1.The Statistical Study of The Lateral Tibio
Hyeung Seok KIM ; Ki Do HONG ; Soon Hak HONG
The Journal of the Korean Orthopaedic Association 1988;23(5):1255-1258
The study was conducted to determine the lateral tibio-articular angle of ankle joint in 100 korean adults(160 cases) ranging from second to eight decades of age. The authors have defined as the lateral tibio-articular angle of ankle joint, that is the sharp angle between the lateral tibial axis which is the lateral longitudinal line through each midpoints of the upper and lower one third of the tibia, and the line to connect the anterior and posterior tips of the tibial articular surface of ankle joint. 1. It was 79.3°±3.4°in all cases. 2. It was 79.2°±3.6°in male and 79.6°±2.7°in female. It was reduced in male approximately 0.4°compared with female. 3. It was 79.1°±3.1°in the left side and 79.5°±3.6°in the right side. It was reduced approximately 0.4°in the left side compared with the right side. 4. It was reduced approximately 0.9°in the left side compared with both sides of the same person.
Adult
;
Ankle Joint
;
Ankle
;
Female
;
Humans
;
Male
;
Statistics as Topic
;
Tibia
2.Correlation of Proliferating Cell Nuclear Antigen (PCNA) Expression and S-phase Fraction, Survival Rate in Primary Non-Small Cell Lung Cancer.
Sei Hoon YANG ; Hak Ryul KIM ; Ki Seon GU ; Byung Hak JUNG ; Eun Taik JEONG
Tuberculosis and Respiratory Diseases 1997;44(4):756-765
BACKGROUND: To study the prognosis of patients with lung cancer, many investigators have reported the methods to detect cell proliferation in tissues including PCNA, thymidine autoradiography, flow cytometry and Ki-67. PCNA, also known as cyclin, is a cell related nuclear protein with 36KD intranuclear polypeptide that is maximally elevated in S phase of proliferating cells. In this study, PCNA was identified by paraffin-embedding tissue using immunohistochemistry which has an advantage of simplicity and maintenance of tissue architecture. The variation of PCNA expression is known to be related with proliferating fraction, histologic type, anatomic(TNM) stage, degree of cell differentiation, S-phase fraction and survival rate. We analyzed the correlation between PCNA expression and S-phase fraction, survival. METHODS: To investigate expression of PCNA in primary lung cancer, we used immunohistochemical stain to paraffin-embedded sections of 57 resected primary non-small cell lung cancer specimen and the results were analyzed according to the cell type, cell differentiation, TNM stage, S-phase fraction and survival. RESULTS: PCNA expression was dMded into five group according to degree of staging(-, +, ++, +++,++++). Squamous cell type showed high positivity than in adenocarcinoma. Nonsignificant difference related to TNM stage was noticed. Nonsignificant difference related to degree of cell differentiation was noticed. S-phase fraction was increased wit advance of PCNA positivity, but t could not reach the statistic significance. The 2 year survival rate and median survival time were -50% 13 months, +75% 41.3 months, ++73% 33.6 months, +++67% 29.0 months, ++++25% 9 months with statistic significance (P<0.05, Kaplan-Meier, generalized Wilcox). CONCLUSION: From this study. PCNA expression was high positive n squamous cell cancer. And, there was no relationship between PCNA positivity and TNM stage, cellular differentiation or S-phase fraction. But, the patients with high positive PCNA staining showed poor survival rate than the patients with lower positive PCNA. It was concluded that PCNA immunostaining is a simple and useful method for survival prediction in paraffin embedded tissue of non-small cell lung cancer.
Adenocarcinoma
;
Autoradiography
;
Carcinoma, Non-Small-Cell Lung*
;
Cell Differentiation
;
Cell Proliferation
;
Cyclins
;
Flow Cytometry
;
Humans
;
Immunohistochemistry
;
Lung Neoplasms
;
Neoplasms, Squamous Cell
;
Nuclear Proteins
;
Paraffin
;
Prognosis
;
Proliferating Cell Nuclear Antigen*
;
Research Personnel
;
S Phase
;
Survival Rate*
;
Thymidine
3.EMA-CO regimen in high-risk gestational trophoblastic disease.
Sang Lim CHOI ; Yong Hak KIM ; Ki Tae KIM ; Hyun Chan KIM
Korean Journal of Obstetrics and Gynecology 1992;35(1):85-96
No abstract available.
Gestational Trophoblastic Disease*
4.Induction chemotherapy in locally advanced cervical cancer.
Yong Hak KIM ; Byung Gyu YOO ; Ki Tae KIM ; Hyun Chan KIM
Korean Journal of Obstetrics and Gynecology 1992;35(9):1288-1299
No abstract available.
Induction Chemotherapy*
;
Uterine Cervical Neoplasms*
5.Detection of hepatitis B virus DNA in serum by digoxigenin labeled DNA probe.
Su Hee KIM ; Won Ki BAEK ; Min Ho SUH ; Jae Ryong KIM ; Dong Hak SHIN
Journal of the Korean Society for Microbiology 1993;28(4):303-311
No abstract available.
Digoxigenin*
;
DNA*
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
6.Arterial Embolization for Management of Hemoptysis.
Sung Min KIM ; Young Ju KIM ; Ki Joon SUNG ; Hak Seok YANG ; Myung Sub LEE
Journal of the Korean Radiological Society 1994;30(6):1029-1034
PURPOSE: Our purpose in this study is to evaluate the effectiveness of bronchial and nonbronchial systemic arteries for the control of hemoptysis. MATERIALS AND METHODS: Seventy patients with massive or recurrent hemoptysis underwent percutaneous transcatheter embolotherapy between 1991 and 1993. Retrospectively we reviewed 77 cases of bronchial artery embotization and 32 cases of nonbronchial systemic artery embolization in the 70 patients. RESULTS: Immdiate control of hemoptysis was achieved in 33 of 39 patients with massive hemoptysis(84.6%) and 20 of 24 patients with recurrent hemopt ysis(83.3%). In 32 cases, nonbronchial systemic arteries contributed significantly to areas of pathologic pulmonary tissue and frequently were the major arterial supply. CONCLUSION: Bronchial artery embolization is an effective and life saving procedure in non-surgical candidates. Recognition and occlusion of nonbronchial systemic arteries that feed to hypervascular pulmonary lesions is essential for successful percutaneous embolotherapy of hemoptysis.
Arteries
;
Bronchial Arteries
;
Embolization, Therapeutic
;
Hemoptysis*
;
Humans
;
Retrospective Studies
7.Unilateral pulsatile tinnitus: A case report.
Hong Chul KIM ; Tae Hyun YOON ; Ki Cheon LEE ; Seong Hak KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):342-346
No abstract available.
Tinnitus*
8.A Case of Moyamoya Disease with Focal Seizure.
Man Gee HONG ; Hak Ki KIM ; Kyung Tai WHANG ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1982;25(10):1053-1057
No abstract available.
Moyamoya Disease*
;
Seizures*
9.Change of Serum IGF-I and IGFBP-3 Concentration During Induction Chemotherapy in Children with Acute Lymphocytic Leukemia.
Jee Yeon SONG ; Bin CHO ; Hak Ki KIM ; Byung Churl LEE
Journal of Korean Society of Pediatric Endocrinology 1997;2(1):53-59
PURPOSE:The most important regulatory factor for IGF-I and IGFBP-3 known so far GH and food intake. Poor nutrition in children with acute lymphocytic leukemia(ALL) increase morbidity during treatment. The aim of this study was to assess the changes of serum IGF-I and IGFBP-3 concentration during induction chemotherapy in 13 children with acute lymphocytic leukemia. METHODS:13 children aged between 1.6 and 13.5 years with ALL were studied the changes of serum IGF-I and IGFBP-3 concentration before, at 2 and 4 weeks after induction chemotherapy. Serum IGF-I and IGFBP-3 were measured using radioimmunoassay. Results : 1) Mean serum IGF-I and IGFBP-3 concentration before induction chemotherapy in ALL patient was significantly lower than the those of normal control(p<0.05). 2) Mean serum IGF-I and IGFBP-3 concentration at 2 weeks of induction chemotherapy were significantly higher than the those of the basal levels (p<0.05). 3) Mean serum IGF-I and IGFBP-3 concentration at 4 weeks after induction chemotherapy were significantly higher than the those of the basal levels (p<0.05). Conclusion : Concentration of serum IGF-I and IGFBP-3 in patients with ALL were significantly increased during induction chemotherapy. These results are probably related to improvement of nutritional status following induction chemotherapy.
Child*
;
Eating
;
Humans
;
Induction Chemotherapy*
;
Insulin-Like Growth Factor Binding Protein 3*
;
Insulin-Like Growth Factor I*
;
Nutritional Status
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Radioimmunoassay
10.A case of hepatic hydrothorax.
In Soo HONG ; Hak Suk YANG ; Ki Joon SUNG ; Myung Soon KIM
Korean Journal of Nuclear Medicine 1992;26(2):392-395
No abstract available.
Hydrothorax*