Objective: To know the situation of college students to grasp knowledge about generation health in Xi'an and to help the department to give an aimed education. Methods: 1020 students were investigated by questionnaire and the data be analyzed by the software Epi5.0. Result: College students' knowledge about generation health and STDs were very little. About 1/3 of them didn't know how to make urgent contraception, however the proportion of abortion were so high in university. Conclusion: The education of knowledge about generation health and guidance about contraception should be strengthened in university, especially in freshmen.