Objective: To investigate the effects of the link between overweight/obesity and type 2 diabetes mellitus (T2DM) on leptin and visfatin levels. Methods: Males without T2DM and male patients with T2DM hospitalized in Lishui Municipal Central Hospital from January to June, 2017 were enrolled. Subjects' age and medical history of diseases were collected. The height and body weight were measured, and the body mass index (BMI) was estimated. The leptin and visfatin levels were determined, and compared between patients with and without T2DM, and between patients with and without overweight/obesity. The effect of the link between overweight/obesity and T2DM on leptin and visfatin levels was examined using a generalized linear regression model. Results: There were 66 patients with T2DM, with a mean age of (49.70±9.45) years and a mean diabetes duration of (4.99±4.46) years, and there were 64 patients without T2DM, with a mean age of (43.89±0.20) years. The leptin [ (3.17±0.36) vs. (3.03±0.30) ng/mL; t=2.387, P=0.018] and visfatin levels [ (29.14±3.16) vs. (21.81±3.32) ng/mL; t=12.900, P<0.001] were significantly greater in T2DM patients than in patients without T2DM. The leptin level was significantly greater in patients with overweight/obesity than in those without overweight/obesity [ (3.27±0.32) vs. (2.92±0.26) ng/mL; t=6.634, P<0.001], and the visfatin level was significantly lower in patients with overweight/obesity than in those without overweight/obesity [(24.38±5.14) vs. (26.71±4.36) ng/mL; t=2.780, P=0.006]. Generalized linear regression analysis showed interacting effects of overweight/obesity and T2DM on leptin (β=0.286, P=0.003) and visfatin levels (β=2.709, P=0.008). Conclusion The interaction between overweight/obesity and T2DM affects leptin and visfatin levels.

Objective To investigate the effect of endoscopic prebiopsy forceps on the detection rate of polyps in the right semicolon.Method Clinical data of 148 patients diagnosed and treated from March 2022 to December 2022 who were detected as polyps in the right semicolon by general electronic colonoscopy were collected,and clinical data of the patients who underwent endoscopic prebiopsy forceps were re-examined and the patients underwent endoscopic treatment within 1 month.The differences in general data,polyp number detected,polyp size,morphology and pathological diagnosis between the two groups were analyzed and compared.Results 168 polyps were detected in the right semicolon in the general colonoscopy group,and 41 polyps were missed in reexamination using endoscopic prebiopsy forceps,with a missed diagnosis rate of 19.62%.The detection rate of<5 mm polyps was higher in the endoscopic prebiopsy forceps group than that of general colonoscopy group,the difference was statistically significant(P<0.05).The polyps in the two groups were mainly wide-basal type,and the pathological properties were mainly tubular adenoma,there was no statistical significance among all groups(P>0.05).No complications such as bleeding and perforation occurred in the two groups.Conclusion Endoscopic prebiopsy forceps can significantly improve the detection rate of polyps in the right semicolon,in particular,the intraoperative search for disappeared preoperatively identified intestinal polyps,as well as smaller diameter intestinal polyps,which is worthy of further clinical promotion.

Objective To investigate influence of continued-nursing on physical and mental health for elderly patients with spinal cord injury.Methods A total of 80 elderly spinal cord injury patients (ASIA grade A) were selected in our department and divided into observation and control groups based on random number table method.The control group received conventional nursing and discharge guidance, while observation group received continued-nursing for 6 months after discharge, including telephone follow-up, family visit, and theme education activities.Self-care ability and psychological states before and after intervention were evaluated.Results The scores of Functional Independence Measurement (FIM), HAMA, and HAMD showed no significant difference in both groups before intervention(P>0.05).However, the scores above in observation group had significant difference after 6 months of continued-nursing than that of control group (P<0.01).The incidence of complication in observation group was lower.Conclusion Continued-nursing can improve the rehabilitation adherence and self-management ability of elderly spinal cord injury patients after discharge, and reduce the incidence of complications.

Objective To investigate influence of continued-nursing on physical and mental health for elderly patients with spinal cord injury.Methods A total of 80 elderly spinal cord injury patients (ASIA grade A) were selected in our department and divided into observation and control groups based on random number table method.The control group received conventional nursing and discharge guidance, while observation group received continued-nursing for 6 months after discharge, including telephone follow-up, family visit, and theme education activities.Self-care ability and psychological states before and after intervention were evaluated.Results The scores of Functional Independence Measurement (FIM), HAMA, and HAMD showed no significant difference in both groups before intervention(P>0.05).However, the scores above in observation group had significant difference after 6 months of continued-nursing than that of control group (P<0.01).The incidence of complication in observation group was lower.Conclusion Continued-nursing can improve the rehabilitation adherence and self-management ability of elderly spinal cord injury patients after discharge, and reduce the incidence of complications.