1.The pulmonary artery doesn′t participate in the blood supply of lung cancer: experimental and DSA study
Mingjun HAN ; Gansheng FENG ; Jianyong YANG
Chinese Journal of Radiology 2000;0(12):-
Objective To investigate whether or not the pulmonary artery participates in the blood supply of lung cancer and its change of morphology and blood flow in lung cancer. Methods Two different colors of silicone were injected separately into the bronchial and pulmonary arteries of 33 rat models with squamous cell carcinoma of lung. The origin of blood supply of lung cancer and the morphologic change of pulmonary artery were observed under a stereomicroscope. The DSA of bronchial and pulmonary artery were performed simultaneously in 28 patients with lung cancer. Results The pulmonary branch of rat and patients were reduced, thinned and occluded in the affected lung. The pulmonary artery did not form tumor vessel, and pulmonary blood flow and perfusion were reduced or absent in the affected area. Conclusion The pulmonary artery didn′t participate in the blood supply of lung cancer. It is unreasonable to perform transcatheter chemo embolization for lung cancer via pulmonary arteriay.
2.Analysis of blood biochemistry and arterial blood gas of systemic inflammatory response syndrome in the early time after trauma
Zeqiang ZHOU ; Feng YANG ; Qing HAN
Chinese Journal of Pathophysiology 1999;0(09):-
AIM: To explore the variation of blood biochemistry and arterial blood gas of patients with systemic inflammatory response syndrome (SIRS) in the early time after trauma and improve the diagnosis and first aid. METHODS: Eighty-eight patients with trauma from August 2003 to February 2004 were divided into two groups by their AIS-ISS90 score. The data of temperature, pulse, respiratory rate, white blood cell counts, Hb, blood glucose and arterial blood gas (PaO 2, PaCO 2, HCO 3 -, AG) were collected and compared with each group by statistic methods. RESULTS: Of the 88 patients, 49 underwent SIRS, 12 in light trauma group (ISS≥16) and 37 in severe trauma group (ISS45 mmHg or 0 05). 13 patients had MODS in severe trauma group and 2 died while none had MODS or died in light trauma group. CONCLUSION: Application of AIS-ISS90 and SIRS-related blood biochemistry and arterial blood gas is beneficial for the diagnosis and treatment for patients in the early time after trauma. [
3.Effect of Yigan Granules on Bile Secretion in Rats
Jianping CHEN ; Feng HAN ; Chao HAN ; Kunwei LI ; Bin YANG
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
Objective To study the effect of Chinese Herb of Yigan Granules in different dosages on bile secretion in rats.Methods The rats were randomly divided into 5 groups: blank control group,positive control group and high,mod erate,low dosages of Yigan Granules groups.The medicines were administered thr ough duodenal intubation for the rats.Then the volume of bile were gathered by common bile duct intubations in different time,and the volume of bile and the contents of bilirubin in bile were tested before and after given drugs.Results Yigan Granules increased the bile secretion in a dose-dependent manner and promote the secretion of bilirubin.Conclusion Chinese Herb of Yigan granules has a choleretic effect.
5.Changes in serum sex hormone level and their significance in Alzheimer's disease
Hua YANG ; Qiumin QU ; Feng GUO ; Jianfeng HAN ; Chengbin WU
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
0.05). Estrogen was lower in the patients with AD than in the normal controls and there was a significant difference between the two groups (P
6.Detection on the expression of PKC-? protein in lung cancer by tissue microarray
Zhiqiang GAO ; Xiaohua YANG ; Jiuxian FENG ; Baohui HAN
China Oncology 2006;0(09):-
Background and purpose:Protein kinase C (PKC) is a potentially important target for cancer therapy due to its potential role in carcinogenesis. Abnormal expression and increasing activity of PKC-?are present in non-small cell lung cancer (NSCLC).The aim of this study is to investigate PKC-? protein expressions in lung cancer tissues by tissue microarray and their significance. Methods:Using tissue microarray, PKC-? protein expression in lung cancer patients was examined by immunohistochemistry. 182 samples of umor tissues and 18 samples of adjacent tissues were taken;of the 182 samples, 160 were NSCLC tissues and 22 were SCLC;102 samples from stage I cases and 58 from stageⅡ-Ⅲ cases.Results:Expression of PKC-? protein was observed in 48.3% (88/182) of cancerous tissues and 16.7% (3/18) of adjacent tissues (P
9.Diagnosis and treatment of acquired idiopathic laryngomalacia.
Da-zhang YANG ; Jun HAN ; Yun FENG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(6):468-469
Adult
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Aged
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Cartilage Diseases
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diagnosis
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therapy
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Humans
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Laryngeal Cartilages
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Laryngeal Diseases
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diagnosis
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therapy
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Male
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Middle Aged
10.ANALYSIS OF PHYTOSTEROLS CONTENT IN CEREALS AND LEGUMES
Junhua HAN ; Meiyuan FENG ; Guodong WANG ; Yuexin YANG
Acta Nutrimenta Sinica 2004;0(05):-
Objective: To analyze the phytosterols content in cereals and legumes commonly consumed in China, and to estimate the intake of phytosterols in Chinese people. Methods: 25 cereals and 16 legumes were chosen as samples. The content of ?-sitosterol, campesterol, stigmasterol, ?-sitostanol, campestanol were analyzed by GC methods and the total phytosterols were calculated; The intake of phytosterols in Chinese people were estimated using the data of “Survey on the Status of Nutrition and Health of the Chinese People” in 2002. Results: The content of phytosterols in wheat flour was higher than that in rice. The refinements of cereals will decrease the phytosterols content. Phytosterols content in soybean was higher than other legumes. The intake of phytosterols in Chinese people was estimated to be 130.76mg/d from cereals and 7.86mg/d from legumes. Conclusion: The analysis of phytosterols in food and the estimation of daily intake is valuable for chronic disease prevention. The higher consumption of wheat flour and legumes in diet is recommended.