Objective:To investigate the present situation of anticipatory grief of main caregivers of elderly patients with acetabular fractures and to explore its influencing factors.Methods:Using the convenient sampling method, a total of 168 main caregivers of elderly patients with acetabular fractures who underwent surgical treatment in the First People's Hospital of Fuyang District in Hangzhou and were discharged from the hospital from January 2018 to December 2019 were selected as research objects. General information questionnaire, Family Disease Burden Scale and Anticipatory Grief Scale were used to investigate.Results:The score of Anticipatory Grief Scale of primary caregivers for elderly patients with acetabular fractures was (69.61±6.35) . The results of multiple regression analysis showed that the age of the main caregivers of elderly patients with acetabular fractures, the relationship with the patients, the time of care and the degree of family disease burden were the main influencing factors of anticipatory grief ( P<0.05) . Conclusions:The main caregivers of elderly patients with acetabular fractures have a moderate level of anticipatory grief. While paying attention to the psychological problems of patients, medical staff should also include caregivers in the object category of psychological care and actively explore effective nursing measures to promote the physical and mental health of caregivers.