1.Differences in thrombolytic effects in accordance with dosing- resimens of tissue- type plasminogen activator in experimental pulmonary embolism.
Hee Soon CHUNG ; Ho Jung KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1993;40(2):123-134
No abstract available.
Plasminogen Activators*
;
Plasminogen*
;
Pulmonary Embolism*
2.A Case of Meibomian Gland Adenocarcinoma.
Han Chol KIM ; Song Hee LEE ; Byoung Gook PAK
Journal of the Korean Ophthalmological Society 1971;12(1):35-39
The clinical resemblance of carcinoma of the Meibomian gland to the relatively frequent chaiazion should be kept in mind by anyone performing eye lid surgery. A 46-year-oId Korean house wife was first visited here in May 2nd '69 with complaints of localized swelling, ulceration and dull pain on the left upper lid. She had been taken the operation for chaiazion on the same side of the left upper eye lid a year ago. Examination revealed a reddened hard, tender lesion elevating the skin on the medial one third of the left upper lid with ulceration at its center. The tarsal conjunctiva was noted yellowish patches with ulceraion extended to its margin. Local resection with full thickness containing normal tissue around he lesion of upper lid was performed and graft was made in lower lid and rotatory transplantation was given, and pathologic examination revealed adeno-carcinoma of Meibimian gland. There was no evidence of recurrence and metastasis to remote site a year after surgery.
Adenocarcinoma*
;
Conjunctiva
;
Humans
;
Meibomian Glands*
;
Neoplasm Metastasis
;
Recurrence
;
Skin
;
Spouses
;
Transplants
;
Ulcer
3.An Experimental Study on the Role of Blood Vessels in the Formation of Peritumoral Abnormal MR Signal Intensity.
Man Chung HAN ; Heung Sik KANG ; Chu Wan KIM ; Ji Hye KIM ; Chol Woo KIM
Journal of the Korean Radiological Society 1994;31(5):933-939
PURPOSE: To assess the role of blood vessels in the formation of peritumoral abnormal signal intensity which exaggerates the size of malignant tumor on MR images. MATERIALS AND METHODS: We performed MR-microangiographic-pathologic correlation using implanted VX-2 carcinoma in 16 rabbit thighs 1-28 days after tumor implantation. The shape and distribution of abnormal vessels were analyzed on microangiography and on histologic examination in correlation with peritumoral abnormal signal intensity on MR images. RESULTS: Dilated peritumoral blood vessels gave rise to irregular, tortuous tumor vessels penetrated into the tumor. With the tumor growth, hypervascular tumor vessels in peritumoral area and central avascular areas were increased. These hypervascular areas on microangiography were corresponded with abnormal signal intensity on MR images. CONCLUSION: Hypervascularity could be a cause of peritumoral abnormal signal intensity which exaggerates the size of experimentally induced malignant musculoskeletal tumors on MR images.
Blood Vessels*
;
Thigh
4.Application of polymerase chain reaction(PCR) to the diagnosis of tuberculosis.
Ho Joong KIM ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(6):517-525
No abstract available.
Diagnosis*
;
Tuberculosis*
5.Identification of mycobacterium tuberculosis in pleural effusion by polymerase chain reaction(PCR).
Ho Joong KIM ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1993;40(5):509-518
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Pleural Effusion*
6.Diffuse reticular interstitial infiltrations accompanied by hyperinflation.
Kye Young LEE ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1993;40(1):79-83
No abstract available.
7.The effects of mycobacterium tuberculosis on alveolar macrophages.
Keon Youl KIM ; Kye Young LEE ; In Kyu HYUN ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(6):526-535
No abstract available.
Macrophages, Alveolar*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
8.Hypoxemia In Liver Cirrhosis And Intrapulmonary Shunt Determination Using Tc-99m-MAA Whole Body Scan.
Kye Young LEE ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1994;41(5):504-512
BACKGROUND: It is well known that severe hypoxemia is often associated with liver cirrhosis without preexisting cardiac or pulmonary diseases. Pulmonary vascular impairments, more specifically, intrapulmonary shunting have been considered as a major mechanism. Intrapulmonary shunting arises from pulmonary vascular dilatation at the precapillary level or direct arteriovenous communication and has relationship with the characteristic skin findings of spider angioma. However, these results are mainly from Western countries where alcoholic and primary biliary cirrhosis are dominant causes of cirrhosis. It is uncertain that tie same is true in viral hepatitiss associated liver cirrhosis, which is dominant causes of liver cirrhosis in Korea. We investigated the incidences of hypoxemia and orthodeoxia in Korean cirrhotic patients dominantly composed of postnecrotic cirrhosis and the significance of intrapulmonary shunting as the suggested mechanism of hypoxemia. METHOD: We performed the arterial blood gas analysis separately both at the supine and errect position in 48 stable cirrhotic patients without the evidences of severe complications such as ascites, variceal bleeding, and hepatic coma. According to the results of arterial blood gas analysis, all patients were divided into hypoxemic and normoxemic group. In each group, pulmonary function test and Tc-99m-MAA whole body scan were performed. The shunting fraction was calculated based on the fact that the sum of cerebral and bilateral renal blood flow is 32% of the systemic blood flow. RESULTS: The hypoxemia of PaO2 less than 80 mmHg was observed in 9 patients(18.8%) and Orthodeoxia more than 10 mmHg was observed in 8 patients(16.7%). Hut there was no patient with significant hypoxemia of PaO2 less than 60 mmHg. PaO2 was significantly decreased in the patients with spider angioma than the patients without spider angioma and showed no correlation with the serologic type and severities of liver function test findings. Any parameters of pulmonary function test did not demonstrate the difference between normoxemic and hypoxemic group. But hypoxemic group showed significantly increased shunt fraction of 11.4+/-4.1% than normoxemic group of 4.1+/-2.0% (p<0.05). CONCLUSIONS: Hypoxemia is not infrequently observed complication in liver cirrhosis and intrapulmonary shunting is suggested to play a major role in the development of hypxemia. But there was no great likelihood of clinically significant hypoxemia in our domestic cirrhotic patients predominantly composed of postnecrotic type.
Alcoholics
;
Anoxia*
;
Ascites
;
Blood Gas Analysis
;
Dilatation
;
Esophageal and Gastric Varices
;
Fibrosis
;
Hemangioma
;
Hepatic Encephalopathy
;
Humans
;
Incidence
;
Korea
;
Liver Cirrhosis*
;
Liver Cirrhosis, Biliary
;
Liver Function Tests
;
Liver*
;
Lung Diseases
;
Renal Circulation
;
Respiratory Function Tests
;
Skin
;
Spiders
;
Technetium Tc 99m Aggregated Albumin*
;
Whole Body Imaging*
9.Screening for early detection of lung cancer: results from Seoul National University Hospital.
Yong Chol HAN ; Chul Gyu YOO ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM
Tuberculosis and Respiratory Diseases 1991;38(2):119-127
No abstract available.
Lung Neoplasms*
;
Lung*
;
Mass Screening*
;
Seoul*
10.The role of pulmonary capillary pressure in the oxygen free radical- induced acute lung injury.
Chul Gyu YOO ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(6):474-483
No abstract available.
Acute Lung Injury*
;
Capillaries*
;
Oxygen*