1.Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks.
Mudasser HABIB ; Iftikhar HUSSAIN ; Hamid IRSHAD ; Zong-zhao YANG ; Jiang-bing SHUAI ; Ning CHEN
Journal of Zhejiang University. Science. B 2006;7(8):660-664
Infectious bursal disease virus (IBDV) was inactivated by two different chemicals--formaldehyde and binary ethylenimine (BEI). Formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.
Animals
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Antibodies, Viral
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blood
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Aziridines
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pharmacology
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Chickens
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Formaldehyde
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pharmacology
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Infectious bursal disease virus
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immunology
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Vaccination
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Vaccines, Inactivated
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immunology
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Viral Vaccines
;
immunology