No abstract available.
Tinnitus*

Pyogenic osteomyelitis is a frequent and difficult disease in treatment in orthopedic surgery. The various manifestation of the disease related to the causative organisms, the sites of involvement, the pathogenesis and the clinical course tend to give a bad prognosis after treatment. This study consists of three hundred and twenty four cases of pyogenic osteomyelitis which are studied at the Department of Orthopedic Surgery, Yonsei University hospital for 7 years and 8 months from January 1973 to August 1979. The results are as follows: 1. The frequency of the disease was highest in 1977 but not significant. 2. Femur and tibia were most frequently involved. (65.4%). 3. Age distribution showed the highest incidence between 6 and 15 years of age. (60.6%) Sex ratio was 2(M):1(F) 4. The causative organism was mostly Staphylococcus. (80.5%) The coagulase(+) Staphylococcus showed the highest sensitivity to cefamezine (88.8%) and the highest resistance to penicillin. (89.7%) 5. The treatment had been carried out case by case with variable methods. Author considered the best method of treatment was early decompression and massive antibiotic therapy in acute osteomyelitis, and saucerization with closed irrigation system in chronic osteomyelitis.
Age Distribution ; Cefazolin ; Decompression ; Femur ; Incidence ; Methods ; Orthopedics ; Osteomyelitis ; Penicillins ; Prognosis ; Sex Ratio ; Staphylococcus ; Tibia

BACKGROUND: The concept of preemptive analgesia has been suggested recently as another technique in the treatment of postoperative pain. This study was undertaken to determine whether preoperative blockade of nociceptive input with operative bupivacaine would exert a preemptive effect on postoperative analgesia. METHODS: 40 patients undergoing hysterectomy with general anesthesia were allocated randomly to receive either 0.25% bupivacaine 40ml infiltrated into the proposed wound line 10min before incision or no infiltration. Patient-controlled analgesia fentanyl and ketorolac were administered to both groups during first 48 postoperative hours. RESULTS: Pain scores and cumulative fentanyl and ketorolac consumption dosage at 12, 24, 36, 48 hours after surgery was similar in both groups. CONCLUSIONS: We concluded that preincisional infiltration with bupivacaine had no advantage in reducing postoperative analgesic requirements or pain scores after hysterectomy.
Analgesia ; Analgesia, Patient-Controlled ; Anesthesia, General ; Anesthetics ; Bupivacaine ; Fentanyl ; Humans ; Hysterectomy* ; Ketorolac ; Pain Measurement ; Pain, Postoperative ; Wounds and Injuries

Traditionally, monocular parital oculomotor pareses are localized to the cavernous sinus or retro-orbital region and are usually caused by diabetes mellitus, aneurysms of the internal carotid artery, inflammation by vrial infection or autoimmune diseases, neuropathy or neuromuscular disesases. Although rare, the monocular partial oculomotor paresis also can be caused by lesions of ventral midbrain because of their particular topographic arrangement. We present 2 cases with fascicular oculomotor nerve involvement from midbrain lesion, who presented with monocular partial ocu-lomotor nerve palsy. One patient showed partial ptosis and slow saccadic movement of the right eye. The other patient showed parital ptosis and limitation of adduction and elevation in the left eye. They had normal pupil size and light reflexes. Brain magnetic resonance images showed focal infarction in the fascicular portion of the oculomotor nerve.
Aneurysm ; Autoimmune Diseases ; Brain ; Carotid Artery, Internal ; Cavernous Sinus ; Diabetes Mellitus ; Humans ; Infarction* ; Inflammation ; Mesencephalon* ; Oculomotor Nerve Diseases* ; Oculomotor Nerve* ; Paralysis ; Paresis ; Pupil ; Reflex

Mercury poisoning affects various organs including peripheral and central nervous systems, especially cerebellum. We report a case of mercury intoxication presenting cerebellar ataxia. From several days after exposure to mercury vapor, scanning speech, head titubation, bilateral limb and truncal ataxia developed and progressed slowly. On admission, brain MRI did not show remarkable change. However, nine months later, atrophic changes in both cerebellar hemispheres on follow-up brain MRI and perfusion defects in same areas on brain SPECT were found.
Ataxia ; Brain ; Central Nervous System ; Cerebellar Ataxia* ; Cerebellum ; Extremities ; Follow-Up Studies ; Head ; Magnetic Resonance Imaging ; Mercury Poisoning ; Perfusion ; Poisoning ; Tomography, Emission-Computed, Single-Photon

The c-erbB-2 oncogene encodes a 185,00 dalton transmembrane glycoportein with tyrosine kinase activity, and the aberrant overexpression of which has been implicated in the indution of a malignat phenotype. Overexpression of the c-erbB-2 has been found in many human adenocarcinomas, especially mammarian and ovarian carcinomas, and that is associated with poor prognosis. We used an enzyme-linked immunosorbent assay(ELISA) to explore the relationship between c-erbB-2 oncoprotein and prognostic factors of endmetrial cancer and analyzed the tissued form the 24patients with endometiral cancer and 10 control cases. patinens with endometrial cancer were found to bave 20% of c-erbB-2 oncoprotein overexpression rate and signficiantly higher c-erbB-2 median oncoprotein expression than conterolC-erbB-2 oncoprotein overexpression showed no statistically significant association with known prognostic factors including stage, grade, histologic cell type, myometrial invasion and lymph node metastases, although the c-erbB-2 oncoprotein overexpression rate was increased by stage, and was higher in lymph node metastatic group than in confined to the uterus goup. High c-erbB-2 oncoprotein overexpression was correlated with absence of estrogen receptor (Rs=-0.46, p=0.047) and progestreone receptor (Rs=-0.57, p=0.045), further studies are needed to determine the significance of the c-erbB-2 everexpression in endometrial cancer.
Adenocarcinoma ; Endometrial Neoplasms* ; Estrogens ; Female ; Humans ; Lymph Nodes ; Neoplasm Metastasis ; Oncogenes ; Phenotype ; Prognosis ; Protein-Tyrosine Kinases ; Uterus

The c-erbB-2 oncogene encodes a 185,00 dalton transmembrane glycoportein with tyrosine kinase activity, and the aberrant overexpression of which has been implicated in the indution of a malignat phenotype. Overexpression of the c-erbB-2 has been found in many human adenocarcinomas, especially mammarian and ovarian carcinomas, and that is associated with poor prognosis. We used an enzyme-linked immunosorbent assay(ELISA) to explore the relationship between c-erbB-2 oncoprotein and prognostic factors of endmetrial cancer and analyzed the tissued form the 24patients with endometiral cancer and 10 control cases. patinens with endometrial cancer were found to bave 20% of c-erbB-2 oncoprotein overexpression rate and signficiantly higher c-erbB-2 median oncoprotein expression than conterolC-erbB-2 oncoprotein overexpression showed no statistically significant association with known prognostic factors including stage, grade, histologic cell type, myometrial invasion and lymph node metastases, although the c-erbB-2 oncoprotein overexpression rate was increased by stage, and was higher in lymph node metastatic group than in confined to the uterus goup. High c-erbB-2 oncoprotein overexpression was correlated with absence of estrogen receptor (Rs=-0.46, p=0.047) and progestreone receptor (Rs=-0.57, p=0.045), further studies are needed to determine the significance of the c-erbB-2 everexpression in endometrial cancer.
Adenocarcinoma ; Endometrial Neoplasms* ; Estrogens ; Female ; Humans ; Lymph Nodes ; Neoplasm Metastasis ; Oncogenes ; Phenotype ; Prognosis ; Protein-Tyrosine Kinases ; Uterus

Multiple rice bodies in joints or bursae are rarely encountered in patients with rheumatoid arthritis. Wereport the radiologic findings of massive subacromial bursitis with innumerable rice bodies on the right shoulderof a 38-year-old man with rheumatoid arthritis. Subacromial bursography showed markedly distended bursa withmultiple nodular filling defects. Preconstrast CT scanning revealed well-demarcated hypodense lesion withoutcalcification in subacromio-subdeltoid bursa. Multiple rice bodies showed slightly high signal intensity on T1WIand T2WI, and no enhancement after gadolinium injection.
Adult ; Arthritis, Rheumatoid ; Arthrography ; Bursitis* ; Gadolinium ; Humans ; Joints ; Shoulder ; Synovitis ; Tomography, X-Ray Computed

BACKGROUND: We postulated that ketorolac as a component of surgical site infiltration would result in better analgesia than intravenous ketorolac. METHODS: Sixty patients who scheduled for elective total abdominal hysterectomy received ketorolac 60 mg (2 ml) either via surgical site infiltration directly (n=30) or parenteral route (n=30) with surgical site infiltration of 0.25% bupivacaine 18 ml 20 min before skin incision. RESULTS: Postoperative analgesic requirement, 48 hour total infusion dose and first 12 hour infusion dose of PCA fentanyl, were significantly lower in surgical site group. There were no significant differences in VAS score and side effects between two groups. CONCLUSION: Ketorolac improves analgesia when it is administered in the surgical site.
Administration, Intravenous* ; Analgesia ; Bupivacaine* ; Fentanyl ; Humans ; Hysterectomy ; Ketorolac* ; Passive Cutaneous Anaphylaxis ; Skin

Occipital condyle syndrome, which consists of unilateral occipital region pain associated with ipsilateral 12th cranial nerve paresis, is a rare, but stereotypic syndrome. Herein, we report a patient with occipital condyle syndrome associated with metastasis at the skull base from the hepatocellular carcinoma.
Carcinoma, Hepatocellular* ; Cranial Nerves ; Humans ; Hypoglossal Nerve Diseases ; Neoplasm Metastasis ; Paresis ; Skull Base