ObjectiveTo investigate the clinical manifestations, rehabilitation evaluation and treatment for Thallium poisoning. MethodsA patient with Thallium poisoning was reviewed. ResultsGastroenteritis, peripheral polyneuropathy and alopecia were the typical symptoms of Thallium poisoning. After the shortwave therapy, medium frequency electrotherapy and physical therapy, the index of sensory, extremities perimeter and muscle strength, sitting-stand-walking, ADL, and emotions were apparently improved. ConclusionComprehensive rehabilitation with shortwave therapy, medium frequency electrotherapy and physical therapy might be effective treatments for the patients with Thallium poisoning.