1.Experimental otitis media with effusion induced by lipopolysaccharides from E. coli: the effects of endotoxin to the chronically of OME.
Hak Hyun JUNG ; Jong Ouck CHOI ; Hong Kyun YOO
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):879-894
No abstract available.
Lipopolysaccharides*
;
Otitis Media with Effusion*
;
Otitis Media*
;
Otitis*
2.Characterization of Unstable Bladder in the Rat with Infravesical Outlet Obstruction.
Hee Chang JUNG ; Tong Choon PARK ; Ki Hak MOON ; Jun Kyu SUH ; Jung Hyun KIM
Journal of the Korean Continence Society 1999;3(1):15-20
No abstract available.
Animals
;
Calcium
;
Rats*
;
Urinary Bladder*
3.Serum Insulin-like Growth Factors and their Binding Proteins in the Women With Polycystic Ovary.
Jae Sook ROH ; Jung Bae YOO ; Soo Hyun JO ; Hak Soon KIM ; Yoon Yeong HWANG
Korean Journal of Obstetrics and Gynecology 2000;43(5):795-805
OBJECTIVE: The involvement of IGF system in hyperandrogenism and abnormal follicular development is controversial. This study is to assess whether IGF system contribute to it in the women with polycystic ovary(PCO). METHODS: Baseline serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E2), testosterone (T), androstenedione (ADD), prolactin, thyroid stimulating hormone (TSH), free insulin-like growth factor(IGF)-I, free IGF-II, insulin-like growth factor binding protein(IGFBP)-1, and IGFBP-3 were measured in twelve healthy regularly cycling volunteers and forty-two women with PCO then, the changes of baseline serum levels were evaluated after laparoscopic ovarian electrocauterization in nine PCO patients. In addition, the expression pattern of IGF-I and IGF-II was examined in the ovary of control and PCO group. RESULTS: Baseline levels of LH, ADD, free IGF-II, and IGFBP-3 were significantly higher in PCO group. However, there were no significant differences in the levels of free IGF-I and IGFBP-1, although free IGF-I showed decreasing tendency in PCO group. And there was a significant positive correlation between the LH and free IGF-II level in the PCO(P=0.011, r2=0.3899), but not in the control. After ovarian electrocauterization, LH, T, and ADD levels decreased, and free IGF-I and IGFBP-3 level increased. While free IGF-II and IGFBP-1 level showed no significant changes. In the ovary, expression of both IGFs showed similar pattern in normal and PCO ovaries. CONCLUSIONS: The elevated IGFBP-3 level may alter the bioavailability of IGF(s) in the PCO. The change in IGF-I level and resumption of ovulation after electrocauterization, suggest a possible role of IGF system in the impairment of follicular development in the PCO.
Androstenedione
;
Biological Availability
;
Carrier Proteins*
;
Estradiol
;
Female
;
Follicle Stimulating Hormone
;
Humans
;
Hyperandrogenism
;
Insulin-Like Growth Factor Binding Protein 1
;
Insulin-Like Growth Factor Binding Protein 3
;
Insulin-Like Growth Factor I
;
Insulin-Like Growth Factor II
;
Luteinizing Hormone
;
Ovary*
;
Ovulation
;
Prolactin
;
Somatomedins*
;
Testosterone
;
Thyrotropin
;
Volunteers
4.A Case of Aplasia Cutis Congenita Group 5.
Jung En KWON ; Sang Hee KIM ; Gwang Hoon LEE ; Kil Hyun KIM ; Hak Soo LEE
Journal of the Korean Society of Neonatology 1997;4(2):272-275
Aplasia cutis congenita is a rare disorder characterized by localized or generalized absence of skin at birth. The various hypothesis and classification are proposed. Type V in Frieden's classification, which is associated with fetus papyraceus or placental infarcts, occurs as a large cutaneous defect on the trunk and extremities. We experienced the patient had skin defect affecting the lower abdomen symmetrically, with no family history of the any disorders or chromosomal anomalies and associated anomalies. A twin fetus was died in utero. We report a case of aplasia cutis congenita associated with fetus papyraceus with the review of the associated literatures.
Abdomen
;
Classification
;
Ectodermal Dysplasia*
;
Extremities
;
Fetus
;
Humans
;
Parturition
;
Skin
;
Twins
5.Acute appendicitis in children.
Dong Hak SHIN ; Jung Hee KIM ; Chul Young BAE ; Woo Hyun PARK
Journal of the Korean Academy of Family Medicine 1992;13(1):20-27
No abstract available.
Appendicitis*
;
Child*
;
Humans
6.Periventricular leukomalacia: Ultrasonographic findings, risk factors and neurological outcome.
Kyeong Hee CHO ; Myoung Jae CHEY ; Se Jung SOHN ; Kil Hyun KIM ; Hak Soo LEE
Journal of the Korean Pediatric Society 1993;36(5):693-704
The thirty eight newborn infants with periventricular leukomalacia who were admitted to the neonatal intensive care unit of Gil General Hospital from March 1, 1988 to June 30, 1991, were investigated for ultrasonographic findings, risk factors and neurological outcome. The results were as follows: 1) There were 38 cases of PVL including 21 echogenic flarings and 17 cystic PVL's. 2) Mean birth weight was 2,250 gm and mean gestational age was 35 week. 3) Mean detection timing was 4th day in echogenic flarings and 18th day in cystic PVL's. 4) PVL's were located in the parietal region in 1 case and fronto-parieto-occipital in 3 cases. 5) Mean cyst size was 6 mm. 6) Multiple logistic regression analysis for the risk factors of PVL showed that low birth weight, apnea and seizure were the most significant contributing factors (p<0.05). 7) In the follow-up study of cystic PVL's, 7 cases showed improvement, 7 cases developed into multicystic encephalomalacia and 3 cases developed into atrophy. 8) Neurodevelopmental outcome of cystic PVL's showed nomal; 6.2%, minor neurodevelopmental defect; 43.8%, major neurodevelopmental defect; 31.2% and death; 18.8%. 9) Neurosonographic predictability for neurodevelopemental sequelae by cystic PVL's showed sensitivity; 63.6%%, specificity; 98.0%, positive predictive value; 92.8% and accuracy; 88.2%. 10) Major neurodevelopmental defect was more frequent, cyst size being larger and location being more extensive (p<0.05).
Apnea
;
Atrophy
;
Birth Weight
;
Encephalomalacia
;
Follow-Up Studies
;
Gestational Age
;
Hospitals, General
;
Humans
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Leukomalacia, Periventricular*
;
Logistic Models
;
Rabeprazole
;
Risk Factors*
;
Seizures
;
Sensitivity and Specificity
8.Primary endodermal sinus tumor of the common bile duct.
Kyeong Hee CHO ; Se Jung SOHN ; Kil Hyun KIM ; Hak Soo LEE
Journal of the Korean Pediatric Society 1992;35(9):1298-1302
No abstract available.
alpha-Fetoproteins
;
Common Bile Duct*
;
Endoderm*
;
Endodermal Sinus Tumor*
9.Epithelial regeneration and problems of ethmoidectomized cavity after endoscopic sinus surgery with extended ethmoidectomy.
Hak Hyun JUNG ; Chan Seung HWANG ; Soon Young KYUN ; Sun Hee LEE ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(6):1221-1229
No abstract available.
Regeneration*
10.Prognostic significance of mastoid pneumatization in childhood otitis media with effusion: temporal bone CT evaluation.
Hak Hyun JUNG ; Jong Ouck CHOI ; Jong Whan LEE ; Hong Kyun YOO
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):828-833
No abstract available.
Mastoid*
;
Otitis Media with Effusion*
;
Otitis Media*
;
Otitis*