1.Application Effect of Weekly Maintenance Together for Detection Equipment by Persons Specifically Designated
Jiubo FAN ; Li SUN ; Haiju LIU
Journal of Modern Laboratory Medicine 2016;(1):161-164
Objective To explore the application effect of weekly maintenance together for detection equipment by persons specifically designated.Methods Firstly carries on the preliminary training and the organization of the examination for all junior technicians and nurses,the appropriate persons were selected.Secondly,the recruited personnel were trained and as-sessed by the manufacturer or equipment engineers.After obtaining a certificate of conformity,weekly centralized mainte-nance for detection equipment officially began to implement in August 2014.Maintenance time was designated as every Wednesday afternoon or evening.Two months after the operation the test carried out by the head of clinical laboratory and the equipment department engineers in strict accordance with the week maintenance prcedures for each instrument and each item,and on-site questions.Other personnel also participated in the test as a control group.After half a year,the question-naire was sent to all the inspectors,and the satisfaction rate about the maintenance of the instrument was counted.Results Seven personnel selected to participate in the weekly maintenance,includings two senior technicians,three technicians and two nurses.Experimental personnel BC5390,UF-1000i,BH5100Plus and BH2100,C8000 and i2000,ADVIA2400 average score was significantly higher than the control group.Before and after the programme,the average number of failures of the instrument was reduced from 22 to 8 times and the average satisfaction rate of the inspection personnel was 83.0%±5.0%and 98.0%±2.0% respectively,and the difference was statistically significant.Conclusion Weekly centralized maintenance for detection equipment by persons specifically designated can truly implement instrument maintenance requirements,and at the same time with the implementation of the program,the failure times is greatly reduced,which is beneficial to improve the quality of inspection and to avoid the medical risks caused by TAT.
2.Ethical Thinking on Hospital Laboratory Information System
Dan SHEN ; Li SUN ; Haiju LIU ; Jiubo FAN ; Zhishan LI
Chinese Medical Ethics 2015;(4):611-614
This paper discussed the existing problems of Information System ( LIS) from six aspects, inclu-ding:the security and the expansion of the function, protection of patients′privacy, the establishment of emergency response mechanisms, authenticity and accuracy of data and the risks for auto-approval rules, etc.The authors also analysed the necessity of its rectification from the perspective of ethics, proposed improvement programme and suggestions: strengthening the safety management systems and data, ensuring special check the confidentiality of the project, protect the patient′s privacy;setting up emergency mechanism;hospital based on the actual workload and resources to determine the LIS function module; regularly checking the test data, to avoid occupational inju-ries;continuously improving the rigour of automatic approval rules.
3.Effect of inhibition of PAR2?PKA/PKCε signaling pathway in periphery neurons on the transition from acute to chronic pain
Junfan FANG ; Sisi WANG ; Haiju SUN ; Xiaomei SHAO ; Yi LIANG ; Jianqiao FANG ; Junying DU
Acta Laboratorium Animalis Scientia Sinica 2018;26(1):13-19
Objective To detect the role of PAR2-PKA/PKCε signaling pathway in periphery neurons in the tran-sition from acute to chronic pain,and investigate the possible approach to prevent both acute and chronic pain simultane-ously. Methods SD rats were randomly divided into control group,sham model group,model group,iPAR2-1 group and iPAR2-2 group. The hyperalgesia priming model was established by injection of carrageenan and PGE2 into the left hind-paw except control and sham model group. PGE2 was administrated at 7 days after carrageenan injection. The PAR2 inhibi-tor was administrated before and after PGE2 injection separately in the iPAR2-1 group and iPAR2-2 group. The paw with-drawal thresholds(PWTs)of rats in each group was detected before and at 5 h,3 d,6 d,7 d 0.5 h,7 d 4 h,7 d 24 h after carrageenan injection. The expression level of PAR2, PKA and PKCε proteins in the dorsal root ganglion(DRG) were detected at 24 h after carrageenan injection. Results The hyperalgesia priming model was successfully generated. When PGE2 was administrated at 7 days after carrageenan injection, the hyperalgesia induced by PGE2 was significantly prolonged. The PWTs of rats in the model group were significantly lower than that of the control and sham model groups(P<0.01),though the PWTs of sham model group had no significant difference with the control on 7 d 24 h after carrageenan injection(P>0.05). The expression level of PAR2 and PKCε in the ipsilateral DRG neurons were significantly increased on 7 d 24 h after carrageenan injection,when compared with the control and sham model groups(P<0.05). PAR2 inhibi-tor prevented the prolonged hyperalgesia induced by PGE2(P<0.05)and decreased the PKCε expression in DRG neurons whenever it was given(P<0.05). However,PAR2 inhibitor did not regulate the acute inflammatory pain of PGE2 and the expression of PKA in DRG neurons(P>0.05). Conclusions Inhibition of the expression of PAR2 can prevent the tran-sition from acute to chronic pain. This effect may be related with the inhibitory effect on the activation of PAR2-PKCε sig-naling pathway in DRG neurons. However,inhibition of PAR2 can not regulate the acute pain. These may because of that the PAR2-PKA signaling pathway does not play a role in acute pain.
4.Professor ' clinical experience in the treatment of primary cervical dystonia.
Xiaoyur LI ; Haiju SUN ; Jianqiao FANG
Chinese Acupuncture & Moxibustion 2018;38(9):985-988
Professor ' clinical experience in the treatment of primary cervical dystonia based on the syndrome differentiation of TCM was explored preliminarily. Based on the disease identification of western medicine and the syndrome differentiation of TCM, in combination with the differentiations of meridians and collaterals of acupuncture, Professor proposes the three-dimensional system of diagnosis and treatment of acupuncture, named "disease differentiation, TCM syndrome differentiation and meridian differentiation". Regarding the diagnosis and treatment of primary cervical dystonia, the physical examination of nerve system, TCM syndrome differentiation and meridian differentiation are equally important. It is pointed out that the key pathogenesis of the disease is and blood obstruction and the malnutrition in the muscle regions of meridians. Hence, the treating principle is proposed as eliminating the exogenous pathogens, regulating and blood and unblocking the muscle regions of meridians. Professor also stresses that the affected sites and the factors of dystonia should be considered in acupuncture treatment. The local points are mainly those adjacent to the responsible muscles with the motor disturbance in the neck region. "Xinshe" point (Extra) is taken as the empirical point. The distal points are selected in accordance with the three-dimensional system of diagnosis and treatment. At the same time, the percutaneous acupoint electric stimulation is applied to the starting and ending points or the conjunctive points of the affected muscles, acting on regulating , nourishing blood and promoting the circulation in meridians and collaterals.
Acupuncture Therapy
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Torticollis