PURPOSE: This study was performed to evaluate the efficiency of Platelet-rich plasma (PRP) for acceleration of bone healing process on allograft transplantation after curettage in benign bone tumor. MATERIALS AND METHODS: From December 2007 to February 2009, twenty-one patients who had benign bone tumor and underwent allograft transplantation after curettage were evaluated. Mean follow-up period was 14.6 months (range, 12-26 months). We compared with 13 cases of PRP group and 8 cases of non-PRP group in terms of size of lesion, bone resorption, amount of applied PRP and complications. The mean age at surgery was 23.6 years (range, 4-73 years). The most common diagnosis was simple bone cyst (7) followed by enchondroma (4), giant cell tumor (3), undifferentiated benign bone tumor (3) and so on. RESULTS: The mean size of lesion was 33.5 cm3 (range, 2.3-181.9 cm3) (29.4 cm3 in PRP group and 40.2 cm3 in non-PRP group). The mean volume of injected PRP was 7.4 cc (range, 3-12 cc). Bone union started at 3.0 months (range, 1.5-5.8 months) in PRP group and 5.3 months (range, 4-8 months) in non-PRP group. Three cases for each group were excluded due to recurrence and pathologic fracture. One patient had febrile episode 3 weeks later after surgery which subsided with antibiotics. CONCLUSION: The PRP could accelerate bone union in allograft transplantation after curettage of benign bone tumor. Furthermore, we expect that PRP can accelerate bone union in fracture or non-union.
Acceleration ; Anti-Bacterial Agents ; Bone Cysts ; Bone Resorption ; Chondroma ; Curettage ; Follow-Up Studies ; Fractures, Spontaneous ; Giant Cell Tumors ; Humans ; Platelet-Rich Plasma ; Recurrence ; Transplantation, Homologous ; Transplants

No abstract available.
Digoxigenin* ; DNA* ; Hepatitis B virus* ; Hepatitis B* ; Hepatitis*

No abstract available.
Septo-Optic Dysplasia*

PURPOSE: Periventricular leukomalacia(PVL) is associated with various neurologic sequelae such as cerebral palsy and cortical blindness. The aim of this study was to analyse the correlation between the degree of PVL on MRI and clinical features or its severity. METHODS:Thirty-eight children with PVL on MRI among children brought to Pusan National University Hospital between January 1996 and August 1999 with development delay, cerebral palsy or epilepsy were included into the study group. We reviewed medical records of the patients including the gestational age, birth weight and neurologic sequelae. The grade for PVL was divided into 1 to 3, and it was based on abnormally increased signal intensity in periventricular white matter or a reduced amount of periventricular white matter or both, and compensatory focal ventricular enlargement. We analysed the relationship of the grade of PVL and various clinical findings. RESULTS: The age ranged from 11 months to 13 years old with a mean of 42 months. History of cesarean delivery and ventilator care were significantly frequent for the severe grade of PVL. Birth weight was significantly lower according to grade of PVL. Gestational age was lower according to the grade of PVL, but was not significant statistically. Incidence of cerebral palsy was significantly higher on the severe grade of PVL. Incidence of epilepsy and mental retardation were 34.2Yo and 23.9M, not associated with the grade of PVL. CONCLUSION: Incidence of cerebral palsy was associated with the severe grade of PVL, so we think MRI can be helpful in predicting neurodevelopmental outcome. (J Korean Pediatr Soc 2000;43 798-805)
Adolescent ; Birth Weight ; Blindness, Cortical ; Brain* ; Busan ; Cerebral Palsy ; Child ; Epilepsy ; Gestational Age ; Humans ; Incidence ; Infant, Newborn ; Intellectual Disability ; Leukomalacia, Periventricular* ; Magnetic Resonance Imaging* ; Medical Records ; Ventilators, Mechanical

Roentgenograms of the chest were reviewed from 122 childrens with acute glomeruloneph ritis. Abnormalities were found in 110 roentgenograms. These included cardiomegaly in 82(67.2%), prominent pulmonary vasculature in 98(80.3%), pleural effusion in 35(28.6%), pulmonary edema in 24(19.6%), and pulmonary consolidation in 20(16.3%). The roentgen findings in the chest, although not pathognomic, may have diagnostic values occasionally.
Cardiomegaly ; Child* ; Humans ; Pleural Effusion ; Pulmonary Edema ; Thorax*

No abstract available.
Giant Lymph Node Hyperplasia* ; Neck*

For many years, interest in cardiac function has primarily centered around the systolic pump performance of the left ventricle. it is now recognized, however, that diastolic abnormalities may be just as important in the pathophysiology of certain cardiac disease states. To examine the left ventricular abnormalities (especially diastolic events) in hypertension, diastolic and systolic time intervals were measured from simultaneous high-speed recordings of a phonocardiogram, ECGs, apexcardiogram, echocardiogram and external carotid pulse in 35 hypertensive patients and were compared with those in 15 normal subjects. The hypertensive patients showed significantly prolonged preejection period (PEP) and shortened ejection time (ET), compared to those in normal control subjects (p<0.005, p<0.05 respectively). The PEP/ET ratio too was different from the control subjects in hypertensive patients (0.335+/-0.050 vs 0.422+/-0.666; p<0.005). The isovolumic relaxation time (IVRT) was increased to 81.3+/-15.0 msec, which was significantly longer (p<0.005) than in normal subjects (56.7+/-10.7 msec), in patients with hypertension. The active filling period (AFP) was also prolonged. In patients with hypertension there was no significant difference in rapid filling period and slow filling period compared with those in normal subjects. It is likely that in hypertensive patients the alterations of diastolic time intervals, reflecting disorders in elasticity and compliance, may occur in conjunction with abnormal systolic events.
Compliance ; Elasticity ; Electrocardiography ; Heart Diseases ; Heart Ventricles ; Humans ; Hypertension ; Relaxation ; Systole*

OBJECTIVES: This study aimed to figure out the characteristics and differences of therapeutic environment by classifying into closed-ward inpatient, open-ward inpatient and community residence outpatient environment and comparing objective and subjective quality of life of each group. METHODS: The subjects consisted of 67 open-ward chronic inpatients, 58 closed -ward inpatients in the National Naju Mental Hospital and 85 outpatients living in Naju. We measured objective and subjective quality of life using semi-structural interview by Leman's quality of life scale and compared the 3 groups. We used one-way ANOVA and chi-square test to analyze the differences of the 3 groups. RESULTS: Open-ward inpatients who have autonomy and various community service program were more satisfied with their general life than the others. Community residence outpatients spent more money and less assaults experience but their leisure activities and social contact frequencies were lower than in the inpatients. Outpatients were less satisfied with their health, finances and leasure activities. Inpatients had more leisure activities and higher social contact frequency than outpatients. They were more satisfied with their finances despite of spending less the money monthly than the outpatients. They experienced violence and damage more often for the past one year and were more satisfied with their health. CONCLUSION: The quality of life reported by chronic mental patients differed according to the characteristics of therapeutic environment. The life-quality of open-ward inpatients were the highest among the 3 groups. It is necessary to serve various community service program so that we can improve the life-quality of community residence outpatients.
Hospitals, Psychiatric ; Humans ; Inpatients ; Jeollanam-do ; Leisure Activities ; Mentally Ill Persons* ; Outpatients ; Quality of Life* ; Social Welfare ; Violence

Research study of Hepatitis B infection has been much advanced recently and the incidence of the Hepatitis B infection, such as acute viral hepatitis, chronic active hepatitis, chronic persistant hepatitis, acute fulminating hepatitis and carrier states are increasing significantly. The authors evaluated HBsAg and AntiHBs in the child age group and the results are summarized as follows: Of 271 children who were admitted during the period of June 1, 1981 to August 31, 1981, 15(5.9%) were HBsAg positive and 24(8.86%) were antiHBs positive. The highest incidence of HBs Ag among the children was school age group. The highest incidence of AntiHBs was newborn age group. Of 92 children who were living in the orphanage, 12(13.0%) were HBsAg positive and 8 (8.71%) were AntiHBs positive. There was no significant difference in comparison by each room.
Australia* ; Carrier State ; Child ; Hepatitis ; Hepatitis B ; Hepatitis B Surface Antigens* ; Hepatitis, Chronic ; Humans ; Incidence ; Infant, Newborn ; Orphanages ; Prevalence*

Research study of Hepatitis B infection has been much advanced recently and the incidence of the Hepatitis B infection, such as acute viral hepatitis, chronic active hepatitis, chronic persistant hepatitis, acute fulminating hepatitis and carrier states are increasing significantly. The authors evaluated HBsAg and AntiHBs in the child age group and the results are summarized as follows: Of 271 children who were admitted during the period of June 1, 1981 to August 31, 1981, 15(5.9%) were HBsAg positive and 24(8.86%) were antiHBs positive. The highest incidence of HBs Ag among the children was school age group. The highest incidence of AntiHBs was newborn age group. Of 92 children who were living in the orphanage, 12(13.0%) were HBsAg positive and 8 (8.71%) were AntiHBs positive. There was no significant difference in comparison by each room.
Australia* ; Carrier State ; Child ; Hepatitis ; Hepatitis B ; Hepatitis B Surface Antigens* ; Hepatitis, Chronic ; Humans ; Incidence ; Infant, Newborn ; Orphanages ; Prevalence*