Objective To compare the effect of the application of tracheal intubation with SEESHEEN video intubation endoscope (ENF-20) and direct laryngoscopy in patients with missing teeth.Methods 50 patients with missing teeth were selected,and they were randomly divided into two groups, respectively after induction of general anesthesia in tracheal intubation using ENF-20 (group E) and direct laryngoscopy (SHUCMAN laryngoscopy) (group S) intubation.The time of intubation, the times of intubation and the complication of intubation were recorded.Results The success rate of intubation in group E was 92%, which was significantly higher than 64% in group S (x2=5.711,P=0.017).The intubation time of group E was (27±12)s, which was significantly shorter than (36±13)s in group S (t=-2.620,P=0.012).The total intubation complications of group E was 12%, which was significantly lower than 48% of the group S (x2=6.095,P=0.014).Conclusion The successful rate of tracheal intubation in patients with missing teeth by using video tracheal intubation (ENF-20) is higher and with less complication.

While the development and application of gene technology are benefiting human beings widely and deeply, it also arouses people's special attention towards the sustaining of human value and dignity. Ethic problems caused by gene diagnosis, gene treatment and the interpretation of human genome code allow no ignorance. It is an important researching subject in the 21th century to conduct scientific ethical education to personnel of gene technology and medical students according to correct ethic education principles, so as to avoid or reduce the damage caused by it as much as possible.

The primary immunotherapy for gastric cancer includes cytokine therapy,monoclonal antibody therapy, and cancer vaccines. A lot of researches are being conducted to study gene immunotherapy. It has found that Cbl-b gene plays an important role in regulating anti-tumor immunity and Cbl-b protein is involved in the lymph node metastasis of gastric cancer. Silencing Cbl-b gene in T lymphocytes can enhance anti-tumor immunity,therefore may become an effective treatment for patients with advanced gastric cancer.

Objective:To verify the applicability of Dynamic Contrast Enhanced Magnetic Resonance Imaging(DCE-MRI)to evaluate the breast cancer therapy using the high intensity focused uhrasound(HIFU).Methods:Both DCE-MRI and conventional T_1W/T_2W images were acquired for the total 8 subjects.Two consecutive scans were performed for every patient(before operation and 2 weeks after operation)while four were performed for only 2 patients(additional for 6 months and 12 months after operation).The breast cancer therapy by HIFU was assessed hy comparing the changes of signal,the dynamic patterns of time-signal intensity curve,the early-phase contrast enhancement ratios and vessel anatomies around cancer focuses.Results: The shortened T_2 signals were observed in cancer focuses of 5 subjects while 3 still showed longer T_2 values which were differentiated by the high intensity in T_2W images.The early-phase contrast enhancement ratios of those 5 subjects decreased from 60%～80% to

Objective To analyse the reason of gastrointestinal hemorrhage,and the relationship between the degree of fever and the quantity of hemorrhage and blood transfusion volume.Methods The patients suffering from the gastrointestinal hemorrhage were selected from the Central Hospital of Xinyang from June 1996 to June 2005. The treatment of 225 patients were analysed.Results The symptoms of fever arose.The number of higher fever ex- ceeding 39.0℃was 16 accounting for 7.1%.The number of secondary fever was 82 numbers,accounting for 36.4%.The number of lower fever (37.3～38.1℃) was 127,accounting for 56.4 %.Conclusion The degree of fever have a remarkable relationship with gastrointestinal hemorrhage and transfusion.Patients with large quantity of hemorrhage and blood transfusion volume usually have a high degree of fever.

Objective To study the significance of combined detection of lung resistance protein(LRP),P-glycoprotein(P-gp),glutathione S-transferace-?(GST-?) and topoisomeraseⅡ(TopoⅡ) in gastric cancer prognosis judgment.Methods One hundred and thirty-six patients with human gastric carcinomas were studied for the expression of LRP,P-gp,GST-?and TopoⅡ by using immunohistochemistry.Results There were significant relationships in the positive expression rate of LRP,P-gp,GST-?between high-Medium differentiated adenocarcinoma and Poorly differentiated adenocarcinoma,Mucinous carcinoma,and Undifferentiated carcinoma(P

Objective:To study the dynamic distribution of BaP in the corpus striatum by r-counting and light microscopic autoradiography,then to explore the neurotoxic mechanism of BaP.Methods:100 SD male rats were divided into control group(n=40)and test group(n=60),experimental animals were given a single intravenous injection of 3.7?105 Bq/kg of 14CBaP while the same doses of Normal Saline were given to the control group.The rats were sacrificed at 1h,1 d,2 d,3 d and 7 d after the administration of radiolabelled BaP.During the experiment,some toxicological symptoms were observed and the ratios of brain-weight/body-weight were detected.Light microscopic autoradiography and r-counting were used to observe the dynamic distribution of BaP in the corpus striatum.Results:The change of toxicological symptoms are observed and the decrease ratios of brain-weight/body-weight are detected.R-counting shows that the percentage dose/g of 14CBaP in striatum is significant higher than in hippocampus and cortex at 1d and 2 d after administration.Light microscopic autoradiography shows that the silver granules in striatum reach the peak in 1d and sharp decrease in 2 d,which can be found even at 7d.Conclusion:BaP can penetrate the blood-brain barrier and distribute in corpus striatum,inducing CNS toxicity in SD rat.

15?109 had statistical difference. The same difference was found with group of N

Investigation on anti-HCV in different cohorts of 21844 blood donors from 18 districts and counties of Beijing, and Guan, Yongqing, Xincheng, Xushui counties of Hebei province had been performed. It was showed that the anti-HCV-positive rates of voluntary and nonpaid donors were 1.7% (13/738) and 2.9% (116/3943) respectively, and 13. 6% (2011/14757)and 48.1% (1161/2415) for paid donors and plasma pheresis donors respectively. It was also found that the anti-HCV-positive rates of paid donors from Guan and Yongqing counties were (16.4%82/499) and 13.9% (53/381) respectively, 50% (575/1148) and 56% (540/965) for plasma pheresis donors from those counties respectively. The positive rates increased with the level of ALT. More than 45.5% donors whose ALT was above 45 U had anti-HCV.

The methods of extraction of purified blood mononuclear cell(PBMC)from human bully coat (BC), and the conditions of serial production of high titer IL-2 by using PBMC as raw material were studied. For separation of PBMC was selected Methyl Cellulose-Ficoll Hypaque (MC-FH) which can not only be suited to its serial production but also ensure its quality. The separated PBMC's viability was more than 95%, and the phagocyte contamination was less than 5%. The combined PHA/TPA induction method was selected by investigating the various induction methods and conditions. The conditions for inducing the IL-2 by TPA/PHA method were as following., the PBMC's concentration had better be 1.25～2.5?10~6ml; 5% of normal human AB serum was substituted for calf serum; domestic universal microorganism culture kit was used instead of imported CO_2 culture kit: culture was conduced in the rotating 500ml sealed bottles at 37℃ for 72～96 hours. The titer of IL-2 produced under mentioned above conditions reached four digits, and its highest value was 2100 IU/ml and was 20 times higher than that of the titer of IL-2 induced by PHA method. The yield of IL-2 induced with 20units of buffy coat(from 4000ml whole blood) was 23?10~6IU, and the resulting amount of induced liquid was 2000～3600ml. This provided a suitable technological process for production of IL-2 using the buffy coat as raw meterial. (Original article on page 1)