pitch) for the geometrical calibration phantom and humanoid phantoms (skull, abdomen) were acquired with 2degrees step angle using x-ray imaging system of proton therapy gantry room (360degrees for 1 rotation). The geometrical calibration was performed for misalignments between the x-ray source and the flat-panel detector, such as distances and slanted angle using available algorithm. With the geometrically calibrated projection view, Feldkamp cone-beam algorithm using Ram-Lak filter was implemented for CBCT reconstruction images for skull and abdomen phantom. The distance from x-ray source to the gantry isocenter, the distance from the flat panel to the isocenter were calculated as 1,517.5 mm, 591.12 mm and the rotated angle of flat panel detector around x-ray beam axis was considered as 0.25degrees. It was observed that the blurring artifacts, originated from the rotation of the detector, in the reconstructed toomographs were significantly reduced after the geometrical calibration. The demonstrated CBCT images for the skull and abdomen phantoms are very promising. We performed the geometrical calibration of the large gantry rotation system with simple x-ray imaging devices for CBCT reconstruction. The CBCT system for proton therapy will be used as a main patient alignment system for image guided proton therapy.
Abdomen
;
Artifacts
;
Axis, Cervical Vertebra
;
Calibration
;
Cone-Beam Computed Tomography
;
Humans
;
Isothiocyanates
;
Proton Therapy
;
Protons
;
Radiation Oncology
;
Skull
9.A Case of Spontaneous Pneumomediatsinum during Taekwondo.
Ho Seok JEON ; Min Soo HAN ; Kyung Min MOON ; Yang Deok LEE ; Yongseon CHO ; Dong Jib NA
Tuberculosis and Respiratory Diseases 2008;65(3):222-224
Spontaneous pneumomediastinum is defined as a clinical syndrome thatos characterized by the presence of air in the mediastinal space, which is not due to an old previous injury or surgery. The condition is caused by a sustained increase in the intraalveolar and intrabronchial pressure with extravasated air dissecting along the perivascular spaces of the mediastinum. This is an uncommon complication of sports activity. The most common symptom is chest pain. This diagnosis should be considered for younger people who present with pleuritic chest pain or dyspnea and a characteristic crackling feel (known as subcutaneous crepitation) when touching of the skin covering the chest wall or neck, and they look otherwise well with normal vital signs. Usually no treatment is required, but the mediastinal air will be absorbed faster if the patient inspires high concentrations of oxygen. We present here a case of spontaneous pneumomediastinum that occurred during a Taekwondo match, along with a review of the relevant literature.
Chest Pain
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Dyspnea
;
Humans
;
Mediastinal Emphysema
;
Mediastinum
;
Neck
;
Oxygen
;
Skin
;
Sports
;
Thoracic Wall
;
Vital Signs
10.Assessment of Environmental Monitoring Items for Mixed Organic Solvents in Work Place.
Soo Hun CHO ; Ho Jang KWON ; Mi Na HA ; Sang Hwan HAN ; Yong Hyeon YIM ; Sung Tae OH
Korean Journal of Occupational and Environmental Medicine 1994;6(2):259-269
Ambient air monitoring(environmental monitoring) and biological monitoring of mixed organic solvents exposure have been used in exposure assessment of these compounds in the work environment. Environmental monitoring is more useful when assessing low level exposure to these compounds. The specific objectives of this study were to measure air organic solvent levels in the work environment, to test the agreement of items measured in this study with items which have been reported to the administrative agency, and finally to evaluate the appropriateness of environmental monitoring items. The study subjects were 13 small companies in which less than 300 employees were working and presumably exposed to mixed organic solvents(e.g. automotive repair and painting, 6; textile dyeing, 2; printing, 2; electronics, etc, 3). Personal air samplings were performed by the flow-lite sampling pump(MSA) and the 600mg charcoal tube with air velocity of 100ml/min for qualitative analysis and 2l/min for quantitative analysis. Samples were analysed by gas chromatography/mass spectrometry(Hewlett-Packard 5890/5970). High levels of toluene, n-hexane, and MIBK were detected in most study companies and low levels of ethylbenzene, xylene, n-butylacetate were also detected. When these measured items were compared with those of reported items, only 6 of 13 companies showed relatively good agreement between them. Two companies failed to report items exceeding the limit value. In conclusion, qualitative analysis of ambient air organic solvents seemed to be as important as quantitative analysis of these compounds and a periodic evaluation of monitoring items reported to the administrative agency should be required.
Charcoal
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Environmental Monitoring*
;
Humans
;
Mass Spectrometry
;
Paint
;
Paintings
;
Solvents*
;
Textiles
;
Toluene
;
Workplace*
;
Xylenes