A total of 42 vas anastomoses was performed on experimental animals and successful anastomoses were obtained 19 of the cases and the over-all rate of success was approximately 46 per cent. But 13 dogs in total of 21 dogs were found to be patent in at least one side of vas, or about 65 per cent of total dogs were restored their fecundity. Splinting materials used in this comparative study are chromic catgut, stainless steel wire, dermalon and polyethylen tube, and dermalon has been proved as the most excellent splinting material among thembecause it is no figid but plable and makes no tissue reaction in the vas. Successful anastomosis of vas deferent is affected by many factors. Among these, an inadequate splinting material has been considered as the most important causes of failures. But it should seem that minimal dissection of the tied points of vas as satisfactory approximation of the free ends of vas exert very important effect upon the successful anastomosis as the splinting material does. Consecutive four successful anastomosis of human cases are highly satisfactory results and are very encouraging even in a small series of cases of the present study.
Animals* ; Catgut ; Dogs ; Fertility ; Humans* ; Nylons ; Splints* ; Stainless Steel ; Vasectomy*

About 60,000 men were undergone voluntary sterilization by the 497 designated doctors during the period from 1962 to October 1965 by the government subsidy program. Besides these numbers more than 15,000 private cases were sterilized by private doctors during the period from 1960 to 1964 in Korea. A general comprehension of the sterilization operation for motivation of customers was illustrated. An analysis of the social history and background of the sterilized men were made on the author's private group and the subsidized group. The most common occupation of the private group was commerce and that of the subsidized group was africulture. The duration intervening between marriage and sterilization indicated 13.6 years in the private group and 16.7 years in the subsidized group. An average age of the sterilized men showed 40 and that of their wives 35. An average number of children of the private group showed 4.7 while that of subsidized group indicated 5.3. Sexual drive following the sterilization was not changed in 81 per cent of the private group and in 71 per cent of the subsidized group. Decrease in sexual activity was revealed in 5 per cent of the private group but in 11 per cent of the subsidized group. General health after the sterilization was not changed in 83 per cent of the private group and in 70 per cent of the subsidized group. Decrease in general health was noted in only 6 per cent of the private group but in 11 per cent of the subsidized group. Frequency of sexual intercourse per week of the private group indicated 1.95 times preoperatively and 1.88 times postoperatively whereas that of the subsidized group revealed 2.27 times preoperatively but 1.99 times postoperatively. In regarding the sexual feeling of their wives, more than 87 per cent of the private group showed no change before and after the operation while 71 per cent of the wives of the subsidized group were not changed. Very few wives of the private group complained of some decrease, but 10 per cent of the subsidized group complained decrease. The time lost from work after the sterilization was about 2 days in the private group while about 8 days in the subsidized group. About 93 per cent of the private group were satisfied with the sterilization but 2 per cent of them did not feel happy after the operation. In the subsidized group 88 per cent were satisfied with the operation but 10 per cent were not satisfied. All of the private group and 80 per cent of the subsidized group would recommend the sterilization method to their friends. Untoward effects on sexual drive and general health are found to be higher in the subsidized group than in the private group. These outcomes are partly due to low edcation and low income of the subsidized group compared with the private group and partly due to unsatisfactory operative technique of the designated doctors. Psychological studies by means of MMPI conducted on 20 sterilization neurosis patients and the results were compared with the control nonvasectomized group. The sterilized group had definite psychological instability so that a preoperative psychological interview is found to invariably be necessary to prevent the sterilization neurosis. It is concluded by this preliminary clinical survey of the vasectomized cases through the author's private system and the government subsidy program that the few who told to decrease in sexual capacity and general health were outnumbered by those reporting an increase. The majority of the cases told of no change. The changes noted by a small proportion of patients appeared to be chiefly of psychological origin because there was no physiologic reason why the operation of vasectomy should causes sexual excess or decrease.
Child ; Coitus ; Commerce ; Comprehension ; Financing, Government ; Friends ; Humans ; Interview, Psychological ; Korea ; Male ; Marriage ; MMPI ; Motivation ; Occupations ; Sexual Behavior ; Spouses ; Sterilization ; Sterilization, Reproductive ; Vas Deferens ; Vasectomy*

An anastomosis of the vas deferens was performed on 17 patients since 1963.Semen specimens were examined repeatedly in 15 cases of the series after periods from 2 to 24 weeks following removal of the splint. The fifteen were found to have viable sperm in their ejaculates but one of these patients subsequently became azoospermic again. Three of the fifteen cases had some degree of deteriorated effects after the previous vasectomy but they were free of the complications following the successful anastomosis of the vas deferens. Operative rechnics were discussed. In this series 2-0 dermalon was used as a splint in 15 cases and stainless steel wire was used in 2 cases. Liothyronine was given to 16 of 17 patients at or before the operation for periods from 1 to 6months. Over-all successful results would indicate about 65 per cent of the cases operated in the literature. The author's small series indicates that more than 90 per cent of the operated cases could be successful in this operative procedure from the cytological point of view.
Humans ; Nylons ; Spermatozoa ; Splints ; Stainless Steel ; Surgical Procedures, Operative ; Triiodothyronine ; Vas Deferens* ; Vasectomy*

54-year-old male patient with acute lymphocytic leukemia was consulted to our department. He had had a few painful erythematous necrotic plaques on the chest, which suggested initslly vasculitis or pyoderma. On histological examination, characterisitic histological findings of non-septated large hyphae were observed in the dermis and subcutaneoustissue, Although organism was not isolated on Sabouraud agar media containing cycloheximide, the diagnosis of cutaneous mucormycosis was made by the characteristic histological nattlre. He died after 2 weeks with amphotericin B intravenous injections so that additional fungus culture was not performed.
Agar ; Amphotericin B ; Cycloheximide ; Dermis ; Diagnosis ; Fungi ; Humans ; Hyphae ; Injections, Intravenous ; Male ; Middle Aged ; Mucormycosis* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma* ; Pyoderma ; Thorax ; Vasculitis

BACKGROUND: This study examined the efficacy of patient-controlled epidural analgesia (PCEA) for post-cesarean section pain control and compared the suitability of four different volumes of continuous background infusion (CBI). METHODS: Sixty patients were received 0.125% bupivacaine with 5 g/ml fentanyl by PCEA (2 ml of demand dose and 10 minutes of lockout interval) and CBI. Experimental groups were divided four groups according to the volumes of CBI; 1 ml/hr, 2 ml.hr, 3 ml/hr and 4 ml/hr of CBI during 48 hours postoperatively. RESULTS: Total amount of fentanyl and bupivacaine consumption was significantly higher in 1ml/hr of CBI group than 2 ml/hr of CBI group during first 24 hours, and in 4 ml/hr of CBI group than 1 ml/hr and 3 ml/hr of CBI group during second 24 hours. CBI/maximum hourly demand dose was 15~23%. There is no significant difference between the groups in pain score, side effects and patient's satisfaction. CONCLUSIONS: This study suggests that two or three ml/hr of CBI can provide the most effective postoperative analgesia and the optimal ratio of CBI/maximum hourly demand dose is about 20%.
Analgesia ; Analgesia, Epidural* ; Bupivacaine ; Fentanyl ; Humans

BACKGROUND: In vitro epidermal keratinocytes(EKs) culture systems are widely used in studying skin biology and differentiation. Recently a monolayer culture method of nail matrix cells(NMCs) has been developed. OBJECTIVE: This study was designed to establish a method of culture of NMCs and compared its characteristics with those of EKs. METHODS: Human NMCs were isolated and cultured in a defined medium. Phase contrast microscopic examination, growth rate and ketatin expression were evaluated. RESULTS: In in vitro monolayer culture, NMCs had a similar growth pattern and morphological features as EKs. The synthesis of hard keratins was detected. CONCLUSION: These observations suggest that the NMCs culture model may be useful for the study of nail properties and the effects of drugs.
Biology ; Humans ; In Vitro Techniques ; Methods ; Skin

Nineteen patients (twenty knees) with degenerative arthritis of knee treated by arthroscopic curettage were reviewed. Of the nineteen patients, there were eighteen females and one male ranging in age from 49 to 68 years (mean, 57 years). The mean follow up period was 18.2 months (range, 12 months to 21 months). Simple standing roentgenorgram and 99m-Tc bone scintigraphy were used to select the patients with medial compartment involvement only, less than 5 degree of varus deformity and sparing of patello-femoral joint. Knee scoring by Hospital for Special Surgery Formula showed improvement from the preoperative average 68 points to postoperative average 89.6 points (21.6 points increase) and 84.1 points (16.1 points increase) at 6 months and one year respectively. Arthroscopic curettage of knee, if done early in degenerative arthritis, not only can shorten hospital days and immobilization period but also can defer other major surgical treatments by promoting natural healing process and symptomatic relief.
Congenital Abnormalities ; Curettage ; Female ; Follow-Up Studies ; Humans ; Immobilization ; Joints ; Knee ; Male ; Osteoarthritis ; Radionuclide Imaging

During the period from 1964 to 1958, chemical analyses of urinary calculi were performed on 88 cases treated in the Department of Urology, Seoul National University Hospital. The chemical composition of the calculi analysed is recorded in the following table. COMPOSITION NUMBER OF CASES % OF TOTAL Calcium oxalate 27 30.7 Calcium phosphate 25 28.5 Oxalate & phosphate 17 19.3 Uric acid & phosphate 8 9.1 Uric acid & Oxalate 6 6.8 Uric acid 3 3.4 Carbonate 1 1.1 Carbonate & phosphate 1 1.1 Total 88 100
Calcium ; Calcium Oxalate ; Calculi ; Carbon ; Seoul ; Uric Acid ; Urinary Calculi* ; Urology

No abstract available.
Apnea* ; Doxapram*

Disseminated intravascular coagulation (DIC) is a pathological syndrome in which activation of coagulation cascade leads to fibrin clot formation, consumption of platelets and coagulation factors, and secondary fibrinolysis. We report a case of severe postoperative hemorrhagic diathesis due to DIC. A 59-year-old man was scheduled for reduction of tibia fracture and anatrophic nephrolithotomy of staghorn calculi. On the fifth postoperative day, second operation was performed for nephrectomy due to perirenal hematoma. Two days later, third operation was performed for hemostasis because of the continuous bleeding. Coagulation tests showed positive DIC profiles of thrombocytopenia, hypofibrinogenemia, increased fibrin degradation products, and prolonged prothrombin time and thrombin time. The patient recovered uneventfully and discharged on the 59th postoperative day.
Blood Coagulation Factors ; Calculi ; Dacarbazine ; Disseminated Intravascular Coagulation* ; Fibrin ; Fibrin Fibrinogen Degradation Products ; Fibrinolysis ; Hematoma ; Hemorrhage* ; Hemorrhagic Disorders ; Hemostasis ; Humans ; Middle Aged ; Nephrectomy ; Postoperative Complications ; Prothrombin Time ; Thrombin Time ; Thrombocytopenia ; Tibia