1.A Case of Eccrine-Pilar Angiomatous Hamartoma Showing an Unusual Clinical Manifestation.
Kyu Han KIM ; Hyang Joon PARK ; Yoo Shin LEE
Korean Journal of Dermatology 1984;22(5):549-552
No abstract available.
Hamartoma*
2.The effect of adjuvant CMF(cyclophosphamide, methotrexate, 5-FU) chemotherapy of breast cancer.
Joon PARK ; Jung Han YOON ; Young Jong JEGAL
Journal of the Korean Cancer Association 1993;25(6):928-934
No abstract available.
Breast Neoplasms*
;
Breast*
;
Drug Therapy*
;
Methotrexate*
3.Red Blood Cell Indices, Serum Iron and Total Iron Binding Capacity in Children with Helicobacter pylori Infection.
Soo Joon PARK ; Chang Han LEE ; Ki Sup CHUNG
Journal of the Korean Pediatric Society 2000;43(6):755-762
PURPOSE: H. pylori infection was recently reported to be associated with unexplained iron-deficiency anemia(IDA) in children and adolescents. H. pylori-related IDA was thought to occur due to GI blood loss, scavenging of iron by H. pylori and iron malabsorption. The aim of this study was to examine how the status of H. pylori infection and age of children affected RBC indices, serum iron level and TIBC. METHODS: We performed esophagogastroduodenoscopy, and examined RBC indices, serum iron and TIBC on 178 pediatric patients with recurrent abdominal pain. H. pylori infection was assessed by CLO test and silver stain of gastric biopsy specimen. RESULTS: H. pylori infection was found in 42 of 178 patients(23.6%). In children with H. pylori infection, the prevalence of iron deficiency(ID) and IDA(39.0% and 10.3%, respectively) was higher than in children without H. pylori infection(29.6% and 4.1%, respectively), but there was no statistically significant difference. Serum iron level was lower(69.5+/-32.7 vs 77.3+/-34.1g/dL; P= 0.08) and TIBC was higher(380.8+/-50.4 vs 366.9+/-47.0g/dL; P=0.09) in children with H. pylori infection than in children without H. pylori infection. All RBC indices and iron saturation were lower in children with H. pylori infection than in children without H. pylori infection, but there was no significant difference between the two groups. In correlation analysis, serum iron, Hgb, Hct, MCV and MCH were significantly increased by age in children without H. pylori infection (P<0.05), but MCH and MCHC were decreased significantly(P<0.05) by age in children with H. pylori infection. In multiple regression analysis, the change of serum iron, MCH and MCHC by age was significantly influenced by the status of H. pylori infection(P<0.05). CONCLUSION: H. pylori infection decreases RBC indices and serum iron and increases TIBC in children. These changes become prominent as age increases. This age effect rnay be related to the duration of H. pylori infection. (J Korean Pediatr Soc 2000;43:755-762)
Abdominal Pain
;
Adolescent
;
Anemia, Iron-Deficiency
;
Biopsy
;
Child*
;
Endoscopy, Digestive System
;
Erythrocytes*
;
Helicobacter pylori*
;
Helicobacter*
;
Humans
;
Iron*
;
Prevalence
;
Silver
4.The effects of long-term lithium treatment on the parathyroid hormone and calcium level.
In Joon PARK ; Seung Hyun KIM ; Sun Ho HAN
Journal of Korean Neuropsychiatric Association 1991;30(6):974-981
No abstract available.
Calcium*
;
Lithium*
;
Parathyroid Hormone*
5.Mirizzi syndrome: one case report
Joon Koo HAN ; Byung Ihn CHOI ; Yong Hyun PARK
Journal of the Korean Radiological Society 1984;20(2):335-338
Mirizzi syndrom is a rare disorder characterized by obstruction of common hepatic duct due to impacted gallbladder neck or dystic duct stone and is an uncommon cause of obstructive jaundice. Authors experienced one case of Mirizzi syndrome mimicked lobulated intraductal tumor.
Gallbladder
;
Hepatic Duct, Common
;
Jaundice, Obstructive
;
Mirizzi Syndrome
;
Neck
6.The Relation of Antipsychotic Drug Induced-Acute Dystonia and Serum Iron Level.
Dong Jin LEE ; In Joon PARK ; Young Joon KWON ; Hee Yeon JEONG ; Sun Ho HAN
Journal of the Korean Society of Biological Psychiatry 1998;5(2):248-252
OBJECT: This study was performed in order to examine the correlation between acute neuroleptic-induced dystonic reactions and serum iron level. METHOD: Serum iron levels were measured in psychiatric inpatients who had developed acute neuroleptic-induced dystonia(N=41) and in control patients with no history of acute dystonic reactions(N=37). Serum iron levels were compared in acute dystonic inpatients before starting treatment with neuroleptics and after acute dystonic reaction. RESULTS: The patients exhibiting acute dystonic reactions had significantly lower serum iron levels than the patients without acute dystonic reactions. CONCLUSION: This result supports an association between low serum iron and the occurrence of neuroleptic-induced acute dystonic reactions.
Antipsychotic Agents
;
Dystonia*
;
Humans
;
Inpatients
;
Iron*
7.Effects of the Sanjoin on the Rat Brain: Focused on Serotonin, Sleeping Time, Sleep EEG and Autonomic Activity.
Hee Yeon JEONG ; Young Joon KWON ; In Joon PARK ; Joon Taek KWON ; Byung Hoon HAN ; Sung Pil LEE
Journal of the Korean Society of Biological Psychiatry 1997;4(1):54-59
OBJECTS: Sanjoin, the seeds of Zizyphus vulgaris var. spinosus has been used as the most important hypnotic agent in chinese medicine to treat insomnia. This research was performed in order to examine the effect of betulinic acid and sanjoinine-A which are components of Sanjoin. METHOD: Sleeping time, sleep recordings of EEG, serum serotonin level, and locomotor activity were measured in rats which received betulinic acid and sanjoinine-A as sleep induction material extracted from Sanjoin. RESULTS: 1) Groups received betulinic acid, sanjoinine-A, and lorazepam showed increased sleep time than control group with saline. 2) Groups with betulinic acid, sanjoinine-A, lorazepam and saline recorded beta-wave in sleep recording of EEG. In there was no significant difference among all groups. 3) No significant difference in serum serotonin level among all groups was found. 4) In autonomic activity testing, groups of betulinic acid, sanjoinine-A, and lorazepam showed significantly more decreased in activity than saline group. In comparison of groups of betulinic acid and sanjoinine-A with a group of lorazepam, there was no significant difference. CONCLUSION: These results suggests that betulinic acid and sanjoinine-A have the sedative effect like lorazepam rather than sleep effect.
Animals
;
Asian Continental Ancestry Group
;
Brain*
;
Electroencephalography*
;
Humans
;
Hypnotics and Sedatives
;
Lorazepam
;
Motor Activity
;
Rats*
;
Serotonin*
;
Sleep Initiation and Maintenance Disorders
;
Ziziphus
8.Relationship of Estrogen to Extrapyramidal Symptoms in Female Schizophrenic Patients.
Dong Seon CHUNG ; Hee Yeon JUNG ; Young Joon KWON ; In Joon PARK ; Sun Ho HAN ; Han Yong JUNG
Journal of the Korean Society of Biological Psychiatry 2001;8(1):147-152
OBJECTIVE: It has been thought that estrogen has neuroleptic like effect in women schizophrenic patients. This study aimed to investigate neuroleptic side-effects severity in women with schizohrenia and to investigate their putative association with variations in sex steroids over menstrual cycle. Based on the estrogen theory, The author hypothesized that parkinsonian side-effects would be exacerbated when estrogen levels were high. METHOD: 26 schizophrenic women were assessed using the ESRS(Extrapyramidal Symptom Rating Scale) and estrogen analysis. Tests were conducted twice, in the mid luteal and mid follicular phase. RESULT: It was hypothesized that high level of estrogen would lead to an exacerbation of parkisonian side-effects but the results indicated that parkinsonian side effects decreased overall when estrogen levels were high. This effects were more marked for the group taking typical neuroleptics than those taking atypical neuroleptics. CONCLUSION: The results of this study suggest that estrogen and progesteron may reduce the severity of neuroleptic indeced extrapyramidal side effects over menstrual cycle in women with schizophrenia. It was concluded that estrogen has different effects on dopamine dynamics in the mesolimbic and mesostriatal pathways according to estrogen, progesteron, catecol estrogen, prolactine.
Antipsychotic Agents
;
Dopamine
;
Estrogens*
;
Female*
;
Follicular Phase
;
Humans
;
Menstrual Cycle
;
Prolactin
;
Schizophrenia
;
Steroids
9.Selective arterial thrombolysis with urokinase.
Jae Hyung PARK ; Kil Sun PARK ; Jin Wook CHUNG ; Joon Koo HAN ; Dae Young KIM ; Sang Joon KIM
Journal of the Korean Radiological Society 1991;27(4):441-446
No abstract available.
Urokinase-Type Plasminogen Activator*
10.An experimental study on the influence of the intravasculargianturco tupe stents on the vascular structures.
Yeon Hyeon CHOE ; Jae Hyung PARK ; Joon Koo HAN ; Man Chung HAN ; Chu Wan KIM
Journal of the Korean Radiological Society 1991;27(4):431-439
No abstract available.
Stents*