1.A Retrospective Analysis of MRI-verified 29 Cases of Transverse Myelitis.
Young Rae KIM ; Jun Hyeok SONG ; Hyang Kwon PARK ; Sung Hak KIM
Journal of Korean Neurosurgical Society 2000;29(12):1642-1649
No abstract available.
Myelitis, Transverse*
;
Retrospective Studies*
2.A Case of Small Cell Carcinoma of the Ovary.
Jin Hak KIM ; Kwang Rae KIM ; Jong Il BAIK ; Yong Sang SONG ; Soon Beom KANG ; Hyo Pyo LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(2):82-87
Small cell carcinoma of the ovary has been identified as a specific histopathologic entity. The first II cases were reported by Dickersin et a1, 1982, Since then only 80 cases were reported in literature. This rare and highly aggresive melignancy primarily affeets ehildren and young women(10-40) and grows rapidly, with hypercalcemia occuring frequently. Abscence of effective treatment results in early mortality. Recently we have experienced one case of primary sma11 cell carcinoma of the ovary, which is presented with a brief review of the literature.
Carcinoma, Small Cell*
;
Female
;
Hypercalcemia
;
Mortality
;
Ovary*
3.A Sedimentation Level in Pituitary Adenoma on Magnetic Resonance Imaging.
Young Rae KIM ; Jun Hyeok SONG ; Hyang Kwon PARK ; Sung Hak KIM ; Kyu Man SHIN
Journal of Korean Neurosurgical Society 2001;30(4):519-521
We present a rare case of a pituitary adenoma revealing a sedimentation level on MRI, which has not been previously documented. This 55-year-old woman was referred with the diagnosis of craniopharyngioma. She presented with four-month history of progressive headache and visual dimness. Neurological examination revealed a bitemporal hemianopsia and decreased visual acuity. Laboratory data including endocrine examination were unremarkable. An additional three-dimensional MRI was taken for further evaluation, and demonstrated a sedimentation level within the tumor. The patient underwent transcranial removal of the tumor. About 12cc of dark-red blood was aspirated from the tumor. Histological examination revealed a pituitary adenoma with hemorrhage. Postoperatively, the patient showed gradual improvement of visual function. Considering that the pituitary adenoma is one of more common tumors that cause tumoral bleeding, a cystic sellar tumor that has a sedimentation level should be sought first for a pituitary adenoma rather than a craniopharyngioma. This may have an important impact when deciding surgical approach.
Craniopharyngioma
;
Diagnosis
;
Female
;
Headache
;
Hemianopsia
;
Hemorrhage
;
Humans
;
Magnetic Resonance Imaging*
;
Middle Aged
;
Neurologic Examination
;
Pituitary Apoplexy
;
Pituitary Neoplasms*
;
Visual Acuity
4.A Case of Central Diabetes Insipidus Caused by Metastatin Malignant Lymphoma.
Sung Kil LIM ; Young Duk SONG ; Hyun Chul LEE ; Kap Bum HUH ; Hyun Soo KIM ; Kyung Rae KIM ; Yoo Mi LEE ; Yong Suk YOON ; Suk Ho KWON ; Jae Hyun NAM ; Sang Hak LEE
Journal of Korean Society of Endocrinology 1997;12(4):596-601
The causes of central diabetes insipidus (CDI) are numerous; some primary cases are idiopathic while most secondary cases are surgically induced or the result of tumor. The frequency of metastatic tumor as a cause of DI is 6% to 20% of cases, Variety of malignancies including breast, lung, colon, prostate cancer, and leukemia/lymphoma have been reported to metastasize to the pituitary, although most patients are asymptomatic. Clinical manifestations of pituitary metastases include anterior pituitary failure, visual disturbance, and extraocular muscle weakness. DI is the most common clinical manifestation of hypothalamic-pituitary axis (HPA) metastases. Anatomical basis far this clinical picture is that most metastases occur in the posterior lobe. We report on a 35-year-old male patient with meningeal involvement of malignant lymphoma that was thought to be associated with DI. Confirmation of primary malignancy was made by biopsy at site of cervical lymph node and tonsil, Pituitary involvement was suspected on brain MRI, and satisfactory symptornatic relief was obtained with vasopressin. Because of the progres-sion of underlying lymphorna that has shown no response to combined anticancer chemotherapy, the patient expired on 60th hospital day.
Adult
;
Axis, Cervical Vertebra
;
Biopsy
;
Brain
;
Breast
;
Colon
;
Diabetes Insipidus, Neurogenic*
;
Drug Therapy
;
Humans
;
Lung
;
Lymph Nodes
;
Lymphoma*
;
Magnetic Resonance Imaging
;
Male
;
Muscle Weakness
;
Neoplasm Metastasis
;
Palatine Tonsil
;
Prostatic Neoplasms
;
Vasopressins
5.A Case of Recurrent Hydramnios in Association with Congenital Myotonic Dystrophy.
Yoon Sook KIM ; Seul Kee LEE ; Sung Taek MUN ; Hak Rae SONG ; Jae Gun SUNWOO ; Min Kwan KIM ; Dong Han BAE
Korean Journal of Obstetrics and Gynecology 2003;46(3):658-662
Hydramnios is a serious complication of pregnancy associated with a marked increase in perinatal mortality. A variety causes of this condition have been described, the majority of which relate to abnormalities of the fetus. Myotonic dystrophy is a progressive degenerative disease of the neuromuscular system, usually inherited in an autosomal dominant fashion. The disease is variable onset and clinical manifestations and usually severe in the male. Especially congenital myotonic dystrophy is a disease characterized by profound hypotonia. Affected infants present with varying degrees of respiratory failure, often necessitating immediate and prolonged ventilatory assistance. These neonates also have feeding difficulties due to impaired sucking and swallowing. The diagnosis of myotonic dystrophy in pregnancy is made retrospectively, following the birth of a severely affected neonates. A documented case of congenital myotonic dystrophy associated with hydramnios in two successive pregnancies is presented. The evidence suggests that myotonic dystrophy should be considered as a rare cause of recurrent hydramnios. We report a case of recurrent hyramnios in association with congenital myotonic dystrophy with a brief review of literatures.
Deglutition
;
Diagnosis
;
Fetus
;
Humans
;
Infant
;
Infant, Newborn
;
Male
;
Muscle Hypotonia
;
Myotonic Dystrophy*
;
Parturition
;
Perinatal Mortality
;
Polyhydramnios*
;
Pregnancy
;
Respiratory Insufficiency
;
Retrospective Studies
6.Ancient schwannoma in oral cavity: a report of two cases.
Na Rae KIM ; Dong Hae CHUNG ; Dae Song PARK ; Dong Woo KIM ; Sang Chil LEE ; Sung Yong KIM ; Ho Yong LIM ; Hak Yeol YEOM ; Hyeon Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2011;37(6):530-534
This paper reports two cases of schwannomas arising from the oral cavity. One is an intraoral ancient schwannoma located at the left cheek, which evolved over a period of 13 years. The tumor was a well-demarcated buccal mass, which was located in the left lower first premolar area, with an obliterated the buccal vestibule, leaving the overlying mucosa intact. The second case was a central intraosseous schwannoma located from the left lower 1st molar periapical area to the left 3rd molar periapical area. Pathologically, the first mass was composed of the spindle shaped tumor cells with wavy nuclei beneath the fibroconnective tissue of the gingiva but second case mass was not. Occasional nuclear pleomorphism was observed but mitosis or necrosis was absent. There were Antoni A and B areas along with strong, diffuse staining with the S-100 protein. Ancient schwannomas were diagnosed. Schwannoma is a slow-growing benign tumor, and an ancient schwannoma that shows cellular atypism is a variant of a schwannoma caused by purely degenerative changes. To date, only limited cases of ancient schwannomas in the oral cavity have been reported.
Bicuspid
;
Cheek
;
Gingiva
;
Mitosis
;
Molar
;
Mouth
;
Mucous Membrane
;
Necrosis
;
Neurilemmoma
;
S100 Proteins
7.A Multi-institutional Study on Histopathological Characteristics of Surgically Treated Renal Tumors: the Importance of Tumor Size.
Sun Il KIM ; Yeung Deuk CHOI ; Se Joong KIM ; Byung Ha CHUNG ; Do Hwan SEONG ; Chun Il KIM ; Sang Hyeon CHEON ; Jin Seon CHO ; Yun Seob SONG ; Young Sig KIM ; In Rae CHO ; Dong Hyeon LEE ; Ki Hak SONG ; Hong Sup KIM ; Joong Shik LEE ; Won Jae YANG ; Sung Joon HONG
Yonsei Medical Journal 2008;49(4):639-646
PURPOSE: The incidence of accidentally detected small renal tumors is increasing throughout the world. In this multi-institutional study performed in Korea, histopathological characteristics of contemporarily surgically removed renal tumors were reviewed with emphasis on tumor size. MATERIALS and METHODS: Between January 1995 and May 2005, 1,702 patients with a mean age of 55 years underwent surgical treatment at 14 training hospitals in Korea for radiologically suspected malignant renal tumors. Clinicopathological factors and patient survival were analyzed. RESULTS: Of the 1,702 tumors, 91.7% were malignant and 8.3% were benign. The percentage of benign tumors was significantly greater among those < or = 4cm (13.2%) than those > 4cm (4.5%) (p < 0.001). Among renal cell carcinoma patients, the percentage of tumors classed as stage > or = T3 was significantly less among tumors < or = 4cm (5.2%) than those > 4cm (26.8%) (p < 0.001). The percentage of tumors classed as Fuhrman's nuclear grades > or = 3 was also significantly less among tumors < or = 4cm (27.3%) than tumors > 4cm (50.9%) (p < 0.001). The 5-year cancer-specific survival rate was 82.7%, and T stage (p < 0.001), N stage (p < 0.001), M stage (p = 0.025), and Fuhrman's nuclear (p < 0.001) grade were the only independent predictors of cancer-specific survival. CONCLUSION: In renal tumors, small tumor size is prognostic for favorable postsurgical histopathologies such as benign tumors, low T stages, and low Fuhrman's nuclear grades. Our observations are expected to facilitate urologists to adopt function-preserving approach in the planning of surgery for small renal tumors with favorable predicted outcomes.
Adolescent
;
Adult
;
Aged
;
Aged, 80 and over
;
Female
;
Humans
;
Kidney Neoplasms/classification/*pathology/*surgery
;
Male
;
Middle Aged
;
Neoplasm Staging
8.Clinical comparisons of laparoscopically assisted vaginal hysterectomy and total vaginal hysterectomy.
Sam Yong SHIM ; Yun Seok YANG ; Young Rae SONG ; Sang Hun JUN ; Ki Hwan KIM ; Kyung Hwa KANG ; Byung Kwan LEE ; Jeong Hoon RHO ; Kwan Young OH ; In Taek HWANG ; Ji Hak JEONG ; Joon Suk PARK
Korean Journal of Obstetrics and Gynecology 2006;49(1):147-156
OBJECTIVE: To compare the clinical results between laparoscopically assisted vaginal hysterectomy (LAVH) and total vaginal hysterectomy (TVH). METHODS: We reviewed the medical records of patients who underwent LAVH and TVH from January 2002 to December 2004 in 00 university hospital without the history of uterine prolapse or pelvic relaxation. We evaluated age, parity, previous abdominal operations, indication of hysterectomy, size of the uterus, operation time, hemoglobin change, hospital day, the degree of postoperative pain and initiation of diet and postoperative complications. RESULTS: The age and parity of the patients in both groups were not different statistically. There were history of previous abdominal operations in 20.8% of LAVH group and 25.3% of TVH group which didn't have statistic significance. Major indications of the operation were uterine myomas in both groups. The average weight of the extracted uterus were 272.9+/-114.5 gm and 225.6+/-87.0 gm in the LAVH group and the TVH group respectively which had significance, and the operation time were 81.1+/-23.4 minutes and 71.1+/-37.8 minutes respectively which had significance. There were no difference in the hemoglobin drop of the postoperative day 1, but the hemoglobin drop of the postoperative day 4 was larger in the LAVH group. Postoperative complications occurred more often in the TVH group (15.2%) than LAVH group (11.9%) but didn't have significance, and the complications were treated by conservative managements and observation of the progress. And also the hospital day, the degree of postoperative pain and initiation of diet had no significance. CONCLUSION: Both LAVH and TVH had no statistic difference in the postoperative morbidity and recuperation. Moreover the indications of operation for both surgeries had no statistic difference, but LAVH had a preference for the larger size of uterus. Furthermore in order to increase the satisfactions of patients and remedy the weak points of procedures, research on the indications and contra-indications between the operative approaches and training on the operative procedures are required.
Diet
;
Female
;
Humans
;
Hysterectomy
;
Hysterectomy, Vaginal*
;
Leiomyoma
;
Medical Records
;
Pain, Postoperative
;
Parity
;
Postoperative Complications
;
Relaxation
;
Surgical Procedures, Operative
;
Uterine Prolapse
;
Uterus
9.Clinical significance of Doppler velocimetry and oligohydramnios in intrauterine growth restriction.
Sam Yong SHIM ; Mi Hye PARK ; Kwan Young OH ; Sang Hun JUN ; Young Rae SONG ; Jeong Hoon RHO ; Byung Kwan LEE ; Kyung Hwa KANG ; Ki Hwan KIM ; In Taek HWANG ; Yoon Seok YANG ; Ji Hak JEONG ; Joon Suk PARK
Korean Journal of Obstetrics and Gynecology 2006;49(2):345-356
OBJECTIVE: The aim of this study is to prove the clinical significance by evaluating pregnancy outcomes from intrauterine growth restriction using waves of the Doppler velocimetry of uterine and umbilical artery and amniotic fluid index. METHODS: Throughout the period of January 2000 to May 2005 at our hospital, we reviewed 127 cases diagnosed with intrauterine growth restriction after 24 weeks of pregnancy and the existences of diastolic notch of uterine artery (DNUT), absent or reversed end-diastolic velocity of umbilical artery (AEDV) and oligohydramnios were considered abnormal. We set the group that had no abnormal signs as the control group (62 cases), and respectively compared the groups that had oligohydramnios (24 cases), unilateral DNUT (27 cases), bilateral DNUT (10 cases) and AEDV (13 cases) with the control group. And we compared the groups that had only one abnormal sign, that is oligohydramnios (20 cases), bilateral DNUT (7 cases), AEDV (7 cases) and the group showing 2 or more complicated abnormal signs those above (9 cases) with the control group. RESULTS: Perinatal outcomes such as preterm birth, low birth weight, lower 5-min Apgar score (A/S), neonatal acidosis, admission rate of neonatal intensive care unit (NICU) and perinatal mortality were poor statistically in groups with DNUT, AEDV and oligohydramnios compared to those which have none of these abnormal signs. And those with DNUT had worse results when affected on both sides. And those with AEDV showed worse perinatal outcomes compared to those with bilateral DNUT or oligohydramnios; any overlapping of these abnormal signs indicated worse perinatal outcomes, which had statistic significance. CONCLUSION: Close observation of the fetal well-being by analysis on the wave velocimetry of the blood flow such as the uterine arteries and umbilical arteries and the measurement of the amniotic fluid volume enables predicting the perinatal prognosis of the intrauterine-growth restricted fetuses which may contribute in reducing the perinatal morbidity and mortality.
Acidosis
;
Amniotic Fluid
;
Apgar Score
;
Female
;
Fetus
;
Humans
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Mortality
;
Oligohydramnios*
;
Perinatal Mortality
;
Pregnancy
;
Pregnancy Outcome
;
Premature Birth
;
Prognosis
;
Rheology*
;
Umbilical Arteries
;
Uterine Artery
10.Prostate-Specific Antigen Test Interval according to Baseline Prostate-Specific Antigen and Age.
Moon Sik KWON ; Cheol Young OH ; Chang Hee YOO ; Sun Il KIM ; Se Joong KIM ; Dong Jun KIM ; Young Sik KIM ; Chun Il KIM ; Hong Sub KIM ; Do Hwan SEONG ; Ki Hak SONG ; Yun Seob SONG ; Won Jae YANG ; Dong Hyeon LEE ; Sang Hyeon CHEON ; In Rae CHO ; Byung Ha CHUNG ; Young Deuk CHOI ; Sung Joon HONG ; Hyoungjune IM ; Jin Seon CHO
Korean Journal of Urology 2009;50(11):1059-1065
PURPOSE: The optimal interval at which to repeat prostate-specific antigen (PSA) measurement is controversial. We evaluated the probability of the serum PSA value increasing above specific cutoff values (4.0 ng/ml, 3.0 ng/ml, and 2.5 ng/ml) on annual follow-up visits in men with a lower baseline PSA than each cutoff value. MATERIALS AND METHODS: Between 2002 and 2006, a total of 14,459 men aged 40 to 79 years who underwent serum PSA determinations at least twice during health examinations at 11 medical centers were enrolled in this study. To reduce probable bias, we excluded men with pyuria, those with a baseline or follow-up PSA level of 10.0 ng/ml or more, and those with a history of medication with 5 alpha-reductase inhibitors. Serum PSA underwent logarithmic conversion to work out the normal distribution. The cumulative rate of freedom from increase in PSA above 4.0 ng/ml, 3.0 ng/ml, and 2.5 ng/ml was estimated with the Kaplan-Meier method according to baseline PSA range and age. The significance level was 1%. RESULTS: The rate of increase in PSA was lower in men who had a baseline PSA value in the low range and whose age was in the 40s or 50s. However, the cumulative rate of freedom from increase in PSA decreased as the PSA cutoff value was lowered. The optimal screening interval for men in their 40s and 50s whose baseline serum PSA level was 1.0 ng/ml or lower was 3 years when the significance level for PSA rising above 4.0 ng/ml was 1%. It was 2 years and 1 year, respectively, when the cutoff value was lowered to 3.0 ng/ml or 2.5 ng/ml. An annual PSA screening interval was recommended in men older than their 60s. CONCLUSIONS: The PSA test interval should be individualized according to baseline PSA, age, and PSA cutoff value.
Aged
;
Bias (Epidemiology)
;
Cholestenone 5 alpha-Reductase
;
Follow-Up Studies
;
Freedom
;
Humans
;
Male
;
Mass Screening
;
Prostate-Specific Antigen
;
Pyuria