No abstract available.
Adenocarcinoma* ; Rectum*

No abstract available.
Dermatitis, Allergic Contact* ; Fusidic Acid* ; Sodium*

Paraneoplastic cerebellar degeneration (PCD), the one of rare paraneoplastic syndromes, refer to clinical disorders associated mostly with lung, ovarian and breast cancer, but not directly caused by cancer or its metastasis. PCD is a condition whereby the Purkinje cells of the cerebellar cortex are damaged secondary to an autoimmune process. We report here on the case of PCD of subacute onset in a patient at 7 months after surgery for ovarian cancer. Although the cases of PCD has rarely been reported, the present case appears to be the first in Korea in which PCD was associated with anti-Yo antibody in patient with chemotherapy-responsive ovarian cancer. The clinical significance of PCD associated with anti-Yo antibody is reviewed.
Breast Neoplasms ; Cerebellar Cortex ; Humans ; Korea ; Lung ; Neoplasm Metastasis ; Ovarian Neoplasms ; Paraneoplastic Cerebellar Degeneration ; Paraneoplastic Syndromes ; Purkinje Cells

No abstract available.
Leiomyoma*

We report on a 28 years old female with recurred cardiac myxomas who presented with dizziness, headache, and blurred vision. She had an excision of biatrial atrial myxomas 10 years age. Varying sized multiple cerebral aneuysms and myxomas in left atrium and left ventricle were found on a cerebral angiogram and echocardiogram, respectively. After wide excision including interatrial septum and part of left ventricular septum, her symptoms were much improved.
Adult ; Dizziness ; Female ; Headache ; Heart Atria ; Heart Ventricles ; Humans ; Intracranial Aneurysm ; Myxoma* ; Ventricular Septum

OBJECTIVE: To determine the incidence of HELLP (hemolysis, elevated liver enzymes and low platelet count) syndrome and assess the relationship between the maternal-fetal complications and the severity of HELLP syndrome, classified based on platelet count nadir. METHODS: We reviewed the maternal and neonatal charts of ten pregnancies complicated by HELLP syndrome, managed at Dankook University Hospital between January, 1995 and December, 2002. Women were divided into 2 groups as class I HELLP which had a maternal platelet nadir 50,000 and 100,000/mm3. We compared the maternal and fetal complications between class I and class II HELLP syndrome. But we did not analyze statistically due to small number of patients. RESULTS: There were four cases of class I HELLP and six cases of class II HELLP syndrome. The incidence of HELLP syndrome was 0.10% (10/10,238) in total deliveries and was 2.26% (10/443) in women with severe pre-eclampsia or eclampsia. The mean level of platelet counts nadir was 41,500/mm3 in class I and 64,000/mm3 in class II HELLP. The mean platelet recovery days (more than 100,000/mm3) were 6.0 and 4.2 days in each class. The mean values of the maximal aspartate aminotransferase (AST/SGOT), alanine aminotransferase (ALT/SGPT) and uric acid might show no differences, but there might be difference in lactate dehydrogenase (LDH) levels which were 5854 and 1388 IU/L in each class. All patients with class I HELLP syndrome showed maternal complications, but only one patient with class II HELLP showed maternal complications. There might be no differences in the mean gestational ages and birth weights. The neonatal complications were similar in each class. CONCLUSION: Our data suggest that patients with class I HELLP syndrome may be at increased risk for serious maternal complications, but the neonatal complications may be associated with gestational ages.
Alanine Transaminase ; Aspartate Aminotransferases ; Birth Weight ; Blood Platelets* ; Eclampsia ; Female ; Gestational Age ; HELLP Syndrome* ; Humans ; Incidence ; L-Lactate Dehydrogenase ; Liver ; Platelet Count* ; Pre-Eclampsia ; Pregnancy ; Uric Acid

Diagnosis of knee jont pathology has been mainly dependent on clinical manifestations and invasive proceduressuch as arthrography and arthroscopy etc. However, these procedures are invasive. Arthroscopy is perfromed undergeneral anesthesia. Recently, with development of high resuloution CT with thin slices and multiplanarreconstructions capability, CT could be used to verify the internal structures of knee joint in noninvasive orless invasive way. From June ot December 1985, authors have experienced 19 cases of the knee joint CT. Among them,13 cases were operated and confirmed. We concluded as follows. 1. The diagnostic accuracy of the knee CT was 100%in lateral meniscal tearing, 92.3% in medial meniscal tearing, 92.3% in detachment of lateral collateral ligament,92.3% in medial collateral ligament, 100% in tearing of cruciate ligaments. 2. CT could be considered as a primarydiagnostic procedure in the knee pathology rather than more invasive arthrocopy or arthrography. 3. For theaccurate diagnosis of knee joint pathology, CT which can obtain thin slies, high resolution, multiplanarreconstructions is indispensable.
Anesthesia ; Arthrography ; Arthroscopy ; Collateral Ligaments ; Diagnosis ; Knee Joint ; Knee ; Ligaments ; Pathology ; Tears

PURPOSE: We evaluated the usefulness of a CT guided percutaneous transthoracic cutting needle biopsy (PCNB) using a 20 gauge (G) needle for pulmonary lesions after a comparison with the use of an 18 G needle for diagnostic accuracy and complications. MATERIALS AND METHODS: From August 2005 to July 2007, 433 patients underwent a CT guided PCNB. A total of 191 patients were excluded from the study as these patients had benign lesions seen after PCNB, but did not receive a confirmation biopsy or undergo follow-up (> 1 year). We evaluated the diagnostic accuracy for the use of PCNB using the Chi-squared test and analyzed which factors (location and size of lesions, diameter of the needle, distance between the pleura and lesions, presence or not of emphysema) were related to occurrence of a pneumothorax after PCNB using a multi-variant regression test. RESULTS: The diagnostic accuracy for malignant lesions with the use of an 18 G and a 20 G needle were 95.4% and 97%, respectively. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for the use of an 18 G needle were 95.7 %, 100%, 100%, and 91.6%. The sensitivity, specificity, PPV, and NPV were 97.8%, 100%, 100%, and 95.0% for the use of a 20 G needle. A pneumothorax occurred in 5.5% (24/433) of the cases and was closely related to the distance from the pleura to the lesions. CONCLUSION: CT guided PCNB with the use of a 20 gauge needle provided good diagnostic accuracy and the procedure is safe to perform.
Biopsy ; Biopsy, Needle ; Follow-Up Studies ; Humans ; Lung ; Lung Diseases ; Needles ; Nitrobenzenes ; Pleura ; Pneumothorax ; Sensitivity and Specificity

The purpose of this study was to investigate the maximum effect and effective instillation time interval of 5% NaCl on the corneal edema. Onetenth ml of 2% lidocaine was injected intracamerally to make the corneal edema at right eyes of four rabbits, but any manipulation was not done on the left eyes. Twelve hours after the operation, one drop of 5% NaCl was instillated in both eyes and the central corneal thickness(CCT)was measured every 30 minutes until the three successive records had no demonstrable changes compared to baseline levels. Maximum effect on normal cornea and corneal edema showed at 60 minutes after the instillation of one drop of 5% NaCl;the CCT decreased by about 5% compared to preopertaive level. To evaluate the effective instillation time interval, twenty eyes of 20 white rabbits were randomly divided into 5 groups and 0.1 ml of 2% lidocaine was injected intracamerally at right eyes. In control group, they were remained without any medications and showed natural course of corneal edema. 7In group 1, they were treated with 5% NaCl every 30 minutes and in group 2, 60 minutes, in group 3, 120 minutes, and in group 4, 180 minutes. Using a ultrasonic pachymeter, CCT was measured at 30 minutes interval up to 360 minutes. In group 1, decrease of the CCT was found to be more than 5% at 60 minutes after treatment and there was 5.00~7.24% decrease of CCT up to 360 minutes. In group 2 and 3, decrease of the CCT more than 5% was found at 90 minutes after treatment and there was 3.95~6.07% decrease of CCT up to 360 minutes.In group 4, decrease of the CCT more than 5% was found at 90 minutes after treatment and there was severe fluctuation of the decrease of the CCT from 2.47% to 6.78% up to 360 minutes. In group 1, decrease of the CCT was larger than that of the others, but there was chances of the corneal epithelial toxicity and incovenience due to frequent instillation. In group 2 and 3, there was no difference between the two groups in the amounts of the decrease of the CCT, but in terms of convenience, instillation every 2 hours(120 minutes)was recommendable. Treatment with 5% NaCl every 2 hours on corneal stromal edema with normal epithelial barrier function can decrease the CCT and induce good maintenance effect.
Cornea ; Corneal Edema* ; Edema ; Lidocaine ; Ophthalmic Solutions* ; Rabbits ; Ultrasonics

Adenomatoid hyperplasia of the minor salivary glands is a rare clinicopathologic entity with an unknown etiology. The clinical features of the lesion are nodular, non-painful swellings, and the histologic features are aggregates of normal-appearing, salivary gland tissue, in excess of what would be anticipated for the anatomic site. This tumor is of significance because of its clinical resemblance to salivary gland tumors. Although this lesion may occur at any site on the oral mucosa, the labial mucosa is known to be the least common site. We herein report a rare case of adenomatous hyperplasia of the minor salivary glands located on the lower labial mucosa.
Hyperplasia* ; Mouth Mucosa ; Mucous Membrane ; Salivary Glands ; Salivary Glands, Minor*