No abstract available.
Prostatectomy*

PURPOSE: It is agreed that tumor stage is the definitive prognostic indicator for patients with renal cell carcinoma. We investigated pathologic grade and cell subtype as another prognostic in each tumor stage. MATERIALS AND METHODS: We reviewed the medical records of 206 patients who underwent partial or radical nephrectomy for renal cell carcinoma between January 1991 and June 1998. Renal cell carcinoma grade, stage and cell subtype (conventional [clear cell], papillary, chromophobe, sarcomatoid type) were evaluated using the 1997 Union International Contre Ie cancer (UICC) and the American Joint Committee on Cancer (AJCC) grading, TNM staging criteria and renal cell carcinoma classification. Kaplan -Meier survival curves were used to determine 5-year survival for all patient groups. Univariate analysis using log rank test was performed to evaluate the prognostic significance of TNM stage, Fuhrman nuclear grade, cell subtype and tumor size. We investigated pathologic grade and cell subtype with log rank teat whether those were another significant prognostic factors in each tumor stage. Multivariate analysis was performed to determine which factors had an independent impact on survival of patients with renal cell carcinoma. RESULTS: Univariate analysis revealed that TNM stage (p<0.001), pathologic grad (p<0.001) were the important prognostic indicators for renal cell carcinoma. Survival was affected significantly by tumor size when cutoff diameter for localized T1 lesions was 7cm but not 2.5cm. Pathologic grade had a significant impact on patient survival (p<0.0001). In the cell subtype chromophobe type had the best survival and sarcomatoid type had the worst survival though cell subtype did not appear to affect survival significantly (p=0.0583). Multivariate analysis revealed that N classification (p=0.009) and M classification (p=0.018) were the most important prognostic indicators for cell subtype (p=0.841) were not shown to have any independent impact on patient survival. In the group of localized disease(TXN0M0 stage) at the diagnosis, cell subtype had a significant impact on survival in T1(p<0.001), T2(p=0.01) and T3(p=0.029) and grade in T1(p=0.0016) and T3(p=0.0054). CONCLUSIONS: Pathologic grade and cell subtype were significant predictors of survival in each T stage of localized disease though they didn't have independent impact on the patient survival.
Carcinoma, Renal Cell* ; Classification* ; Diagnosis ; Humans ; Joints ; Medical Records ; Multivariate Analysis ; Neoplasm Staging ; Nephrectomy

No abstract available.
Magnetic Resonance Imaging* ; Prostate* ; Prostatic Neoplasms*

Santonin-kainic acid complex was evaluated as a chemotherapeutic of the mass treatment of the Ascaris lumbricoides infection in Korea. The results could be summarized as follows: The negative conversion rate was 82.9% in average in 4 treated groups. Some variations of negative conversion rate among the treated groups were noticed. The egg reduciton rate was 97.7% in average and the results were rather uniform among the three evaluated groups. By the analysis of egg reduction, it seems that the lightly infected cases whose E.P.G. were under 5,000 were resistant to treatment with the less reduced egg output. After the treatment with this complex, the number of egg discharged cases were reduced to 1.84% and the average number of discharge eggs per incompletely treated or untreated cases were reduced to 12.5% compared with the level of before-treatment egg output. The successive observations of the pattern of worm expulsion after drug intake was made. The worms were mostly expelled in the stool within 3 days, and 58.9% of total expelled worms were collected within 24-hour stool. The minimum length of the immature worms expelled was 7.6cm. Among the 659 Ascaris collected in the first-day stool from 91 rural people, 8.5% were in the range of 7.6-12.2 cm-long, immature worms. The sex ratio, male: female= 0.69: 1.
parasitology-helminth-nematoda ; Ascaris lumbricoides ; chemotherapy ; Santonin ; kainic acid

We report on a patient with spontaneous rupture of hemorrhagic renal cyst into the pyelocaliceal system. He had no history of trauma, bleeding disorders, urinary tract infection or urinary tract obstruction. Gross hematuria followed by left flank pain occurred 1 day prior to admission. Although radiologic findings were suggestive of rupture of renal cyst into the calyx or calyceal diverticulum. exclusion of malignant disease or renal carbuncle was difficult. He was managed by partial nephrectomy. Microscopic findings revealed ruptured cyst lined with low cuboidal epithelium without evidence of malignancy.
Carbuncle ; Diverticulum ; Epithelium ; Flank Pain ; Hematuria ; Hemorrhage* ; Humans ; Nephrectomy ; Rupture ; Rupture, Spontaneous* ; Urinary Tract ; Urinary Tract Infections

Extracorporeal shock wave lithotripsy was performed in 231 patients for 13 months with Dornier MPL 9000 lithotriptor. The 231 patients had renal ( 48.9%) or ureteral (51.1%) stones varying from 0.6 to 4.4cm (mean 1.2cm) in size. Among 231 patients, 184 patients (79.7%) completed the treatment with 1 session and the number of treatment sessions increased in larger stones and in situ impacted ureteral stones, with an average of 1.3 sessions. The success rate (rate free of calculi plus that of clinically insignificant residual fragments) was 98.3 %. No general or regional anesthesia was required but parental analgesics were required in 22.9% of the treatment sessions. There were no significant complications in any patient. Therefore, extracorporeal shock wave lithotripsy with Dornier MPL 9000 lithotriptor is considered to be a safe and efficient procedure for initial treatment of urinary stones.
Analgesics ; Anesthesia, Conduction ; Calculi ; Humans ; Lithotripsy ; Parents ; Shock ; Ureter ; Urinary Calculi*

Forty five patients with urinary tract infection were treated with 100mg Norfloxacin twice daily for 3 or 7 days according to the seriousness of infection. Of the 19 patients with uncomplicated urinary tract infection including 5 patients with acute bacterial prostatitis or acute epididymitis, none had bacteriuria 7 days after therapy and 1 patient was reinfected 14 days after therapy discontinuation. Of the 26 patients with complicated urinary tract infection, 17 patients(65%) were uninfected 7days after therapy and among them, 3 patients were reinfected I4 days after discontinuation of therapy. Of the 9 patients with persistent infection, 4 patients had resistant bacteriuria and 5 patients had bacteriuria different from that found before therapy. Eradication rate of E. coli, Enterobacter spp., Proteus spp., Pseudomonas spp., and Serratia spp. were 100%,, 100%,, 100%,, 80% and 40%, respectively. Further clinical envaluation seems worthwhile especially in pseudomonas infections since it offers one of the very few alternatives for oral treatment of pseudomonas infections which today may require hospitalization only for the purpose of injectible antibiotics.
Anti-Bacterial Agents ; Bacteriuria ; Enterobacter ; Epididymitis ; Hospitalization ; Humans ; Male ; Norfloxacin ; Prostatitis ; Proteus ; Pseudomonas ; Pseudomonas Infections ; Serratia ; Urinary Tract Infections* ; Urinary Tract*

Twenty two children, aged from I year to 15 years, with urinary stones have been admitted to Seoul National University Hospital from 1970 to 1983. Clinical, laboratory, radiographic and follow-up findings are described. Incidence of lower urinary stones were high, 31.8%. Stones were multiple in 14 cases, bilateral in 2 cases. Urologic lesions were associated in 4 children. Three of these were congenital, one was posttraumatic. On longitudinal looking, recurrences occurred in 5 cases. Reoperations were necessary in 3 cases. One of these was nephrectomy, 13 years after pyelolithotomy. We conclude recurrences are not low in childhood and long follow-up should be maintained.
Child ; Follow-Up Studies ; Humans ; Incidence ; Nephrectomy ; Recurrence ; Seoul ; Urinary Calculi ; Urolithiasis*

Twenty two children, aged from I year to 15 years, with urinary stones have been admitted to Seoul National University Hospital from 1970 to 1983. Clinical, laboratory, radiographic and follow-up findings are described. Incidence of lower urinary stones were high, 31.8%. Stones were multiple in 14 cases, bilateral in 2 cases. Urologic lesions were associated in 4 children. Three of these were congenital, one was posttraumatic. On longitudinal looking, recurrences occurred in 5 cases. Reoperations were necessary in 3 cases. One of these was nephrectomy, 13 years after pyelolithotomy. We conclude recurrences are not low in childhood and long follow-up should be maintained.
Child ; Follow-Up Studies ; Humans ; Incidence ; Nephrectomy ; Recurrence ; Seoul ; Urinary Calculi ; Urolithiasis*

No abstract available.
Prostate* ; Prostatectomy* ; Prostatic Neoplasms*