1.Transition care from paediatric of chronic diseases to adult
International Journal of Pediatrics 2012;39(3):258-261
Transition care is the important conditioin,which helps children of chronic diseases enter from paediatrc care to adult care.At present,transtion care has become a hot topic overseas,but it hasn't been thought seriously in China.Now this paper reviews the causes,essential aspects and current situation of transition care,as well as its assignments to patients,parents,doctors and hospitals respectively.
2.Clinical research of acute posterior ganglionitis with the glycuresis
Chinese Journal of Primary Medicine and Pharmacy 2011;18(6):778-779
Objective To investigate the curative effect of acute posterior ganglionitis with the glycuresis. Methods Retrospectively analyzed the clinical data of the observation group and control group patients,compared the curative effect of the two groups and the different blood sugar concentration of the observation group. Results After one course of treatment,the cure rate and total effective rate of the control group were all higher than the observation group. The total effective rate of the patients with good blood sugar controlling was higher than the patients with bad blood sugar controlling. Conclusion Glycuresis affected the curative effect of acute posterior ganglionitis treating seriously, and had concern with the blood sugar controlling, for the patients of acute posterior ganglionitis with the glycuresis , the blood sugar should be controlled positively in order to improve the curative effect.
3.Resveratrol and cancer metastasis
Journal of International Oncology 2012;39(7):508-509
Resveratrol is a natural phytoalexins.In vivo aud vitro experiments show that resveratrol could inhibit tumor metastasis by multiple approaches,such as influencing the expression level of matrix metalloproteinases and inhibitors,inhibiting tumor angiogenesis and interferencing signaling pathways,et al.
4.Demineralized bone matrix as a bone tissue engineering scaffold material
Chinese Journal of Tissue Engineering Research 2014;(3):426-431
BACKGROUND:Demineralized bone matrix as bone tissue engineering biological scaffold material is more researched currently, which has osteoinductive and osteoconductive.
OBTECTIVE:To summarize the development of demineralized bone matrix as bone tissue engineering scaffold material and to prospect its trend.
METHODS:The relative literatures addressing demineralized bone matrix as bone tissue engineering scaffold material published between January 1965 and May 2013 in PubMed database, Chinese Biomedical Database, Wanfang Database and FMJS database were searched by the first author. The key words were“demineralized bone matrix, scaffold material, growth factor, cells, drugs”in English and Chinese. According to the inclusion criteria, repetitive researches were excluded, and final y 34 articles were included.
RESULTS AND CONCLUSION:Scaffold material is the key composition of tissue engineered bone, and only demineralized bone matrix has both osteoinductive and osteoconductive properties which cannot only provide space for bone repair, but also can be combined with bioactive factors, living cells, antibiotics in vitro to construct bone graft thereby promoting healing of bone defects. However, this technique is also facing some problems to be solved such as the ratio of demineralized bone matrix and various substances, disinfection, preservation of osteogenetic activity and antigenicity elimination. Sufficiently understanding demineralized bone matrix as bone tissue engineering scaffold can provide a theoretical basis for its clinical service.
7.Study of pharyngeal bacterial pathogens of community acquired pneumonia of 359 children
Yan HUANG ; Haixia CHEN ; Zhenze CUI
Chinese Journal of Postgraduates of Medicine 2010;33(6):26-28
Objective To investigate the pharyngeal bacterial pathogens of children's community acquired pneumonia(CAP)in hospital,and provide evidences to clinical empirical therapy.Methods Three hundred and fifty-nine patients with CAP were selected.Before the treatment,pharyngeal swabs was taken for culture to find bacteria,then to be done drug sensitivity quantitative test and examed the extended spectrum β lactamages(ESBLs).Results The positive rate was 21.7%(78/359)and bacteria was 82 strains.It was mainly consisted with gram negative bacteria(73.2%,60/82),and klebsiella pneumonia (30.5%,25/82).Streptococcus pneumonia(18.3%,15/82)was the most common in gram positive bacteria.Klebsiella pneumonia was resistant to amoxicillin.Drug resistance of ESBLs producing strains was increased.Streptococcus pneumonia was highly resistant to erythromycin,clindamycin,and tetracycline.The ratio of bacteria infection in infancy age(34.6%.47/136)was higher than others.Conclusions Gram negative bacteria is significant pharyngeal bacterial pathogens in CAP of children.The most common ono is klebsiella pneumonia,and the corresponding one in gram positive bacteria is streptococcus pneumonia.Clinical doctors should avoid using high antibiotic-resistance drugs.
8.A Study of Viral Pathogens In 280 Cases of Children with Community Acquired Pneumonia (CAP)
Haixia CHEN ; Yan HUANG ; Zhenze CUI
Journal of Medical Research 2009;38(8):73-75
Objective To investigate the viral pathogens of children with community acquired pneumonia (CAP) in dalian city dur-ing the last year in hospital ,and provide evidences to clinical empirical therapy. Methods Some patients of department of respiratory, in Dalian children' s hospital were derided into four groups from May 2007 to 2008. Serum virus antibodies were detected after 1 week of nat-ural course of disease. Results In 280 cases who were detected for viral lgM antibodies, the positive rate was 28.2%. It was mainly con-sist with respiratory syncytial virus, adenovirus, and parainfluenza virus. The ratio of virus infection in school age group (54.0%) was higher than that in other groups. The second is in toddler age. Conclusion Virus are significant pathogens in CAP of children. The most common viral agent is respiratory syncytial virus (RSV), and the next one is adenovirus (ADV). The ratio of virus infection in school age group is the highest. We should give anti - virus and propotional supportive treatment to these children promptly.
9.Study on Pharmacognosy of Chongqing Local Medicinal Material Heracleum hemsleyanum
Haixia FENG ; Yanhong SHI ; Shaocheng CHEN
China Pharmacy 2015;26(36):5136-5138
OBJECTIVE:To establish a method for the identification of Chongqing local medicinal material Heracleum hemsley-anum. METHODS:The original plant morphology,morphological characteristics,microscopic characteristics (transverse section and powder),were identified. RESULTS:H. hemsleyanum had cone shape root,brown,many-branched with special fragrance;the microscopic characteristics of taproot a transverse showed no differences with lateral root transverse section,primary xylem was di-arch,secondary phloem was more developed than secondary xylem,secondary phloem was rich in the oil chamber. Vascular tissues contained a large number of parenchyma cells. In TLC chromatrogram,the test sample showed the same color fluorescent spots with-the substance reference of osthole and columbianadin in the corresponding locations. CONCLUSIONS:The established method is simple with high accuracy,and can be used as the basis for identification of H. hemsleyanum.