1.Surgical traction machine for physical therapy controlled by single-chip microcomputer
Chinese Medical Equipment Journal 1989;0(02):-
This paper describes a kind of surgical traction machine for physical therapy, which adopts closed loop control mode and a single-chip microcomputer as the control unit. Input can be accomplished through the keyboard or mechanical sensor. Traction is fulfilled through an electromotor-driven mechanism. Inputted parameters and running status can be displayed simultaneously. Being convenient and reliable, the machine can be applied to treatments of cervical spondylosis and lumbar one.
2."Ethical Consideration on the Researches Using Human Biological Specimen-Revision Suggestion and Enlightenment of ""Common Rule"" for Subject Protection in the United States"
Chinese Medical Ethics 2016;29(5):849-851
The use of human biological specimen has great significance to the development of biomedicine. Meanwhile, the powerful electronic data set with sophisticated analytic techniques creates challenge to the protec-tion of private information. As for the research with human biological specimen, how to facilitate the research con-duct on the basis of ethical principles is one of the key considerations when the US Department of Health and Hu-man Service initiated the revision of Code of Federal Regulations ( CFR) -theCommon Rule for subject protec-tion. The Notice of Proposed Rulemaking ( NPRM) proposed:Respect for autonomy will be enforced by broad con-sent to enforce and waiver of consent intend to be rare;If the research risks only involve privacy protection, review process will be simplified under the premise of ensuring the implementation of privacy laws and other protective measures. The paper introduced the revisions related to the researches using human biological specimen in NPRM, analyzed the terms of broad consent, exemption and exclusion, and explored the elicitation to ethical review prac-tice in China.
3.Clinical Observation of Yangyin Tongluo Pills Combined with Acupuncture for Treatment of Cerebral Infarction Sequela
Haitao LIU ; Bo WANG ; Dexi LIU
Journal of Guangzhou University of Traditional Chinese Medicine 2015;(1):23-26
Objective To observe the clinical effect of Yangyin Tongluo Pills combined with acupuncture for the treatment of cerebral infarction sequela. Methods One hundred patients with cerebral infarction sequela were evenly randomized into treatment group and control group. The control group was given acupuncture therapy combined with oral use of clopidogrel, and the treatment group was given acupuncture therapy combined with oral use of Yangyin Tongluo Pills (mainly composed of Fructus Lycii, Flos Chrysanthemi, Radix Rehmanniae, Cortex Moutan, Radix Salviae Miltiorrhizae, Flos Carthami, Semen Persicae, Pheretima, Rhizoma Gastrodiae, Ramulus Uncariae cum Uncis, Spica Prunellae, Radix Glehniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Pseudostellariae) . One month constituted a treatment course, and the treatment covered 2 courses. After treatment, the therapeutic effect of the two groups was evaluated, and the changes of National Institute of Health Stroke Scale ( NIHSS) scores and Barthel Index Scale for activities of daily living ( ADL) , and hemorrheology indexes were observed before and after treatment. Results (1) After treatment for 2 courses, NIHSS scores were decreased, ADL scores were increased in the two groups (P<0.01 compared with those before treatment) , and the improvement of the treatment group was superior to that of the control group ( P<0.01) . ( 2) After treatment, hemorrheology indexes were much improved in the treatment group ( P<0 . 05 or P<0 . 01 ) , but remained unchanged in the control group ( P>0.05) . The treatment group had better effect on improving hemorrheology indexes than the control group (P<0.05) . (3) The total effective rate of the treatment group was 90.00% and that of the control group was 64.00%, the overall therapeutic effect of the treatment group being superior to that of the control group (P<0.05) . Conclusion Yangyin Tongluo Pills combined with acupuncture are effective for the treatment of cerebral infarction sequela, and the effect is superior to that of acupuncture combined with clopidogrel.
4.Overlapping syndrome of antibody-related autoimmune encephalitis
Bin LIU ; Haitao REN ; Hongzhi GUAN
Chinese Journal of Neurology 2021;54(1):71-74
With the understanding of autoimmune encephalitis many novel types of autoimmune encephalitis and related antibodies have been identified. There are some cases of autoimmune encephalitis with autoantibody overlapping syndromes or phenotype overlapping syndromes, which bring challenges to diagnosis and treatment in practice. The relevant literature was reviewed and the clinical characteristics, pathological mechanism and treatment of overlapping syndromes associated with autoimmune encephalitis were summarized, in order to provide a reference for the management of autoimmune encephalitis with overlapping syndromes.
5.Studies on the Chemical Constituents of Alseodaphne hainanensis
Haitao CHANG ; Lian LIU ; Pengfei TU
Chinese Traditional and Herbal Drugs 2000;31(10):725-727
Four compounds were isolated from the ethanolic extract of the bark of Alseodaphnehainanensis Merr. , The structures were identified as: a neolignan eusiderin A [(7R, 8R)-3,4,5,3′-tetram-ethox-△8’,9’-8-o-4’,7-o-5’lignan](I)two benzylisoquinoline alkaloids (6,7-dimethoxyisoquinolinyl)-(4′-methoxyphenyl) methanone(Ⅱ), and( 6, 7-methylenedioxyisoquinolinyl )-( 4′-methoxyphenyl ) methanone (Ⅲ), and 4-hydroxy-3-methoxy benzoic acid ( Ⅳ ) on the basis of HR-SIMS,1HNMR,13CNMRand 2D-NMR spectroscopic analysis. CompoundsⅠ~Ⅲ were obtained from the Alseodaphne genus forthe first time.
6.The effect of bispecific antibody(BsAb,anti-human bladder cancer/anti-VEGF) on cancer bearing mice
Ming REN ; Lucheng LIU ; Haitao FAN
Chinese Journal of Immunology 1999;0(12):-
Objective:To study the inhibitory role of BsAb(anti-human bladder cancer/anti-VEGF) on human bladder cancer growth.Methods:BsAb was used to treat animal models of BIU-87 cell lines.The tumor inhibition rate was calculated and the tumor microvessel density was detected by immunohistochemical techniques.Results:BsAb could significantly inhibit growth of tumor.And the tumor microvessel density was lower than that of the control group.Conclusion:BsAb could inhibit tumor growth by inhibiting angiogenesis. BsAb may become a new method for human bladder cancer treatment.
7.Clinical comparison of tacrolimus and CsA in end stage renal disease of diabetic renal allograft recipients
Lixin YU ; Haitao SAN ; Xiaoyou LIU
Chinese Journal of Organ Transplantation 2003;0(06):-
0.05 ) with the CsA group ( 28.15 ? 8.33 )U/d, ( 13.05 ? 2.17 )U/d at the first month and 1 year after the operation. One year after the operation, 21 patients ( 63.63 %) were subjected to anti-hypertensiom, 5 patients ( 15.15 %) to anti-hyperlipidemia treatment and 3 patients ( 9.09 %) to liver protection treatment due to abnormal liver function in FK506 group, while in the CsA group 28 patients ( 90.32 %) were subjected to anti-hypertension, 13 patients ( 41.94 %) to anti-hyperlipidemia treatment and 11 patients ( 35.48 %) to liver protection treatment due to abnormal liver function. There were significant differences between the two groups.Conclusion The small dose low concentration FK506 is effective in the end stage renal disease of diabetic renal allograft recipients and side effect incidence of it was low, and it has almost the same influence on the glucose metabolism as the CsA.
8.Evaluation of the effects of low-dose ketamine on postoperative analgesia
Haitao ZHAO ; Huirong CHEN ; Yonqin LIU
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
Objective To investigate the effects of low-dose ketamine combined with fentanyl or sulfentanyl in postoperative patient-controlled intravenous analgesia.Methods Two hundred cases with ASA Ⅰ~Ⅱ undergoing elective orthopedic operations were randomly allocated into four groups(50 cases for each group): 0.4?g/(kg?h) fentanyl(group F);0.2?g/(kg?h) fentanyl+120?g/(kg?h) ketamine(group FK);0.04?g/(kg?h) sulfentanyl(group S);and 0.02?g/(kg?h) sulfentanyl+120 ?g/(kg?h) ketamine(group SK).8mg of ondansetron was added to each recipe,and then diluted into 100ml with normal saline.The loading doses of all the patient-controlled-analgesics were 2ml administered 30min before the end of the operation.The background infusion doses were 2ml/h,while the pressing doses were 2ml,with intervals of 30min.Heart rate(HR),blood pressure(BP),respiration rate(RR),pulse O2 saturation and visual analogue scales(VAS),sedation score(SS) with adverse effects and the total times of pressing PCA pump button were observed and recorded in all patients respectively for 48h after operations.Results No statistically significant differences were found in HR,BP and RR among the four groups.VAS and the total pressing times in group F were higher than that in the other groups significantly(P
9.Influence of different combination of anesthetics on BP and HR during operation in aged patients with serious illness
Yongqin LIU ; Wei WANG ; Haitao ZHAO
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
Objective To evaluate the influence of different combination of anesthetics on blood pressure (BP) and heart rate (HR) of aged patients with serious illness during operation. Methods Forty patients, aged 80~92, with physical status Ⅱ~Ⅲ as categorized according to American Society of Anesthesiologists (ASA) undergoing selective surgery, were randomly divided equally into two groups: in group A ancsthesia was induced with midazolam, fentanyl and maintained with isoflurane, and in group B anesthesia was induced and maintained with etomidate, sevoflurane and nitrous oxide. Mean arterial pressure (MAP), HR and bispectral index (BIS) were observed at the points of preinduction (T0), induction (T1), intubation (T2), incision (T3), 30 minutes after incision (T4) and extubation (T5). Results After induction, BIS decreased from 95?2 to 52?4, while MAP and HR decreased from 110?11mmHg and 73?8/min to 75?9mmHg and 59?4/min respectively, in group A. While in group B BIS decreased from 94?3 to 58?3, MAP and HR decreased from 103?8 mmHg and 76?6/min to 87?7 mmHg and 67?5/min, respectively. At the point of tracheal intubation, MAP and HR increased significantly in group A compared with group B (P
10.Clinical Observation of Jianpi Yishen Granule in the Relief for Toxic and Negative Effects of Chemotherapy in Treating 528 Cases of Cancer
Haitao DONG ; Hao LIU ; Nianbo GUAN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(09):-
Objective To observe the clinical effects of Jianpi Yishen granule in the relief for toxic and negative effects of chemotherapy in treating cancer.Methods Five hundred and twenty eight cases were randomized into two groups:the treatment group in which Jianpi Yishen granule and chemotherapy were used and the control group in which chemotherapy only was given.Total two cycles were performed for two groups.The effective rate,the changes of Karnofsky scores and immunity,the adverse reaction to chemotherapy in the two groups were observed before and after the treatment.Results The effective rate (CR+PR) in the treatment group and the control group was 61.4% and 60.5% respectively,and the improvement in Karnofsky scores in the fomer was higher than in the latter (P