2.Requirement of diagnosis and tereatment for liver diseases and improvement of laboratory technology
Chinese Journal of Laboratory Medicine 2012;35(2):126-130
There are so many patients with different liver diseases in our country that the diagnosis and treatment of liver diseases directly relate to the people's healthy level.The requirement of diagnosis and treatment to clinical laboratories can be summarized as: ( 1 ) sensitivity,which means shortening window period;(2) specificity,which means various subtypes and variant can be detected;( 3 )speed,which means finding out the pathogen as soon as possible;(4)accuracy,which means providing physicians with accurate test reports.Detecting techniques,for instances,chemiluminescence,polymerase chain reaction and gene mutational site detecting method,were applied to the diagnosis and treatment of liver disease,thus improving the degree of precision,accuracy,sensitivity,specificity and detection speed and satisfying the requirement of diagnosis and treatment maximatily.
3.Observation of Tianwang Buxin Decoction in the Treatment of Heart Yin Deficiency Type of Generalized Anxiety Disorder
Journal of Zhejiang Chinese Medical University 2014;(8):976-978
Objective] To observe the clinical effects of Tianwang Buxin decoction in the treatment of heart Yin deficiency type of Generalized Anxiety Disorder. [Methods] 63 patients with Generalized Anxiety Disorder(heart Yin deficiency type) were randomly divided into three groups: Tianwang Buxin decoction group, paroxetine group, Tianwang Buxin decoction combined paroxetine group, course of treatment for 8weeks.Contrast the scores of three groups by HAMA before and after treatment. [Results] The clinical efficacy was almost the same among the three groups without significant difference, but the decrease of HAMA scores of Tianwang Buxin decoction combined paroxetine group was obviously lower than Tianwang Buxin decoction group and paroxetine group(P<0.05), among which, TCM group and combination group of TCM and WM had less side effect than WM group. [Conclusion]The clinical efficacy of Tianwang Buxin decoction group is almost the same with the paroxetine group without significant difference. The clinical efficacy of Tianwang Buxin decoction combined paroxetine group is more significant.
4.Diagnostic value of sonohysterography in patients with uterine cavity diseases.
Suping HAN ; Jiaying LIU ; Yundong MAO
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To evaluate the diagnostic value of sonohysterography (SHG)in uterine cavity diseases. Methods 48 patients suspected to suffer from uterine cavity diseases on the basis of transvaginal sonography underwent sonohysterography,hysteroscopy and biopsy.The results of sonohysterography were compared with those from hysteroscopy and biopsy. Results The diagnostic accuracy,sensitivity,specificity of SHG in detecting abnormal uterine cavities were 93.8%(45/48),91.4%(32/35),100%(13/13) and respectively. Conclusions SHG is a simple,effective and cheap method in the detectiou of uterine cavity diseases.
5.Association of serum resistin levels with the severity of coronary artery lesions in postmenopausal women
Tumur ODGEREL ; Jiangli HAN ; Jieming MAO
Chinese Journal of Interventional Cardiology 1996;0(01):-
Objective To examine the association between serum resistin levels and the severity of coronary artery lesions and cardiovascular risk factors in postmenopausal women.Methods The study population consisted of 117 postmenopausal women who underwent diagnostic coronary angiography for evaluation for suspected myocardial ischemia.Fasting serum resistin,insulin,blood glucose(BG),high-sensitive C-reactive protein(hs-CRP),fibrinogen(Fib)and lipid profile,including total cholesterol(TC),triglycerides(TG),HDL-cholesterol(HDL-C),LDL-cholesterol(LDL-C),apolipoprotein A1(Apo A1),apolipoprotein B(Apo B)and lipoprotein(a)(Lp(a))were measured in all the patients.Patients were divided into four groups according to the score of their coronary artery lesions:group Ⅰ included patients with coronary artery lesion score 0(no evidence of CAD),while group Ⅱ with score 1(mild lesion),group Ⅲ with score 2(moderate lesion),and group Ⅳ with score 3(severe lesion).Only patients with moderate to severe coronary lesions were diagnosed as coronary artery disease(CAD).Results Among the 117 patients,74 were diagnosed as CAD patients.Patients with CAD had significantly higher levels of resistin compared with controls:[4(1-10)?g/L vs 2(0-4)?g/L,median(interquartile range),P=0.002].In multiple logistic regression analysis,resistin levels were associated with CAD independent of age,BMI,metabolic syndrome,history of hypertension(HTN),diabetes(DM),dyslipidemia,smoking,SBP,DBP,hs-CRP,lipids [TC,TG,HDL-C,Apo A1,Apo B,Lp(a)],Fib,BG and insulin(OR 1.131,95%CI 1.012-1.263,P=0.030).Resistin levels correlated positively with CAD lesion severity in postmenopausal women(r=0.231,P
6.Effects of Electromyography Biofeedback on Dystonia after Hepatolenticular Degeneration
Yongsheng HAN ; Yuqiang MAO ; Yongzhu HAN ; Qinfan LI ; Kai LI
Chinese Journal of Rehabilitation Theory and Practice 2011;17(7):646-649
Objective To study the clinical efficacy of electromyography biofeedback on dystonia after hepatolenticular degeneration.Methods 40 patients with dystonia after hepatolenticular degeneration were divided into treatment group (n=20) and control group (n=20).All patients were treated with copper-cleaning, clonazepam and benzhexol hydrochloride etc., and acupuncture. The treatment group wastreated with electromyographic biofeedback in addition. They were assessed with modified Ashworth scale, modified Barthel index, and ankledorsiflexion active range of motion. Results The lower extremities function of all patients improved after treatment (P<0.05) and thetreatment group improved more than the control group (P<0.05). Conclusion Electromyography biofeedback is more effective to improvethe lower extremities function and activity of daily living in patients with hepatolenticular degeneration following dystonia.
7.Clinical efficacy of Naikan cognitive therapy in the treatment of alcohol dependent patients
Qi CHANG ; Fuqiang MAO ; Jingyi CHEN ; Yonghui ZHANG ; Shaoming HAN
Chinese Journal of Behavioral Medicine and Brain Science 2013;(1):25-27
Objective To explore the clinical efficacy of Naikan cognitive therapy(NCT) for alcohol dependent patients.Methods 64 cases of alcohol-dependent patients were randomly assigned to the study group (32 cases) and the control group (32 cases).The study group was treated with NCT for successive 7 days on the basis of taking original drugs; and the control group was only given the original drug therapy.The obsessive compulsive drinking scale (OCDS),self-report symptom inventory(SCL-90),nurses observation scale for inpatient evaluation(NOSIE) were administered to all subjects at pre-and post-treatment.Results ①After the treatments,the scores of OCDS in study group (49.51 ± 1.63) were lower than that in control group(53.92 ± 1.82),and the statistical difference had the significance (P < 0.01).②After the treatments,the total scores and some factor scores of SCL-90 in study group were lower than in control group (t =-2.413,P =0.019 ; t =-2.033,P =0.047 ; t =-2.065,P =0.044 ; t =-2.038,0.046),and the difference was statistically significant.③After the treatments,in the study group,the scores of the total estimated factor and total positive factor(187.10 ± 18.80;78.51 ±12.22) were higher than in control group (175.51 ± 11.71 ; 68.22 ± 11.87),total negative factor score (15.55 ±9.46) were lower than in control group (20.51 ± 9.33),and the difference was statistically significant.Conclusion NCT can effectively inhibit alcohol craving,and reduce the drinking wine relevant questions.It can help to improve psychological symptoms in patients with alcohol dependence,especially depression and anxious symptoms.
8.Clinical treatment of iatrogenic peripheral nerve injury
Xinguang HAN ; Zhenggang BI ; Lifei MAO ; Liang LEI ; Jian SHANG
Chinese Journal of Trauma 2012;28(2):125-127
ObjectiveTo retrospectively analyze the clinical outcome of patients with iatrogenic peripheral nerve injury so as to summarize the experiences and lessons.MethodsA retrospective study was performed on 72 patients with iatrogenic peripheral nerve injury treated in our hospital from 2004 to 2010.Therapy methods included conservative treatment in 24 patients,surgical release in 21 and nerve anastomosis in 27.Results All the patients were followed up for average 10 months ( range,3-24months).The neurological recovery was excellent in 24 patients,good in 21,fair in 16 and poor in 11,with excellent rate of 64%,according to the trial standard of upper limb functional assessment established by Chinese Medical Society of Hand Surgery.ConclusionsRisk awareness should be strengthened on the iatrogenic peripheral nerve injury,especially the minimally invasive treatment of fractures in recent years,which has increased the risk of nerve injury.For patients who may be presented with iatrogenic injury,we should develop a detailed preoperative surgical plan for early one stage treatment as possible.
9.Effect of Shengmai Powder on endothelin and tumor necrosis factor in hemorrhagic shock in rabbits
Jinjun MAO ; Jincheng ZHAO ; Yuze HAN ; Huaijing LI ; Yongyi LI ;
Chinese Traditional Patent Medicine 1992;0(05):-
AIM:To investigate the role of Shengmai Powder (Radix Ginseng, Radix Ophiopogonis and Fructus schisandrae) (SMP) in treatmen of hemorrhagic shock in rabbits. METHODS: The concentrations of endothelin (ET), tumor necrosis factor (TNF), ? endorphin (? EP) and nitric oxide (NO), the activity of nitric oxide synthase (NOS) in plasma were respectively tested by different biochemical assays in hemorrhagic shock in rabbits. RESULTS: SMP could obviously decrease the ET,TNF,NO level and NOS activity ( P
10.Effects of thinned cap uncovering technique on treatment for thoracic ossification of ligamentum flavum
Weigong ZHAO ; Genwen MAO ; Xuezhe HAN ; Shuming LI ; Yimin YANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2016;(2):170-173
Objective To summarize the outcome of treatment for thoracic vertebra ossification of ligamentum flavum (OLF)with en-bloc removal of the spinal canal’s posterior wall termed as the “thinned cap uncovering”technique.Methods From 2003 to 2013,56 patients with OLF were treated with thinned cap uncovering technique.In this group,there were 40 male patients and 1 6 female ones,with the average age of 45 years (range of 30-65 years)and the average history of 3 years.The 56 patients were followed up for an average duration of 2 years and 7 months (1-5 years).Results According to WANG’s evaluation,45 cases (about 80%) had excellent results,9 cases (about 1 6%)had good results,and 3 cases had improved symptoms,the excellence to good rates being 96%.Conclusion Removal of the posterior wall of the spinal canal via “thinned cap uncovering”technique is a reliable and effective treatment for thoracic OLF.The strategy for successful operation is to use high speed drill to cut bone accurately,which allows discectomy for thoracic vertebra and to diminish faults and complications during the surgical procedure.