1.The effect of the combined estrogen progesteron therapy for 2 years on bone mineral density in postmenopausal women.
Yong Ki MIN ; Hak Chul JANG ; Chee Jeong KIM ; In Kwon HAN
Journal of Korean Society of Endocrinology 1991;6(3):222-226
No abstract available.
Bone Density*
;
Estrogens*
;
Female
;
Humans
2.Computed tomographic evaluation of cerebral disorder in pediatric population
Jang Sik LEE ; Sang Il SUH ; Jeong Dong JEON ; Chang Yul HAN ; Soo Sung PARK
Journal of the Korean Radiological Society 1983;19(4):681-687
A total of 110 computed tomographic scans of the brain in pediatric population were reviewed. They wereretrospectively analyzed focusing on the ventricular dilatation, widening of subdural space in frontal region andprominence of cerebral sulci in hemisphere. The results were compared with clinical recored. In the measurementbicaudate ventricular index waas above 0.18, which ws considered ventricular dilatation. The subdural space in thefrontal region and teh prominent cerbral sulci in the hemisphere were visualized among the cases aged over twoyears with clinical evidence of cerbral problem is pediatric population. The diagnostic application of CT to thecases of cerebral disorder in pediatric population is highly recommended.
Brain
;
Dilatation
;
Subdural Space
3.The Role of Histone Acetylation in Mesenchymal Stem Cell Differentiation
Sujeong JANG ; Jinsu HWANG ; Han-Seong JEONG
Chonnam Medical Journal 2022;58(1):6-12
The mechanism and action concerning epigenetic modifications, especially that of histone modifications, are not fully understood. However, it is clear that histone modifications play an essential role in several biological processes that are involved in cell proliferation and differentiation. In this article, we focused on how histone acetylation may result in differentiation into mesenchymal stem cells as well as histone acetylation function. Moreover, histone acetylation followed by the action of histone deacetylase inhibitors, which can result in the differentiation of stem cells into other types of cells such as adipocytes, chondrocytes, osteocytes, neurons, and other lineages, were also reviewed.
4.Analysis of Experimental Researches in Korea on the Effects of Aromatherapy to Relieve Pain.
Jeong Sook PARK ; Jeong Eon PARK ; Jang Soon YANG ; Hye Weon KWAK ; Jung An HAN
Korean Journal of Hospice and Palliative Care 2011;14(1):8-19
PURPOSE: This study identifies research trends and provides fundamental data related to curative power of aromatherapy to relieve pain in Korea. METHODS: The study analyzed 44 experimental studies on humans that were published in Korea before the end of December, 2009. The key words used for searching were: aroma, aromatherapy, hyang-yobeob, hyanggi-yobeob, hyanggichilyo, aromatherapy and pain, headache, scapulodynia, omodynia, feeling uncomfortable in the perineal region, sense of pain, labor pains, arm pain, menstrual pain, aches, and dysmenorrheal. Those words were found on websites, including those for Korea Education & Research Information Service, the National Assembly Library, KISS, KoreaMed, and NDSL. Collected data were analyzed using descriptive statistics. RESULTS: The results showed that most of essential oils to relieve pain is composed of three to four kinds of oils, including Lavender, Roman chamomile, Rosemary, and Clarysage. Aromatherapy is applied usually by means of massage (50%), inhalation (13.6%), or a combination of the above two (13.6%). Measuring instruments as a dependent variable include VAS, questionnaire, GRS, blood pressure, pulse, and Algometer. Aromatherapy plays an important role in soothing headaches and arthralgia. However, when it comes to labor and menstrual pain, it doesn't seem to be effective. CONCLUSION: The study found that different kinds of oil, frequencies, and periods of time are used for the same symptoms. Further research should employ standardized oil blending, application, duration, and measuring instruments, and more systematically analyze the effects of aromatherapy to establish the effects on relieving pain.
Arm
;
Aromatherapy
;
Arthralgia
;
Blood Pressure
;
Chamaemelum
;
Dysmenorrhea
;
Female
;
Headache
;
Humans
;
Information Services
;
Inhalation
;
Korea
;
Labor Pain
;
Lavandula
;
Massage
;
Oils
;
Oils, Volatile
;
Pregnancy
;
Surveys and Questionnaires
5.The relationship to alpha-fetoprotein and immunoglobulin levels in maternal and fetal serum, and birth weight.
Gong Chang HAN ; Ha Jong JANG ; Jong Il JUNG ; Se Joon HAN ; Hyuck JEONG ; Se Ryang OH
Korean Journal of Obstetrics and Gynecology 1991;34(8):1085-1089
No abstract available.
alpha-Fetoproteins*
;
Birth Weight*
;
Immunoglobulins*
;
Parturition*
6.Factors Affecting Activities of Daily Living in Severely Disabled Stroke Patients.
Hyewon JEONG ; Soo Jeong HAN ; Soon Ja JANG ; Jeong Eun LEE
Brain & Neurorehabilitation 2018;11(2):e11-
To investigate factors which affect the activities of daily living (ADL) in severely disabled stroke patients. Medical records of 64 post-stroke patients were reviewed retrospectively. All patients had had rehabilitation for 3 months, and their ADL was assessed using the Korean version of Modified Barthel Index at the time of admission and after 3 months. We also investigated age, onset duration of stroke and the Korean version of Mini-Mental State Examination (K-MMSE) at the time of admission. The ability to roll over, sit, sit to stand, transfer, ambulation, climbing stairs, sitting balance and standing balance were evaluated at the time of admission and after 3 months, either. The factors affecting ADL were K-MMSE and functional ability, such as the ability to roll over, come to sit, sit to stand, sitting and standing balance. The most important factors were the level of K-MMSE and the ability to come to sit. The ability to sit up and the K-MMSE score are the independent factors that can predict the ADL after rehabilitation in severely disabled stroke patient.
Activities of Daily Living*
;
Humans
;
Medical Records
;
Recovery of Function
;
Rehabilitation
;
Retrospective Studies
;
Stroke*
;
Treatment Outcome
;
Walking
7.Detection of JC Virus T-Ag in Early Gastric Cancer.
Eun Jeong JANG ; Jung Sik JANG ; Jae Hoon KIM ; Han Ik BAE ; In Soo SUH
Korean Journal of Pathology 2010;44(5):456-461
BACKGROUND: JC virus (JCV) is a polyomavirus that commonly infects humans and can cause progressive multifocal leukoencephalopathy in immunocompromised patients. Recently, many reports have documented detection of JCV in gastrointestinal tract cancers. We investigated the presence of JCV in gastric adenocarcinoma, adenoma, and non-neoplastic gastric mucosa. METHODS: We selected paraffin-embedded tissue from endoscopic mucosal resections performed from January 2007 to September 2008. DNA was extracted from the paraffin-embedded specimens of 30 adenocarcinomas, 20 adenomas of the stomach, and 20 non-neoplastic gastric mucosa. Polymerase chain reaction amplifications were performed using gene-specific primers to detect the JCV gene sequences, and immunohistochemical staining was performed to detect the T-antigen (T-Ag) protein. RESULTS: The T-Ag sequence was detected in nine of 30 gastric cancers (30%), two of 20 adenomas (10%), and eight of 20 non-neoplastic gastric mucosa specimens (40%). T-Ag protein expression was found in five of 30 gastric cancers (16.7%) and one of 20 non-neoplastic gastric mucosa specimens (5%), whereas no expression was observed in any of the adenomas. CONCLUSIONS: Although we could not detect a correlation between JCV and gastric cancer, we demonstrated the presence of JCV T-Ag expression in human gastric cancers. These findings suggest a possible role for JCV in gastric carcinogenesis.
Adenocarcinoma
;
Adenoma
;
Antigens, Viral, Tumor
;
DNA
;
Gastric Mucosa
;
Gastrointestinal Neoplasms
;
Humans
;
Immunocompromised Host
;
JC Virus
;
Leukoencephalopathy, Progressive Multifocal
;
Polymerase Chain Reaction
;
Polyomavirus
;
Stomach
;
Stomach Neoplasms
8.Relationship Between Facial Bone Fractures and the Risk of Posttraumatic Complications: A Hypothesis on the Cushion Effect of the Facial Skeletons in Temporal Bone Fractures
Hantai KIM ; Jang Gyu HAN ; Hun Yi PARK ; Yun-Hoon CHOUNG ; Jeong Hun JANG
Journal of Korean Medical Science 2023;38(27):e215-
Background:
This study investigated whether concomitant facial bone (FB) fractures reduce temporal bone (TB) injuries, such as posttraumatic facial palsy and vertigo, through an impact absorbing effect, so-called “cushion effect,” in severe trauma patients.
Methods:
A total of 134 patients with a TB fracture were included. They were divided into two groups according to their concomitant facial fractures: group I (no FB fracture) and group II (FB fracture). We compared clinical characteristics, such as brain injury, trauma severity, and complications of TB fracture, between the two groups.
Results:
In group II, immediate facial palsy was more frequent (11.6% vs. 1.5% in group I), and the Injury Severity Score was higher (19.0 ± 5.9 vs. 16.7 ± 7.3, P = 0.020). Delayed facial palsy (12.3% in group I vs. 4.3% in group II) and posttraumatic vertigo (24.6% vs.7.2%) occurred more often in group I. FB fractures significantly decreased the incidence of posttraumatic vertigo (odds ratio [OR], 0.276; 95% confidence interval [CI], 0.083–0.914). Intraventricular hemorrhage (OR, 20.958; 95% CI, 2.075–211.677), facial nerve canal injury (OR, 12.229; 95% CI, 2.465–60.670), and FB fractures (OR, 16.420; 95% CI, 1.298–207.738) increased the risk of immediate facial palsy.
Conclusion
Concomitant FB fractures reduced the risk of the occurrence of delayed facial palsy and posttraumatic vertigo in injured patients with TB fracture. Particularly, an anterior force may be reduced by the cushion effect of the bony fracture.
9.Subcutaneous Emphysema and Hypercarbia Following Laparoscopic Cholecystectomy by Increased Intraabdominal Pressure: A case report.
Jin Kyung KIM ; Sie Jeong RYU ; Se Hun PARK ; Kyung Han KIM ; Tae Ho JANG ; Se Hwan KIM
Korean Journal of Anesthesiology 1997;33(2):376-380
Subcutaneous emphysema is a complication of the pneumoperitoneum necessary to perform laparoscopy and will be seen more often as laparoscopic techniques are applied to a growing number of intraabdominal procedures. We report a case of subcutaneous emphysema and hypercarbia without pneumothorax or pneumomediastinum during laparoscopic cholecystectomy, which was treated by multiple puncture with 18G needle on emphysematous site. The suspected cause is inadvertent subcutaneous insufflation of carbon dioxide through the trocar sites by increased intra-abdominal pressure for the establishment of pneumoperitoneum. Immediate recognition, evaluation, and treatment of subcutaneous emphysema is necessary since this can be life-threatening complication.
Carbon Dioxide
;
Cholecystectomy, Laparoscopic*
;
Insufflation
;
Laparoscopy
;
Mediastinal Emphysema
;
Needles
;
Pneumoperitoneum
;
Pneumothorax
;
Punctures
;
Subcutaneous Emphysema*
;
Surgical Instruments
10.ANALYSIS OF ARTICLES PUBLISHED IN THE JOURNAL OF THE KOREAN SOCIETY OF EMERGENCY MEDICINE.
Dae Kon SHON ; Keun Jeong SONG ; Seok Joon JANG ; Han Shick LEE
Journal of the Korean Society of Emergency Medicine 1997;8(1):24-30
To raise the quality of research, medical articles which are feasible and objective must be continuously published and be continuously monitored. All articles published in the Journal of the Korean Society of Emergency Medicine from November, 1990 to November, 1995 were compared with a foreign emergency medical journal, the American Journal of Emergency Medicine(AJE). Classifying the articles in the Journal of the Korean Society of Emergency Medicine, there were 15 (8.4%) review articles, 145 (81.0%) original articles and 19 (10.6%) case reports. In the AJE, there were 103 (15.1%) review articles, 304 (44.4%) original articles and 277 (40.5%) case reports. Classifying the original articles in the Journal of the Korean Society of Emergency Medicine, there were 13 (9.0%) experimental articles, 88 (60.7%) descriptive articles and 44 (30.3%) analytic articles. In the AJE, there were 40 (13.2%) experimental articles, 59 (19.4%) descriptive articles and 205 (67.4%) analytic articles. The classification of original articles according to frequency in the Journal of the Korean Society of Emergency Medicine is trauma, resuscitation, toxicology and medical emergency, where as the AJE is medical emergency, trauma, toxicology and EMS. For statistical methods used in original articles, 90 (62.1%) case did not do any statistical analysis or where only descriptive statistics were used. In 6 (4.1%) cases the statistical level was described but statistical methods were nonmentioned. By simple classification study, there were 44 (30.3%) cases of original articles in the Journal of the Korean Society of Emergency Medicine, and 6 (2.0%) cases in the AJE. Because the development of Emergency Medicine as a special department is based on logical articles, organization of articles have study design, make hypothesis, sample gathering, statistical analysis and feasibility of conclusion. For this, the emergency training course needs a course on research methodology.
Classification
;
Emergencies*
;
Emergency Medicine*
;
Logic
;
Research Design
;
Resuscitation
;
Toxicology