We report a case of recurrent herpes genitalis in a 5-year-old girl which was considered to result from childhood sexual abuse. The skin lesion was an eroded erythematous macule with overlying multiple vesicles on the labia majora. We detected Herpes simplex virus DNA by using the polymerase chain reaction (PCR) in a biopsy specimen from the vesicular lesion.
Biopsy ; Child, Preschool ; Cytochrome P-450 CYP1A1 ; DNA ; Female ; Herpes Genitalis* ; Humans ; Polymerase Chain Reaction ; Sex Offenses* ; Simplexvirus ; Skin

We report a case of recurrent herpes genitalis in a 5-year-old girl which was considered to result from childhood sexual abuse. The skin lesion was an eroded erythematous macule with overlying multiple vesicles on the labia majora. We detected Herpes simplex virus DNA by using the polymerase chain reaction (PCR) in a biopsy specimen from the vesicular lesion.
Biopsy ; Child, Preschool ; Cytochrome P-450 CYP1A1 ; DNA ; Female ; Herpes Genitalis* ; Humans ; Polymerase Chain Reaction ; Sex Offenses* ; Simplexvirus ; Skin

BACKGROUND: In recent studies, tacrolimus ointment has been shown to be effective for the treatment of atopic dermatitis with an excellent safety profile. OBJECTIVE: This study was done to assess the efficacy and side-effects of tacrolimus ointment for the facial atopic dermatitis(AD) in Korean. PATIENTS AND METHODS: Open-label, non-comparative study with 2 months' follow-up was done to assess the efficacy and safety of tacrolimus ointment (Protopic0ointment 0.1%, Fujisawa, Japan) in moderate to severe facial AD. Patients were instructed to apply it two times daily for 8 weeks. Facial lesions were evaluated at baseline, 4 and 8 weeks of treatment with in-tensity score by investigator. RESULTS: In comparing of intensity scores and each clinical score at baseline with those of 4 and 8 weeks of treatment, a significant decrease was noticed at all follow-up periods. Burning sense(54.5%) and pruritus(18.2%) were detected. CONCLUSION: Tacrolimus ointment is effective in treatment of severe facial AD and has tolerable mild adverse effects at the site of application in Korean.
Burns ; Dermatitis, Atopic* ; Follow-Up Studies ; Humans ; Research Personnel ; Tacrolimus*

5 bed sand filter, applying biological oxidation, was designed and studied on the treatment of water works. Never using any coagulant agent (drugs), which may cause water pollution in pre-treatment of head water, the author attempt a high rate filtration by the microorganism (nitrofication bacteria) end plant which populate in multi layer sand beds. The result are as follows ; In order to evaluate the oxygen effect on filtration, oxygen was injected in aeration tank attached to each filter tank while filtration, and NH3 was tested as a representative ingredient. It was found out that the aeration method was more effective, with over 33% of NH3 removal capacity, than the anerobic and this 5 bed filter showed double removal capacity of NH3 by comparing with conventional sand bed (2 stage bed). According to the examination of two kind of head water, pre-treated with coagulant agent and activated carben, the filtration capacity was affected by the polluted condition of head water, resulting that lower value of pollution and slower velocity of filtration showed more efficiency of NH3 removal. In this experiment NH3 content tested in treated water had a fairly good correlation with others.
Filtration ; Head ; Oxygen ; Plants ; Silicon Dioxide ; Water Pollution ; Water*

5 bed sand filter, applying biological oxidation, was designed and studied on the treatment of water works. Never using any coagulant agent (drugs), which may cause water pollution in pre-treatment of head water, the author attempt a high rate filtration by the microorganism (nitrofication bacteria) end plant which populate in multi layer sand beds. The result are as follows ; In order to evaluate the oxygen effect on filtration, oxygen was injected in aeration tank attached to each filter tank while filtration, and NH3 was tested as a representative ingredient. It was found out that the aeration method was more effective, with over 33% of NH3 removal capacity, than the anerobic and this 5 bed filter showed double removal capacity of NH3 by comparing with conventional sand bed (2 stage bed). According to the examination of two kind of head water, pre-treated with coagulant agent and activated carben, the filtration capacity was affected by the polluted condition of head water, resulting that lower value of pollution and slower velocity of filtration showed more efficiency of NH3 removal. In this experiment NH3 content tested in treated water had a fairly good correlation with others.
Filtration ; Head ; Oxygen ; Plants ; Silicon Dioxide ; Water Pollution ; Water*

The mortality and morbidity of peritrochanteric fractures in the elderly are great due to preexisting diseases, the osteoporosis, and poor general conditions. Since the complications sometimes lead to death, it is utmost important to reduce the complications and to prevent them. Authors had experienced 42 peritrochanteric fractures over 65 years old from January, 1988 to December, 1992. Age incidence was distributed from 65 to 93 years. The sites of fractures were 17 femoral neck, 24 intertrochanteric, 1 subtrochanteric. The mortality at postoperative 6 months was 10.2%. The postoperative complications were 6 cardiovascular diseases, 3 pneunonia, 3 pressure sore etc. The results according to interval between injury and operation were not significant, but reducing risk factors following check-up of general conditions was significant. It was necessary in treatment of elderly peritrochanteric fractures to check the general conditions, to reduce risk factors, to choose appropriate method of operation and anesthesia, and to operate as soon as possible by experienced surgeon. Postoperative early ambulation was also significant at good results. The percutaneous pinning under local anesthesia was an recommendable method in patients with severely poor general conditions.
Aged ; Anesthesia ; Anesthesia, Local ; Cardiovascular Diseases ; Early Ambulation ; Femur Neck ; Humans ; Incidence ; Methods ; Mortality ; Osteoporosis ; Postoperative Complications ; Preexisting Condition Coverage ; Pressure Ulcer ; Risk Factors

No abstract available.
Follow-Up Studies* ; Spinal Stenosis*

BACKGROUND: Contact immunotherapy using diphenylcyclopropenone (DPCP) has been used in the treatment of alopecia and warts. DPCP seemed to be a promising agent for viral disease including molluscum contagiosum (MCI). OBJECTIVE: The purpose of this study was to evaluate the effect of DPCP immunotherapy on MC in children. METHODS: Twenty three patients with multiple lesion of MC were treated with DPCP immunotherapy. RESULTS: Twelve patients (52.2%) showed cure, and eleven patients (47.8%) showed treatment failure. No severe side effects were seen. CONCLUSION: DPCP immunotherapy may be an effective treatment in children with MC without serious side effects.
Alopecia ; Child ; Humans ; Immunotherapy* ; Molluscum Contagiosum* ; Treatment Failure ; Virus Diseases ; Warts

No abstract available.
Child* ; Humans ; Pityriasis Lichenoides* ; Pityriasis*

Thirty-nine cases of tuberculosis of the knee were treated at the Department of Orthopaedic Surgery, National Medical Center during the 10 yesrs from Jsn. 1977 to Dec. 1986. The results were as followings 1) Total cases of tuberculosis of bone and joint were 411. Among them, knee joint occupied 39 cases (9.5%) 2) Age and sex distribution were not remarkable. 3) Average duration of disease were 27 months. 4) In 56.1% of the pstients, chemotherapy wss given prior to admission. 5) Tbe main associated tuberculosis lesions were pulmonsry tuberculosis (53.9%). 6) Erythrocyte sedimentation rate was increased in 61.6%. 7) The incidence of associated running draining sinus were 25.6%, and majority of the causative microorganisrn was Staphylococcus aureus in complicated mixed infection. 8) Various treatment, such as conservative, synovectomy, curettage, and arthrodesis, had been carried out. 9) Overall recurrence rate was 9.1%.
Arthrodesis ; Blood Sedimentation ; Clinical Study ; Coinfection ; Curettage ; Drug Therapy ; Incidence ; Joints ; Knee Joint ; Knee ; Recurrence ; Running ; Sex Distribution ; Staphylococcus aureus ; Tuberculosis