Abdomen ; anatomy & histology ; Acupuncture Points ; Acupuncture Therapy ; Adult ; Combined Modality Therapy ; Drugs, Chinese Herbal ; administration & dosage ; Female ; Humans ; Leiomyoma ; therapy ; Middle Aged

Objective To explore the difference of efficacy between LEEP and microwave treatment on chronic cervicitis.Methods According to the different treatment method,400 patients with chronic cervicitis were divided into LEEP group (LEEP treatment) and microwave group (microwave treatment),each group 200 cases.The treatment time,amount of bleeding and the healing effect between the two groups were compared and analyzed.Results The operative time,amount of bleeding before and after operation,vaginal fluid time after surgery of LEEP group were (6.94 ± 1.13) min,(2.13 ± 0.32) ml,(15.23 ± 3.40) mi,(7.06 ± 1.47) d,which were better than those of the microwave group[(16.13 ± 2.81) main,(5.94 ± 1.45) ml,(50.06 ± 7.86) ml,(17.58 ± 4.33) d] (t =42.91、36.29、57.52、32.54,all P ＜ 0.05).The number of recovery patients had no statistically significant differences in mild,moderate patients of the two groups(97 cases vs 104 cases and 54 cases vs 45 cases,χ2 =0.81,1.35,all P ＞0.05),and the number of recovery patients in the LEEP group was better than that in the microwave group(23 cases vsl4 cases,χ2=6.87,P ＜ 0.05).Conclusion The efficacy of LEEP knife on chronic cervicitis was significantly.It has a less operative time,less blood loss,better recovery.It is worthy of promotion.

Objective To observe the clinical efficacy of moxibustion in treating primary dysmenorrhea in adolescent female undergraduates. Method Sixty patients with primary dysmenorrhea were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by moxibustion at Guanyuan (CV 4), while the control group was by moxibustion at Sanyinjiao (SP 6). The symptom score was observed before intervention and after 3 menstrual cycles, and the clinical efficacies were compared. Result The symptom score was changed significantly in both groups after intervention (P<0.01). After intervention, there was a significant difference in comparing the symptom score (P<0.05). The total effective rate was 100.0%in the treatment group versus 93.3% in the control group, and the difference was statistically insignificant (P>0.05). Conclusion Moxibustion is an effective approach in treating primary dysmenorrhea, and moxibustion at different points will produce different effects.

BACKGROUND:Several studies have confirmed that bone marrow mesenchymal stem celltransplantation exerts a certain neuroprotective role in cerebral infarction. Edaravone is a novel potent smal-molecule hydroxyl radical scavenger, which play a protective role in the brain by eliminating free radicals and inhibiting nerve celldamage after cerebral infarction. OBJECTIVE:To explore the influence of bone marrow mesenchymal stem cells combined with edaravone on expressions of aquaporin-4, Bcl-2, and brain-derived neurotrophic factor after cerebral infarction in rats. METHODS:Eighty Wistar rats were selected to establish models of cerebral infarction by right middle cerebral artery occlusion, and then randomly divided into control group, bone marrow mesenchymal stem cells group, edaravone group and edaravone+bone marrow mesenchymal stem cells group (combination group). After 6 hours of modeling, rats from these four groups were respectively injected via the tail vein with PBS, bone marrow mesenchymal stem cells, edaravone and edaravone+bone marrow mesenchymal stem cells. After 72 hours, the rats were decapitated to take brain tissues. Consequently, expressions of aquaporin-4, Bcl-2, and brain-derived neurotrophic factor mRNA and protein were determined by RT-PCR and western blot methods. After 12, 24 and 36 hours, TUNEL method was used for the determination of cellapoptosis. RESULTS AND CONCLUSION:The expressions of Bcl-2 and brain-derived neurotrophic factor were higher in the combination group than the other three groups (P<0.05), but the expression of aquaporin-4 was lowest in the combination group (P<0.05). The number of apoptotic cells in the combination group was significantly lower than that in the other three groups. These findings suggest that the combination of bone marrow mesenchymal stem cells and edaravone can improve expressions of Bcl-2 and brain-derived neurotrophic factor in the injured site, and significantly inhibit neuronal apoptosis. Meanwhile, the combination therapy can decrease expression of aquaporin-4 and mitigate cerebral edema, which is superior to bone marrow mesenchymal stem celltransplantation and edaravone alone.

Objective To understand the epidemic situation of common human soil-transmitted nematode infections in Quan-zhou City in 2012,so as to provide the evidence for improving the prevention and control measures. Methods The residents aged above 3 years from 5 townships in 2 counties were investigated to detect the parasite eggs(hookworm,Ascaris lumbricoides,Trich-uris trichura)by Kato-Katz technique. One kindergarten of each county was randomly selected and 228 children were investigated to detect Enterubius vermicularis eggs by the cellophane tape anus test. Results The total hookworm infection rate was 3.60%(69/1919). For the hookworm infection rates,there was no significant difference among different areas and between different genders, but there were significant differences among different age groups and different careers. No Enterubius vermicularis eggs were detect-ed. Conclusion The effect of the prevention and control of Ascaris lumbricoides,Trichuris trichura and Enterubius vermicularis in-fections is remarkable. However,the infection rate of hookworm has a rising trend and the prevention and control of hookworm in-fection should be strengthened.

Objective To explore the risk management factors and preventive measures in obstetric care. Methods The implementation of risk management in our hospital was retrospectively analyzed. Results Maternal satisfaction degree was significantly increased, complaints and errors of nursing care were significantly decreased. Conclusions Strengthening of risk management in obstetric care can benefit to eliminate and prevent unsafe factors, so that obstetric care quality is improved.

The primary immunotherapy for gastric cancer includes cytokine therapy,monoclonal antibody therapy, and cancer vaccines. A lot of researches are being conducted to study gene immunotherapy. It has found that Cbl-b gene plays an important role in regulating anti-tumor immunity and Cbl-b protein is involved in the lymph node metastasis of gastric cancer. Silencing Cbl-b gene in T lymphocytes can enhance anti-tumor immunity,therefore may become an effective treatment for patients with advanced gastric cancer.

Objective To investigate application of local anesthesia on the success rate of PICC. Methods A retrospective analysis was carried out in patients (120 cases)receiving PICC from March 2004 to January 2006. Randomly selected 120 cases were divided into 2 groups, each with 60 cases and PICC was im-plemented with the conventional method or under local anesthesia respectively in the two groups. Psychological changes of patients and nurses,adverse reactions of pain, success rate and incidence rate of complications were observed. Results The two groups were different in the following aspect, success rate, psychological changes, adverse reactions of pain,etc (P<0.01). Conclusions Local anesthesia during PICC is conducive to raise the success rate of tube insertion and the elimination of other adverse factors, especially for coarse PICC suite.

Vascular stenosis can mainly be divided into two types:the congenital vascular stenosis and acquired vascular stenosis.The etiology of congenital vascular stenosis is unclear yet,it usually occurred in different types of congenital cardiovascular and cerebrovascular stenosis.Acqnired vascular stenosis is often caused by athemsclerotic plaque,resulting in the percutaneous brace implantation,or balloon angioplasty.Imaging methods can be helpful in the clinical diagnosis and evaluation of various congenital or acquired vascular stenosis accurately and timely.Currently,imaging technology has developed rapidly and the new imaging technology emerges.This paper briefly reviews the imaging technology progress in evaluating the vascular stenosis.

Highly developed molecular genetic techniques have got implemented widely in the diagnosis of birth defects and genetic diseases.Due to the special nature of genetic testing , there is still a lack of appropriate external quality assessment , but many clinical laboratories are conducting or going to conduct genetic diagnosis for monogenic diseases and prenatal diagnosis.In this paper , it will be discussed that how to ensure the quality control of the laboratory diagnosis of monogenetic diseases , based on the present application of genetic testing technologies and the difficulties in the diagnosis of monogenetic diseases.