1.Correlation between metabolic syndrome component aggregation and nonalcoholic fatty liver disease in a certain district of Urumqi’s check-up population
Hailili GULISIYA ; Hua YAO ; Shu-xia WANG ; Yu-shan WANG ; Tao LIU ; Zhen CHEN ; Tao, LUO
Chinese Journal of Disease Control & Prevention 2019;23(11):1358-1363
Objective The relationship between metabolic syndrome(MetS), metabolic syndrome score (MSS) and non-alcoholic fatty liver disease(NAFLD) in Urumqi was investigated by the MSS, reflecting the aggregation of MetS components. Methods The subjects were divided into non-NAFLD and NAFLD group by abdominal B ultrasound. The results of physical examination and blood biochemical examination were analyzed. The MSS was calculated and the relationship between the different aggregation of MSS and NAFLD was analyzed by Log-binomial regression. Results A total of 20 569 subjects were included in the study. The detection rate of MetS was 16.7%, the detection rate of NAFLD was 32.4%. Compared with non-NAFLD group, the systolic blood pressure, diastolic blood pressure,body mass index (BMI), waist circumference, fasting plasma glucose, triglyceride, total cholesterol, and low-density lipoprotein cholesterol were all increased in the NAFLD group, and the difference was statistically significant (P<0.05). After adjusting for gender, age, ethnicity and education level, Log-binomial regression analysis showed high BMI, hypertension and hyperglycemia. High triglycerides and low-density lipoproteins are the main risk factors for NAFLD (PR values were 3.194, 1.331, 1.623, 1.981, 1.254, respectively); the risk of NAFLD increased corresondingly when MSS, MSS0, MSS1, MSS2, MSS3, and MSS4 increased. The PR were 3.127, 4.983, 6.437, and 7.331, respectively. Conclusions The formation of NAFLD is not a single accumulation of liver fat, combined with abnormalities such as blood lipids, blood pressure, and blood sugar. The detection rate of male MetS and NAFLD was higher than that of female, but women with two abnormal metabolic indicators were more likely to develop into NAFLD. BMI as the obesity index has the strongest relationship with NAFLD, and NAFLD prevention should focus on obese people.
2. The confidence affects willingness to use pre-exposure prophylaxis among MSM, based on Path analysis
Tao LUO ; Hailili GULISIYA ; Zhen CHEN ; Xiaoqing TUO ; Aijie CAI ; Zhao ZHANG ; Jianghong DAI
Chinese Journal of Epidemiology 2019;40(10):1279-1284
Objective:
To analyze the influence of the confidence to pre-exposure prophylaxis (PrEP) on the willingness to use PrEP in men who have sex with men (MSM) by using the path analysis model based on structural equation model approach.
Methods:
A total of 550 MSM were recruited in Urumqi by snowball method and a questionnaire survey was conducted among them. According to the professional knowledge and analysis results of the confidence and willingness to use PrEP, structural equation model (SEM) analysis method was used to construct a path analysis model.
Results:
A total of 513 MSM participated in the survey. The modified path equation model was well fitted, with the modified fitting index as:
3.Evaluation of continuous metabolic syndrome score as a screening tool for metabolic syndrome in Xinjiang urban population aged 15-18 years
GULISIYA Hailili, WANG Shuxia, WANG Yushan, SU Yinxia, CHEN Zhen, LUO Tao, YAO Hua, DAI Jianghong
Chinese Journal of School Health 2020;41(1):100-102
Objective:
The purpose of the present study was to evaluate of continuous metabolic syndrome score (cMetS) in screening metabolic syndrome (MetS) and to determine the cut-off values in a representative sample of Xinjiang population aged 15 to 18 years old.
Methods:
A stratified cluster sampling was used to select participants aged 15-18 years from 13 cities in Xinjiang. cMetS was calculated by summing up the Zscores of standardized waist circumference, mean arterial pressure, high-density lipoprotein, triglyceride, and fasting blood glucose by age and gender.
Results:
Totally 16.3% of subjects were overweight, and 5.2% were obese. The proportion of overweight and obesity in males was significantly higher than that in females (18.1% vs 13.8%)(6.0% vs. 4.1%)(χ2=15.36,7.89,P<0.05). The prevalence of total MetS was 6.1%, with 6.6% and 5.4% for men and women, respectively. There was a correlation between cMetS and MetS components, and the average cMetS value increased with increasing MetS component(P<0.05). The total cut-off value of cMetS was 0.99 (sensitivity 68.0%, specificity 80.7%), and the area under the ROC curve was 84.9%. The cMetS scores for boys and girls were 0.80 and 1.48, respectively.
Conclusion
Compared with MetS, cMetS shows more accuracy in screening MetS among youth aged 15-18 years in both gender.
4. Rush poppers use and risks of human papillomavirus infection among men who have sex with men in Urumqi: mediation effect through high-risk sexual behaviors
Xiaoqing TUO ; Hui WANG ; Mahan YELEDAN ; Zhanlin ZHANG ; Zheng GONG ; Tian TIAN ; Zhen CHEN ; Hailili GULISIYA ; Jianghong DAI
Chinese Journal of Preventive Medicine 2019;53(2):202-205
Objective:
To study the prevalence of rush poppers use among men who have sex with men (MSM) in Urumqi and to analyze the mediating effect of high-risk sexual behavior between the use of rush poppers and human papillomavirus (HPV) infection.
Methods:
From January to June 2018, 651 MSM were recruited through network and publicity. Data was collected by using online questionnaire and anal swab were collected from them for HPV genotyping. According to Baron and Kenny