1.Relationship between the functional integrity of human sperm membrane and seminal parameters
Hang GUO ; Haizheng ZHENG ; Ruixue WANG ; Ruizhi LIU
Basic & Clinical Medicine 2006;0(01):-
Objective To study the relation between function of sperm membrane and seminal parameters.Methods Five hundred and three semen samples were collected from 149 normal men and 354 infertile men.Sperm concentration,motility,viability,semen WBC concentration,morphology and sperm tail hypo-osmotic swelling(HOS) were analyzed according to WHO criteria. Results Sperm HOS score in infertile group was lower than that in control group(P
2.Research progress on sex-hormone-like effects of epimedium
Haizheng WANG ; Qi ZHANG ; Wen CHEN ; Xiangguang YANG ; Fei CHEN ; Wei ZHUANG ; Li ZHU
International Journal of Traditional Chinese Medicine 2022;44(4):465-468
Epimedii folium is a commonly used Traditional Chinese Medicine (TCM) for warming the kidney and strengthening the yang qi. It has androgen-estrogen-like effect. It can not only directly act on sexual organs to regulate hormone levels, but also exert sex-hormone-like effect through hypothalamus-pituitary-gonadal axis. Its regulation of hormone levels is similar to that of plant hormones. At present, Epimedii folium is commonly used with other TCMs to treat diseases caused by sex-hormone deficiency, such as male spermatopenia, asthenospermia, benign prostatic hyperplasia, functional erectile dysfunction, female premature ovarian failure, perimenopausal syndrome, dysfunctional infertility during ovulation, hyperandrogenemia of PCOS patients, etc.
3.Establishment and practice of joint consultation mode between TCM physicians and TCM clinical pharmacists in our hospital
Fei CHEN ; Qian WANG ; Haizheng WANG ; Xiaolan LIN ; Wei ZHUANG
China Pharmacy 2024;35(15):1905-1909
OBJECTIVE To provide a reference for medical institutions in selecting and establishing a traditional Chinese medicine (TCM) clinical pharmaceutical care mode that suits their clinical characteristics. METHODS Combining clinical cases, this paper introduces the workflow and service content of the joint consultation mode between TCM physicians and TCM clinical pharmacists in our hospital and analyzes its effectiveness. RESULTS The workflow of the pharmaceutical care mode in our hospital involves six stages:assessing the patient’s medication status, consultation rounds and formulating medication regimen, bedside education, pharmaceutical monitoring, pharmacist rounds, and extended pharmaceutical care. The care content primarily includes thoroughly collecting clinical information and evaluating the patient’s medication regimen before the consultation. During the consultation, TCM clinical pharmacists and TCM physicians jointly developed a dosage regimen tailored to the patient’s individual conditions. After the consultation, bedside medication education was conducted to ensure the correct use of medications and a pharmaceutical monitoring plan was developed and implemented, during which the patient’s post-consultation condition changes were monitored and timely feedback to the TCM physicians for medication plan adjustments was provided, offering extended pharmaceutical care post-consultation, including medication consultation, pharmaceutical outpatient services, and joint clinics. Since its implementation, nearly 1 000 inpatients have been served annually, with a 100% medical order review rate for patients taking TCM decoction pieces. Individualized medication education reached 78.80%, and patient’s degree of satisfaction was 100%. The prescription compliance rate of TCM decoction pieces in the wards increased from 89.33% before the implementation of the joint consultation to 97.08% afterward. Additionally, the mode provided TCM-related consultations to over 1 000 patients annually and compiled and provided nearly a hundred pharmaceutical documents to healthcare personnel. CONCLUSIONS By establishing the joint consultation mode between TCM physicians and TCM clinical pharmacists and conducting TCM clinicalpharmaceutical care, the level of rational use of TCMdecoction pieces has been promoted, demonstrating the value of TCM clinical pharmacists.