A hemangiopericytoma is a rare soft tissue sarcoma that originates from pericytes. This neoplasm can occur in any part of the body but their frequent sites of origin are reported to be the lower extremities, pelvis, retroperitoneum, head, neck and trunk. A hemangiopericytoma may be curable by a surgical resection but its prognosis is poor when it recurs. Distant metastases rarely occur and the most commonly affected organs are the lung and bone. At CT, a hemangiopericytoma is typically depicted as a hypervascular tumor with a delayed fill-in of contrast enhancement from the periphery. We encountered a case of hemangiopericytoma that metastasized to the liver. We describe the radiological findings of the metastatic hemangiopericytoma of the liver.
Head ; Hemangiopericytoma* ; Liver* ; Lower Extremity ; Lung ; Neck ; Neoplasm Metastasis ; Pelvis ; Pericytes ; Prognosis ; Sarcoma

A 65-year-old female, who suffered with a longstanding headache, was admitted to our hospital. MR imaging and digital subtraction angiography (DSA) demonstrated a vascular fat-containing mass in the right cerebellopontine angle. The lesion was surgically removed and the diagnosis of angiolipoma was established. The symptoms subsided after the operation.
Aged ; Angiography ; Angiography, Digital Subtraction ; Angiolipoma* ; Brain ; Cerebellopontine Angle* ; Diagnosis ; Female ; Headache ; Hemangioma ; Humans ; Magnetic Resonance Imaging

Eosinophilic gasteroenteritis is an uncommon disease with variable clinical features characterized by eosinophilic infiltration. Clinical manifestations range from non-specific gastrointestinal complaints such as nausea, vomiting, crampy abdominal pain, and diarrhea to specific findings such as malabsorption, protein loosing enteropathy, luminal obstruction, eosinophilic ascites and effusion. We report here on a case of eosinophilic gastroenteritis causing enterobiliary fistula which is an extremely unusual complication.
Aged ; Biliary Fistula/diagnosis/*etiology ; Cholangiopancreatography, Magnetic Resonance ; Duodenal Diseases/*etiology ; Eosinophilia/complications ; Gastroenteritis/*complications ; Humans ; Intestinal Fistula/diagnosis/*etiology ; Male

Conventional radiographs and simple CT scans fail to provide accurate information about the structural integrity of a fracture site. In recent years, special 3-dimensional CT scanning has been progressively developed, and we applied this technique to thoracolumbar compression fractures. Posterolateral spinal fusion with iliac bone graft was attempted in all patients; Comparative pre- and post-operative change in these fractures was then an-alysed, using 3-dimensional CT. The results of this study suggest that this imaging is a useful non-invasive technique to assess compression fracture and determine prognosis.
Fractures, Compression* ; Humans ; Prognosis ; Spinal Fusion ; Tomography, X-Ray Computed ; Transplants

Statistical observation was made on 809 in-patient in the Department of Urology, College of Medicine, Hanyang University from May 3, 1972 to December 31, 1976.
Humans ; Inpatients ; Urology

The authors report a rare case of gunshot injury to the head by a nail-gun which was treated by stereotactic surgery. In the case, a 23-year-old male patient, presented with semicomatose mentality and decerebrated rigidity. The large nail was located in the 3rd ventricular area in the mid-line with vertical stature. The entry point was identified 1cm anterior to the coronal suture line and just lateral to the sagittal suture line. The foreign body was removed stereotactically with the guidance of gluoroscope. But the died of initial severe brain damage.
Brain ; Craniocerebral Trauma ; Foreign Bodies ; Head* ; Humans ; Male ; Sutures ; Young Adult

PURPOSE: To establish the basis for a non-invasive and non-destructive assessment of the mechanical properties during natural fracture healing by analyzing the vibrational property of the fracture healing and comparing the vibrational property, the bone healing status (as determined by X-ray) and the mechanical strength parameters. MATERIALS AND METHODS: The tibial shafts of rabbits were broken under general anesthesia. The rabbits were sacrificed at 2, 4, 6 weeks after the fracture, then X-rays of the fractured tibias were sequentially taken to detect the fracture healing. The vibration mode and the biomechanical strength were measured. RESULTS: According to the results of a multiple regression analysis, the standardized coefficients of callus, apposition, lateral angulation, DAMP1, FREQ1 in the fractured tibias, were -0.80, -0.23, -0.21, -0.25, -0.25. In normal contralateral tibias, the standardized coefficients of the area, FREQ1, DAMP1, FREQ2, DAMP3 were -0.73, 0.28, 0.41, 0.39, -0.25. CONCLUSION: A monitoring of the fracture healing process that utilizes the frequency response function is thought to be useful in detecting the early phase of healing within 4 weeks. Additional studies on the vibrational characteristics of the healing bones after a clinical union or after simillar pathologies should be pursued so that future diagnostic applications ca be made.
Anesthesia, General ; Bony Callus ; Fracture Healing ; Fractures, Bone* ; Pathology ; Rabbits ; Tibia ; Vibration

Human leukocyte antigen (HLA) class II molecules are polymorphic cell surface glycoproteins that are crucial for the cellular interaction in immune response. The expression of class II molecules is regulated in a tissue-specific and cytokine-inducible manner, and is mainly restricted to the antigen presenting cells. However, some tumor cells also express class II molecules, and in some class-II-negative tumor cells, class II expression is inducible by interferon (IFN)-gamma. However, their expression varies, even though the tumor cells originate from the same histological origin; some tumor cells show strong expression, others show weak or no expression. To determine whether this differential expression of class II molecules on tumor cells is transcriptionally regulated, FACS analysis and Northern hybridization were performed using a panel of melanoma cell lines, IGR3, Malme-3M, SK-Mel-24, and SK-Mel-28 to analyze the cell surface expression and mRNA transcription rate of HLA-DR before and after treatment with IFN-gamma. FACS analysis showed that before IFN-gamma treatment, IGR3 and Malme-3M cells barely expressed HLA-DR. On the contrary, almost all of the SK-Mel-24 cells (> 90%) and a relatively high rate (> 50%) of SK-Mel-28 cells expressed HLA-DR. After IFN-gamma treatment, HLA-DR expression was induced in Malme-3M cells and SK-Mel-28 cells which displayed elevated levels of HLA-DR expression in a time-dependent manner. However, IGR3 cells never responded to IFN-gamma. Northern analysis showed that treatment with IFN-gamma led to the steady-state mRNA augmentation of the HLA-DR gene in Malme-3M and SK-Mel-28, whereas in IGR3, IFN-gamma did not augment the transcriptional rate of the HLA-DR gene. To further clarify this differential modulation, sequencing analysis of PCR product of the HLA-DR proximal promoter region was done, since the transcription rate of the class II gene is controlled by the well-conserved proximal promoter region. Six independent clones from PCR products of the HLA-DRA proximal promoter region and 16 clones from PCR products of the HLA-DRB proximal promoter region were isolated from the above cell lines and sequenced. Comparison of the nucleotide sequences of all 6 clones of DRA promoter showed that the sequences are extremely similar in both regulatory sequences and their intervening sequences. Sixteen clones of HLA-DRB promoter showed sequence variations such as substitution and insertion/deletion, and these 16 clones could be further grouped into 6 homologues with sequence homology. These data established that the melanoma cell lines studied here showed a differential susceptibility to IFN-gamma on the modulation of HLA-DR molecules, that this modulation is transcriptionally regulated, and that the difference in promoter activity by sequence variation might contribute to such a differential transcriptional regulation at the promoter level.
Base Sequence ; Gene Expression Regulation, Neoplastic/drug effects* ; HLA-DR Antigens/genetics* ; Human ; Interferon Type II/pharmacology* ; Melanoma/genetics* ; Molecular Sequence Data ; Polymerase Chain Reaction ; Promoter Regions (Genetics) ; RNA, Messenger/analysis ; Tumor Cells, Cultured

Two human malignant melanoma cell lines, Malme-3M and SK-Mel-28, were analyzed for their ability to induce the expression of intercellular adhesion molecule 1 (ICAM-1) and human leukocyte antigen (HLA)-DR molecules on their cell surfaces as well as at the transcriptional level before and after treatment with interferon (IFN)-gamma. Both cell lines demonstrated a high percentage(> 99%) of ICAM-1 expression regardless of IFN-gamma treatment. Before IFN-gamma treatment, Malme-3M cells barely expressed HLA-DR molecules (< 2%) and SK-Mel-28 cells demonstrated a relatively high percentage(> 50%) of HLA-DR expression. Both cell lines displayed elevated levels of HLA-DR expression in a time dependent manner after IFN-gamma treatment. However, these two cell lines have been shown to respond differentially to IFN-gamma. The molecular mechanism underlying such a differential behavior was investigated, and HLA-DR gene regulation was studied at the transcriptional level. Treatment with IFN-gamma led to the steady-state mRNA augmentation of the HLR-DR gene. The HLA-DRA mRNA augmentation was similar in both cell lines, whereas in Malme-3M, IFN-gamma did not augment the rate of transcription of the HLA-DRB gene as much as in SK-Mel-28. Data from this study established the fact that the melanoma cell lines displayed a differential susceptibility to IFN-gamma on the modulation of HLA-DR molecules, and this modulation was transcriptionally regulated.
Genes, MHC Class II ; HLA-DR Antigens/*metabolism ; Human ; Intercellular Adhesion Molecule-1/*metabolism ; Interferon Type II/*pharmacology ; Melanoma/*metabolism/pathology ; Support, Non-U.S. Gov't ; Transcription, Genetic ; Tumor Cells, Cultured

A case of retroperitoneal teratoma in a 37-year old woman is presented. For approximately 20 years, she suffered from a slowly growing palpable mass and discomfort and pain in the LUQ. Upper GI series revealed compression and displacement of the greater curvature of the body of the stomach, and the outline of a large LUQ. mass overlapping the left kidney. IVP demonstrated compression of the left renal pelvis and calyceal system by this large mass, and considerable amorphous calcification in the upper pole of the mass. Pre-operatively, the mass was suspected to be a dermoidcyst or teratoma or pancreatic pseudocyst. At the operation, it proved to be a large retroperitoneal tumor mass of infant-head size, and it extended to the pancrestic hilum, including the upper pole of the left kidney, with adhesion to the left mesocolon. This huge tumor mass and involved left kidney were widely removed.
Adult ; Female ; Humans ; Kidney Pelvis ; Kidney* ; Mesocolon ; Pancreatic Pseudocyst ; Stomach ; Teratoma*